{
  "name": "Biolink-Model",
  "description": "Entity and association taxonomy and datamodel for life-sciences data",
  "id": "https://w3id.org/biolink/biolink-model",
  "version": "1.8.2",
  "imports": [
    "linkml:types"
  ],
  "license": "https://creativecommons.org/publicdomain/zero/1.0/",
  "prefixes": [
    {
      "prefix_prefix": "Aeolus",
      "prefix_reference": "http://translator.ncats.nih.gov/Aeolus_"
    },
    {
      "prefix_prefix": "alliancegenome",
      "prefix_reference": "https://www.alliancegenome.org/"
    },
    {
      "prefix_prefix": "biolink",
      "prefix_reference": "https://w3id.org/biolink/vocab/"
    },
    {
      "prefix_prefix": "linkml",
      "prefix_reference": "https://w3id.org/linkml/"
    },
    {
      "prefix_prefix": "CAID",
      "prefix_reference": "http://reg.clinicalgenome.org/redmine/projects/registry/genboree_registry/by_caid?caid="
    },
    {
      "prefix_prefix": "CHADO",
      "prefix_reference": "http://gmod.org/wiki/Chado/"
    },
    {
      "prefix_prefix": "ChemBank",
      "prefix_reference": "http://chembank.broadinstitute.org/chemistry/viewMolecule.htm?cbid="
    },
    {
      "prefix_prefix": "chembio",
      "prefix_reference": "http://translator.ncats.nih.gov/chembio_"
    },
    {
      "prefix_prefix": "CHEMBL.MECHANISM",
      "prefix_reference": "https://www.ebi.ac.uk/chembl/mechanism/inspect/"
    },
    {
      "prefix_prefix": "CID",
      "prefix_reference": "http://pubchem.ncbi.nlm.nih.gov/compound/"
    },
    {
      "prefix_prefix": "COAR_RESOURCE",
      "prefix_reference": "http://purl.org/coar/resource_type/"
    },
    {
      "prefix_prefix": "CPT",
      "prefix_reference": "https://www.ama-assn.org/practice-management/cpt/"
    },
    {
      "prefix_prefix": "CTD",
      "prefix_reference": "http://translator.ncats.nih.gov/CTD_"
    },
    {
      "prefix_prefix": "DGIdb",
      "prefix_reference": "https://www.dgidb.org/interaction_types"
    },
    {
      "prefix_prefix": "dcat",
      "prefix_reference": "http://www.w3.org/ns/dcat#"
    },
    {
      "prefix_prefix": "dct",
      "prefix_reference": "http://purl.org/dc/terms/"
    },
    {
      "prefix_prefix": "doi",
      "prefix_reference": "https://doi.org/"
    },
    {
      "prefix_prefix": "DrugCentral",
      "prefix_reference": "http://translator.ncats.nih.gov/DrugCentral_"
    },
    {
      "prefix_prefix": "ECTO",
      "prefix_reference": "http://purl.obolibrary.org/obo/ECTO_"
    },
    {
      "prefix_prefix": "EDAM-DATA",
      "prefix_reference": "http://edamontology.org/data_"
    },
    {
      "prefix_prefix": "EDAM-FORMAT",
      "prefix_reference": "http://edamontology.org/format_"
    },
    {
      "prefix_prefix": "EDAM-OPERATION",
      "prefix_reference": "http://edamontology.org/operation_"
    },
    {
      "prefix_prefix": "EDAM-TOPIC",
      "prefix_reference": "http://edamontology.org/topic_"
    },
    {
      "prefix_prefix": "EFO",
      "prefix_reference": "http://www.ebi.ac.uk/efo/EFO_"
    },
    {
      "prefix_prefix": "ExO",
      "prefix_reference": "http://purl.obolibrary.org/obo/ExO_"
    },
    {
      "prefix_prefix": "fabio",
      "prefix_reference": "http://purl.org/spar/fabio/"
    },
    {
      "prefix_prefix": "foaf",
      "prefix_reference": "http://xmlns.com/foaf/0.1/"
    },
    {
      "prefix_prefix": "foodb.compound",
      "prefix_reference": "http://foodb.ca/compounds/"
    },
    {
      "prefix_prefix": "GAMMA",
      "prefix_reference": "http://translator.renci.org/GAMMA_"
    },
    {
      "prefix_prefix": "gff3",
      "prefix_reference": "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#"
    },
    {
      "prefix_prefix": "GOREL",
      "prefix_reference": "http://purl.obolibrary.org/obo/GOREL_"
    },
    {
      "prefix_prefix": "GOP",
      "prefix_reference": "http://purl.obolibrary.org/obo/go#"
    },
    {
      "prefix_prefix": "gpi",
      "prefix_reference": "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#"
    },
    {
      "prefix_prefix": "GSID",
      "prefix_reference": "https://scholar.google.com/citations?user="
    },
    {
      "prefix_prefix": "GTEx",
      "prefix_reference": "https://www.gtexportal.org/home/gene/"
    },
    {
      "prefix_prefix": "GTOPDB",
      "prefix_reference": "https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId="
    },
    {
      "prefix_prefix": "gtpo",
      "prefix_reference": "https://rdf.guidetopharmacology.org/ns/gtpo#"
    },
    {
      "prefix_prefix": "HANCESTRO",
