Metadata-Version: 2.1
Name: GFHunter
Version: 1.0.0
Summary: GFHunter is a long read sequence transcriptome alignment-based fusion genes detection tool.
Home-page: https://github.com/luzhenhao-HIT/GFHunter
Author: Zhenhao Lu
Author-email: luzhenhao.hit@gmail.com
Maintainer: Zhenhao Lu
Maintainer-email: luzhenhao.hit@gmail.com
License: MIT License
Classifier: Operating System :: OS Independent
Classifier: License :: OSI Approved :: MIT License
Classifier: Programming Language :: Python :: 3
Requires-Python: >=3
Requires-Dist: numpy
Requires-Dist: scipy
Requires-Dist: intervaltree
Requires-Dist: pyabpoa

- **GFHunter** is a long read sequence transcriptome alignment-based fusion genes detection tool.
- **Indexing**: User can download the prepared index folder based on **GENCODE release 44** here or create a new index by GFHunter **index** function.
- **Detection**: GFHunter detects fusions in **long read RNA-seq data**, user just need **index folder** and **long read data** under detection.
- Benchmark evaluations position GFHunter as redefining the analytical frontiers of gene fusion detection:
  1. **Lowest false-positive fusion rates** in non-tumor data.
  2. Achieves a **substantially higher F1-score** in real cancer cell lines evaluation.
  3. Operates **many times faster** and requires **fewer and stable memory** than other tools.