      "prefix_reference": "http://www.ebi.ac.uk/ancestro/ancestro_"
    },
    {
      "prefix_prefix": "HCPCS",
      "prefix_reference": "http://purl.bioontology.org/ontology/HCPCS/"
    },
    {
      "prefix_prefix": "hetio",
      "prefix_reference": "http://translator.ncats.nih.gov/hetio_"
    },
    {
      "prefix_prefix": "HsapDv",
      "prefix_reference": "http://purl.obolibrary.org/obo/HsapDv_"
    },
    {
      "prefix_prefix": "ICD0",
      "prefix_reference": "http://translator.ncats.nih.gov/ICD0_"
    },
    {
      "prefix_prefix": "ICD10",
      "prefix_reference": "http://translator.ncats.nih.gov/ICD10_"
    },
    {
      "prefix_prefix": "ICD9",
      "prefix_reference": "http://translator.ncats.nih.gov/ICD9_"
    },
    {
      "prefix_prefix": "interpro",
      "prefix_reference": "https://www.ebi.ac.uk/interpro/entry/"
    },
    {
      "prefix_prefix": "INO",
      "prefix_reference": "http://purl.obolibrary.org/obo/INO_"
    },
    {
      "prefix_prefix": "isbn",
      "prefix_reference": "https://www.isbn-international.org/identifier/"
    },
    {
      "prefix_prefix": "isni",
      "prefix_reference": "https://isni.org/isni/"
    },
    {
      "prefix_prefix": "issn",
      "prefix_reference": "https://portal.issn.org/resource/ISSN/"
    },
    {
      "prefix_prefix": "KEGG.BRITE",
      "prefix_reference": "http://www.kegg.jp/entry/"
    },
    {
      "prefix_prefix": "KEGG.DGROUP",
      "prefix_reference": "http://www.kegg.jp/entry/"
    },
    {
      "prefix_prefix": "KEGG.ENZYME",
      "prefix_reference": "http://www.kegg.jp/entry/"
    },
    {
      "prefix_prefix": "KEGG.GENE",
      "prefix_reference": "http://www.kegg.jp/entry/"
    },
    {
      "prefix_prefix": "KEGG.RCLASS",
      "prefix_reference": "http://www.kegg.jp/entry/"
    },
    {
      "prefix_prefix": "LOINC",
      "prefix_reference": "http://loinc.org/rdf/"
    },
    {
      "prefix_prefix": "medgen",
      "prefix_reference": "https://www.ncbi.nlm.nih.gov/medgen/"
    },
    {
      "prefix_prefix": "MetaCyc",
      "prefix_reference": "http://translator.ncats.nih.gov/MetaCyc_"
    },
    {
      "prefix_prefix": "MI",
      "prefix_reference": "http://purl.obolibrary.org/obo/MI_"
    },
    {
      "prefix_prefix": "MSigDB",
      "prefix_reference": "https://www.gsea-msigdb.org/gsea/msigdb/"
    },
    {
      "prefix_prefix": "NDDF",
      "prefix_reference": "http://purl.bioontology.org/ontology/NDDF/"
    },
    {
      "prefix_prefix": "NLMID",
      "prefix_reference": "https://www.ncbi.nlm.nih.gov/nlmcatalog/?term="
    },
    {
      "prefix_prefix": "OBAN",
      "prefix_reference": "http://purl.org/oban/"
    },
    {
      "prefix_prefix": "oboformat",
      "prefix_reference": "http://www.geneontology.org/formats/oboInOWL#"
    },
    {
      "prefix_prefix": "OBOREL",
      "prefix_reference": "http://purl.obolibrary.org/obo/RO_"
    },
    {
      "prefix_prefix": "ORCID",
      "prefix_reference": "https://orcid.org/"
    },
    {
      "prefix_prefix": "ORPHA",
      "prefix_reference": "http://www.orpha.net/ORDO/Orphanet_"
    },
    {
      "prefix_prefix": "os",
      "prefix_reference": "https://github.com/cmungall/owlstar/blob/master/owlstar.ttl"
    },
    {
      "prefix_prefix": "PathWhiz",
      "prefix_reference": "http://smpdb.ca/pathways/#"
    },
    {
      "prefix_prefix": "PATO-PROPERTY",
      "prefix_reference": "http://purl.obolibrary.org/obo/pato#"
    },
    {
      "prefix_prefix": "pav",
      "prefix_reference": "http://purl.org/pav/"
    },
    {
      "prefix_prefix": "PDQ",
      "prefix_reference": "https://www.cancer.gov/publications/pdq#"
    },
    {
      "prefix_prefix": "PHAROS",
      "prefix_reference": "http://pharos.nih.gov"
    },
    {
      "prefix_prefix": "prov",
      "prefix_reference": "http://www.w3.org/ns/prov#"
    },
    {
      "prefix_prefix": "qud",
      "prefix_reference": "http://qudt.org/1.1/schema/qudt#"
    },
    {
      "prefix_prefix": "REPODB",
      "prefix_reference": "http://apps.chiragjpgroup.org/repoDB/"
    },
    {
      "prefix_prefix": "ResearchID",
      "prefix_reference": "https://publons.com/researcher/"
    },
    {
      "prefix_prefix": "RO",
      "prefix_reference": "http://purl.obolibrary.org/obo/RO_"
    },
    {
      "prefix_prefix": "RTXKG1",
      "prefix_reference": "http://kg1endpoint.rtx.ai/"
    },
    {
      "prefix_prefix": "RXNORM",
      "prefix_reference": "http://purl.bioontology.org/ontology/RXNORM/"
    },
    {
      "prefix_prefix": "RXCUI",
      "prefix_reference": "https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm="
    },
    {
      "prefix_prefix": "schema",
      "prefix_reference": "http://schema.org/"
    },
    {
      "prefix_prefix": "ScopusID",
      "prefix_reference": "https://www.scopus.com/authid/detail.uri?authorId="
    },
    {
      "prefix_prefix": "SEMMEDDB",
      "prefix_reference": "https://skr3.nlm.nih.gov/SemMedDB"
    },
    {
      "prefix_prefix": "SIO",
      "prefix_reference": "http://semanticscience.org/resource/SIO_"
    },
    {
      "prefix_prefix": "SNPEFF",
      "prefix_reference": "http://translator.ncats.nih.gov/SNPEFF_"
    },
    {
      "prefix_prefix": "UBERGRAPH",
      "prefix_reference": "http://translator.renci.org/ubergraph-axioms.ofn#"
    },
    {
      "prefix_prefix": "UBERON_CORE",
      "prefix_reference": "http://purl.obolibrary.org/obo/uberon/core#"
    },
    {
      "prefix_prefix": "UMLSSC",
      "prefix_reference": "https://metamap.nlm.nih.gov/Docs/SemanticTypes_2018AB.txt/code#"
    },
    {
      "prefix_prefix": "UMLSSG",
      "prefix_reference": "https://metamap.nlm.nih.gov/Docs/SemGroups_2018.txt/group#"
    },
    {
      "prefix_prefix": "UMLSST",
      "prefix_reference": "https://metamap.nlm.nih.gov/Docs/SemanticTypes_2018AB.txt/type#"
    },
    {
      "prefix_prefix": "VANDF",
      "prefix_reference": "https://www.nlm.nih.gov/research/umls/sourcereleasedocs/current/VANDF/"
    },
    {
      "prefix_prefix": "VMC",
      "prefix_reference": "https://github.com/ga4gh/vr-spec/"
    },
    {
      "prefix_prefix": "WBVocab",
      "prefix_reference": "http://bio2rdf.org/wormbase_vocabulary"
    },
    {
      "prefix_prefix": "WIKIDATA",
      "prefix_reference": "https://www.wikidata.org/wiki/"
    },
    {
      "prefix_prefix": "WIKIDATA_PROPERTY",
      "prefix_reference": "https://www.wikidata.org/wiki/Property:"
    },
    {
      "prefix_prefix": "wgs",
      "prefix_reference": "http://www.w3.org/2003/01/geo/wgs84_pos"
    }
  ],
  "emit_prefixes": [
    "rdf",
    "rdfs",
    "xsd",
    "skos",
    "OIO",
    "BIOGRID"
  ],
  "default_curi_maps": [
    "obo_context",
    "idot_context",
    "monarch_context",
    "semweb_context"
  ],
  "default_prefix": "biolink",
  "default_range": "string",
  "subsets": [
    {
      "name": "model_organism_database",
      "definition_uri": "https://w3id.org/biolink/vocab/ModelOrganismDatabase",
      "description": "Subset that is relevant for a typical Model Organism Database (MOD)",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "@type": "SubsetDefinition"
    },
    {
      "name": "translator_minimal",
      "definition_uri": "https://w3id.org/biolink/vocab/TranslatorMinimal",
      "description": "Minimum subset of translator work",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "@type": "SubsetDefinition"
    },
    {
      "name": "samples",
      "definition_uri": "https://w3id.org/biolink/vocab/Samples",
      "description": "Sample/biosample datamodel",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "@type": "SubsetDefinition"
    },
    {
      "name": "testing",
      "definition_uri": "https://w3id.org/biolink/vocab/Testing",
      "description": "TBD",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "@type": "SubsetDefinition"
    }
  ],
  "types": [
    {
      "name": "chemical_formula_value",
      "definition_uri": "https://w3id.org/biolink/vocab/ChemicalFormulaValue",
      "description": "A chemical formula",
      "notes": [
        "Should be implemented as a stronger type"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "base": "str",
      "uri": "http://www.w3.org/2001/XMLSchema#string",
      "@type": "TypeDefinition"
    },
    {
      "name": "category_type",
      "definition_uri": "https://w3id.org/biolink/vocab/CategoryType",
      "description": "A primitive type in which the value denotes a class within the biolink model. The value must be a URI or a CURIE. In a Neo4j representation, the value should be the CURIE for the biolink class, for example biolink:Gene. For an RDF representation, the value should be a URI such as https://w3id.org/biolink/vocab/Gene",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "uriorcurie",
      "base": "URIorCURIE",
      "uri": "http://www.w3.org/2001/XMLSchema#anyURI",
      "repr": "str",
      "@type": "TypeDefinition"
    },
    {
      "name": "iri_type",
      "definition_uri": "https://w3id.org/biolink/vocab/IriType",
      "description": "An IRI",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "uriorcurie",
      "base": "URIorCURIE",
      "uri": "http://www.w3.org/2001/XMLSchema#anyURI",
      "repr": "str",
      "@type": "TypeDefinition"
    },
    {
      "name": "label_type",
      "definition_uri": "https://w3id.org/biolink/vocab/LabelType",
      "description": "A string that provides a human-readable name for an entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "string",
      "base": "str",
      "uri": "http://www.w3.org/2001/XMLSchema#string",
      "@type": "TypeDefinition"
    },
    {
      "name": "predicate_type",
      "definition_uri": "https://w3id.org/biolink/vocab/PredicateType",
      "description": "A CURIE from the biolink related_to hierarchy. For example, biolink:related_to, biolink:causes, biolink:treats.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "uriorcurie",
      "base": "URIorCURIE",
      "uri": "http://www.w3.org/2001/XMLSchema#anyURI",
      "repr": "str",
      "@type": "TypeDefinition"
    },
    {
      "name": "narrative_text",
      "definition_uri": "https://w3id.org/biolink/vocab/NarrativeText",
      "description": "A string that provides a human-readable description of something",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "string",
      "base": "str",
      "uri": "http://www.w3.org/2001/XMLSchema#string",
      "@type": "TypeDefinition"
    },
    {
      "name": "symbol_type",
      "definition_uri": "https://w3id.org/biolink/vocab/SymbolType",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "string",
      "base": "str",
      "uri": "http://www.w3.org/2001/XMLSchema#string",
      "@type": "TypeDefinition"
    },
    {
      "name": "frequency_value",
      "definition_uri": "https://w3id.org/biolink/vocab/FrequencyValue",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "string",
      "base": "str",
      "uri": "http://purl.obolibrary.org/obo/UO_0000105",
      "@type": "TypeDefinition"
    },
    {
      "name": "percentage_frequency_value",
      "definition_uri": "https://w3id.org/biolink/vocab/PercentageFrequencyValue",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "double",
      "base": "float",
      "uri": "http://purl.obolibrary.org/obo/UO_0000187",
      "@type": "TypeDefinition"
    },
    {
      "name": "quotient",
      "definition_uri": "https://w3id.org/biolink/vocab/Quotient",
      "aliases": [
        "ratio"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "double",
      "base": "float",
      "uri": "http://purl.obolibrary.org/obo/UO_0010006",
      "@type": "TypeDefinition"
    },
    {
      "name": "unit",
      "id_prefixes": [
        "UO"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Unit",
      "exact_mappings": [
        "qud:Unit"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "string",
      "base": "str",
      "uri": "http://purl.obolibrary.org/obo/UO_0000000",
      "@type": "TypeDefinition"
    },
    {
      "name": "time_type",
      "definition_uri": "https://w3id.org/biolink/vocab/TimeType",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "time",
      "base": "XSDTime",
      "uri": "http://www.w3.org/2001/XMLSchema#dateTime",
      "repr": "str",
      "@type": "TypeDefinition"
    },
    {
      "name": "biological_sequence",
      "definition_uri": "https://w3id.org/biolink/vocab/BiologicalSequence",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "typeof": "string",
      "base": "str",
      "uri": "http://www.w3.org/2001/XMLSchema#string",
      "@type": "TypeDefinition"
    },
    {
      "name": "string",
      "definition_uri": "https://w3id.org/linkml/String",
      "description": "A character string",
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "str",
      "uri": "http://www.w3.org/2001/XMLSchema#string",
      "@type": "TypeDefinition"
    },
    {
      "name": "integer",
      "definition_uri": "https://w3id.org/linkml/Integer",
      "description": "An integer",
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "int",
      "uri": "http://www.w3.org/2001/XMLSchema#integer",
      "@type": "TypeDefinition"
    },
    {
      "name": "boolean",
      "definition_uri": "https://w3id.org/linkml/Boolean",
      "description": "A binary (true or false) value",
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "Bool",
      "uri": "http://www.w3.org/2001/XMLSchema#boolean",
      "repr": "bool",
      "@type": "TypeDefinition"
    },
    {
      "name": "float",
      "definition_uri": "https://w3id.org/linkml/Float",
      "description": "A real number that conforms to the xsd:float specification",
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "float",
      "uri": "http://www.w3.org/2001/XMLSchema#float",
      "@type": "TypeDefinition"
    },
    {
      "name": "double",
      "definition_uri": "https://w3id.org/linkml/Double",
      "description": "A real number that conforms to the xsd:double specification",
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "float",
      "uri": "http://www.w3.org/2001/XMLSchema#double",
      "@type": "TypeDefinition"
    },
    {
      "name": "decimal",
      "definition_uri": "https://w3id.org/linkml/Decimal",
      "description": "A real number with arbitrary precision that conforms to the xsd:decimal specification",
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "Decimal",
      "uri": "http://www.w3.org/2001/XMLSchema#decimal",
      "@type": "TypeDefinition"
    },
    {
      "name": "time",
      "definition_uri": "https://w3id.org/linkml/Time",
      "description": "A time object represents a (local) time of day, independent of any particular day",
      "notes": [
        "URI is dateTime because OWL reasoners don't work with straight date or time"
      ],
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "XSDTime",
      "uri": "http://www.w3.org/2001/XMLSchema#dateTime",
      "repr": "str",
      "@type": "TypeDefinition"
    },
    {
      "name": "date",
      "definition_uri": "https://w3id.org/linkml/Date",
      "description": "a date (year, month and day) in an idealized calendar",
      "notes": [
        "URI is dateTime because OWL reasoners don't work with straight date or time"
      ],
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "XSDDate",
      "uri": "http://www.w3.org/2001/XMLSchema#date",
      "repr": "str",
      "@type": "TypeDefinition"
    },
    {
      "name": "datetime",
      "definition_uri": "https://w3id.org/linkml/Datetime",
      "description": "The combination of a date and time",
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "XSDDateTime",
      "uri": "http://www.w3.org/2001/XMLSchema#dateTime",
      "repr": "str",
      "@type": "TypeDefinition"
    },
    {
      "name": "uriorcurie",
      "definition_uri": "https://w3id.org/linkml/Uriorcurie",
      "description": "a URI or a CURIE",
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "URIorCURIE",
      "uri": "http://www.w3.org/2001/XMLSchema#anyURI",
      "repr": "str",
      "@type": "TypeDefinition"
    },
    {
      "name": "uri",
      "definition_uri": "https://w3id.org/linkml/Uri",
      "description": "a complete URI",
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "URI",
      "uri": "http://www.w3.org/2001/XMLSchema#anyURI",
      "repr": "str",
      "@type": "TypeDefinition"
    },
    {
      "name": "ncname",
      "definition_uri": "https://w3id.org/linkml/Ncname",
      "description": "Prefix part of CURIE",
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "NCName",
      "uri": "http://www.w3.org/2001/XMLSchema#string",
      "repr": "str",
      "@type": "TypeDefinition"
    },
    {
      "name": "objectidentifier",
      "definition_uri": "https://w3id.org/linkml/Objectidentifier",
      "description": "A URI or CURIE that represents an object in the model.",
      "comments": [
        "Used for inheritence and type checking"
      ],
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "ElementIdentifier",
      "uri": "http://www.w3.org/ns/shex#iri",
      "repr": "str",
      "@type": "TypeDefinition"
    },
    {
      "name": "nodeidentifier",
      "definition_uri": "https://w3id.org/linkml/Nodeidentifier",
      "description": "A URI, CURIE or BNODE that represents a node in a model.",
      "from_schema": "https://w3id.org/linkml/types",
      "imported_from": "linkml:types",
      "base": "NodeIdentifier",
      "uri": "http://www.w3.org/ns/shex#nonLiteral",
      "repr": "str",
      "@type": "TypeDefinition"
    }
  ],
  "enums": [
    {
      "name": "logical_interpretation_enum",
      "definition_uri": "https://w3id.org/biolink/vocab/LogicalInterpretationEnum",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "permissible_values": [
        {
          "text": "SomeSome",
          "description": "A modifier on a triple that causes the triple to be interpreted as a some-some statement",
          "meaning": "os:SomeSomeInterpretation"
        },
        {
          "text": "AllSome",
          "description": "A modifier on a triple that causes the triple to be interpreted as an all-some statement.",
          "meaning": "os:AllSomeInterpretation"
        },
        {
          "text": "InverseAllSome"
        }
      ]
    }
  ],
  "slots": [
    {
      "name": "has_attribute",
      "definition_uri": "https://w3id.org/biolink/vocab/has_attribute",
      "exact_mappings": [
        "http://semanticscience.org/resource/SIO_000008"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/OBI_0001927"
      ],
      "narrow_mappings": [
        "http://purl.org/oban/association_has_subject_property",
        "http://purl.org/oban/association_has_object_property",
        "https://www.ama-assn.org/practice-management/cpt/has_possibly_included_panel_element",
        "http://identifiers.org/drugbank/category",
        "http://www.ebi.ac.uk/efo/EFO_is_executed_in",
        "http://www.ebi.ac.uk/ancestro/ancestro_0301",
        "http://loinc.org/rdf/has_action_guidance",
        "http://loinc.org/rdf/has_adjustment",
        "http://loinc.org/rdf/has_aggregation_view",
        "http://loinc.org/rdf/has_approach_guidance",
        "http://loinc.org/rdf/has_divisor",
        "http://loinc.org/rdf/has_exam",
        "http://loinc.org/rdf/has_method",
        "http://loinc.org/rdf/has_modality_subtype",
        "http://loinc.org/rdf/has_object_guidance",
        "http://loinc.org/rdf/has_scale",
        "http://loinc.org/rdf/has_suffix",
        "http://loinc.org/rdf/has_time_aspect",
        "http://loinc.org/rdf/has_time_modifier",
        "http://loinc.org/rdf/has_timing_of",
        "http://purl.obolibrary.org/obo/NCIT_disease_is_grade",
        "http://purl.obolibrary.org/obo/NCIT_disease_is_stage",
        "http://purl.obolibrary.org/obo/NCIT_eo_disease_has_property_or_attribute",
        "http://purl.obolibrary.org/obo/NCIT_has_data_element",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_administration_method",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_basic_dose_form",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_intended_site",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_release_characteristics",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_state_of_matter",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_transformation",
        "http://purl.obolibrary.org/obo/NCIT_is_qualified_by",
        "http://purl.obolibrary.org/obo/NCIT_qualifier_applies_to",
        "http://purl.obolibrary.org/obo/NCIT_role_has_domain",
        "http://purl.obolibrary.org/obo/NCIT_role_has_range",
        "http://purl.obolibrary.org/obo/INO_0000154",
        "http://www.ebi.ac.uk/ancestro/ancestro_0308",
        "http://purl.obolibrary.org/obo/OMIM_has_inheritance_type",
        "http://www.orpha.net/ORDO/Orphanet_C016",
        "http://www.orpha.net/ORDO/Orphanet_C017",
        "http://purl.obolibrary.org/obo/RO_0000053",
        "http://purl.obolibrary.org/obo/RO_0000086",
        "http://purl.obolibrary.org/obo/RO_0000087",
        "http://purl.obolibrary.org/obo/SNOMED_has_access",
        "http://purl.obolibrary.org/obo/SNOMED_has_clinical_course",
        "http://purl.obolibrary.org/obo/SNOMED_has_count_of_base_of_active_ingredient",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_administration_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_release_characteristic",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_transformation",
        "http://purl.obolibrary.org/obo/SNOMED_has_finding_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_finding_informer",
        "http://purl.obolibrary.org/obo/SNOMED_has_inherent_attribute",
        "http://purl.obolibrary.org/obo/SNOMED_has_intent",
        "http://purl.obolibrary.org/obo/SNOMED_has_interpretation",
        "http://purl.obolibrary.org/obo/SNOMED_has_laterality",
        "http://purl.obolibrary.org/obo/SNOMED_has_measurement_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_priority",
        "http://purl.obolibrary.org/obo/SNOMED_has_procedure_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_process_duration",
        "http://purl.obolibrary.org/obo/SNOMED_has_property",
        "http://purl.obolibrary.org/obo/SNOMED_has_revision_status",
        "http://purl.obolibrary.org/obo/SNOMED_has_scale_type",
        "http://purl.obolibrary.org/obo/SNOMED_has_severity",
        "http://purl.obolibrary.org/obo/SNOMED_has_specimen",
        "http://purl.obolibrary.org/obo/SNOMED_has_state_of_matter",
        "http://purl.obolibrary.org/obo/SNOMED_has_subject_relationship_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_surgical_approach",
        "http://purl.obolibrary.org/obo/SNOMED_has_technique",
        "http://purl.obolibrary.org/obo/SNOMED_has_temporal_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_time_aspect",
        "http://purl.obolibrary.org/obo/SNOMED_has_units",
        "http://identifiers.org/umls/has_structural_class",
        "http://identifiers.org/umls/has_supported_concept_property",
        "http://identifiers.org/umls/has_supported_concept_relationship",
        "http://identifiers.org/umls/may_be_qualified_by"
      ],
      "description": "connects any entity to an attribute",
      "in_subset": [
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "domain": "Entity",
      "slot_uri": "https://w3id.org/biolink/vocab/has_attribute",
      "multivalued": true,
      "inlined": true,
      "owner": "Entity",
      "domain_of": [
        "Entity"
      ],
      "range": "Attribute",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_attribute_type",
      "definition_uri": "https://w3id.org/biolink/vocab/has_attribute_type",
      "narrow_mappings": [
        "http://loinc.org/rdf/has_modality_type",
        "http://loinc.org/rdf/has_view_type"
      ],
      "description": "connects an attribute to a class that describes it",
      "in_subset": [
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "domain": "Attribute",
      "slot_uri": "https://w3id.org/biolink/vocab/has_attribute_type",
      "inlined": true,
      "owner": "Attribute",
      "domain_of": [
        "Attribute"
      ],
      "range": "OntologyClass",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "has_qualitative_value",
      "definition_uri": "https://w3id.org/biolink/vocab/has_qualitative_value",
      "description": "connects an attribute to a value",
      "in_subset": [
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "domain": "Attribute",
      "slot_uri": "https://w3id.org/biolink/vocab/has_qualitative_value",
      "owner": "Attribute",
      "domain_of": [
        "Attribute"
      ],
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_quantitative_value",
      "definition_uri": "https://w3id.org/biolink/vocab/has_quantitative_value",
      "exact_mappings": [
        "http://qudt.org/1.1/schema/qudt#quantityValue"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/SNOMED_has_concentration_strength_numerator_value",
        "http://purl.obolibrary.org/obo/SNOMED_has_presentation_strength_denominator_value",
        "http://purl.obolibrary.org/obo/SNOMED_has_presentation_strength_numerator_value"
      ],
      "description": "connects an attribute to a value",
      "in_subset": [
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "domain": "Attribute",
      "slot_uri": "https://w3id.org/biolink/vocab/has_quantitative_value",
      "multivalued": true,
      "inlined": true,
      "owner": "Attribute",
      "domain_of": [
        "Attribute"
      ],
      "range": "QuantityValue",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_numeric_value",
      "definition_uri": "https://w3id.org/biolink/vocab/has_numeric_value",
      "exact_mappings": [
        "http://qudt.org/1.1/schema/qudt#quantityValue"
      ],
      "description": "connects a quantity value to a number",
      "in_subset": [
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "domain": "QuantityValue",
      "slot_uri": "https://w3id.org/biolink/vocab/has_numeric_value",
      "owner": "QuantityValue",
      "domain_of": [
        "QuantityValue"
      ],
      "range": "double",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_unit",
      "definition_uri": "https://w3id.org/biolink/vocab/has_unit",
      "exact_mappings": [
        "http://qudt.org/1.1/schema/qudt#unit",
        "http://purl.obolibrary.org/obo/IAO_0000039"
      ],
      "close_mappings": [
        "http://www.ebi.ac.uk/efo/EFO_0001697",
        "http://purl.obolibrary.org/obo/uo#is_unit_of"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/SNOMED_has_concentration_strength_denominator_unit",
        "http://purl.obolibrary.org/obo/SNOMED_has_concentration_strength_numerator_unit",
        "http://purl.obolibrary.org/obo/SNOMED_has_presentation_strength_denominator_unit",
        "http://purl.obolibrary.org/obo/SNOMED_has_presentation_strength_numerator_unit",
        "http://purl.obolibrary.org/obo/SNOMED_has_unit_of_presentation"
      ],
      "description": "connects a quantity value to a unit",
      "in_subset": [
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "domain": "QuantityValue",
      "slot_uri": "https://w3id.org/biolink/vocab/has_unit",
      "owner": "QuantityValue",
      "domain_of": [
        "QuantityValue"
      ],
      "range": "unit",
      "@type": "SlotDefinition"
    },
    {
      "name": "node_property",
      "definition_uri": "https://w3id.org/biolink/vocab/node_property",
      "description": "A grouping for any property that holds between a node and a value",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/node_property",
      "owner": "node_property",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "id",
      "definition_uri": "https://w3id.org/biolink/vocab/id",
      "exact_mappings": [
        "https://www.alliancegenome.org/primaryId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#ID",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_ID"
      ],
      "description": "A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "slot_uri": "https://w3id.org/biolink/vocab/id",
      "identifier": true,
      "owner": "Entity",
      "domain_of": [
        "Entity"
      ],
      "range": "string",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "iri",
      "definition_uri": "https://w3id.org/biolink/vocab/iri",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P854"
      ],
      "description": "An IRI for an entity. This is determined by the id using expansion rules.",
      "in_subset": [
        "translator_minimal",
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "slot_uri": "https://w3id.org/biolink/vocab/iri",
      "owner": "Entity",
      "domain_of": [
        "Attribute",
        "Entity"
      ],
      "range": "iri_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "type",
      "definition_uri": "https://w3id.org/biolink/vocab/type",
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#type"
      ],
      "exact_mappings": [
        "https://www.alliancegenome.org/soTermId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#type",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Type"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#type",
      "owner": "Entity",
      "domain_of": [
        "Entity"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "category",
      "definition_uri": "https://w3id.org/biolink/vocab/category",
      "description": "Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class.\n * In a neo4j database this MAY correspond to the neo4j label tag.\n * In an RDF database it should be a biolink model class URI.\nThis field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values `biolink:Protein`, `biolink:GeneProduct`, `biolink:MolecularEntity`, ...\nIn an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature `f` may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing}",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "type",
      "domain": "Entity",
      "slot_uri": "https://w3id.org/biolink/vocab/category",
      "multivalued": true,
      "owner": "Entity",
      "domain_of": [
        "Entity"
      ],
      "is_class_field": true,
      "range": "category_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "name",
      "definition_uri": "https://w3id.org/biolink/vocab/name",
      "aliases": [
        "label",
        "display name",
        "title"
      ],
      "mappings": [
        "http://www.w3.org/2000/01/rdf-schema#label"
      ],
      "exact_mappings": [
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#Name",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Name"
      ],
      "narrow_mappings": [
        "http://purl.org/dc/terms/title",
        "https://www.wikidata.org/wiki/Property:P1476"
      ],
      "description": "A human-readable name for an attribute or entity.",
      "in_subset": [
        "translator_minimal",
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "slot_uri": "http://www.w3.org/2000/01/rdf-schema#label",
      "owner": "MacromolecularMachineMixin",
      "domain_of": [
        "Attribute",
        "Entity",
        "MacromolecularMachineMixin"
      ],
      "range": "label_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "source",
      "definition_uri": "https://w3id.org/biolink/vocab/source",
      "description": "a lightweight analog to the association class 'has provider' slot, which is the string name, or the authoritative (i.e. database) namespace, designating the origin of the entity to which the slot belongs.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "slot_uri": "https://w3id.org/biolink/vocab/source",
      "owner": "Entity",
      "domain_of": [
        "Attribute",
        "Entity"
      ],
      "range": "label_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "filler",
      "definition_uri": "https://w3id.org/biolink/vocab/filler",
      "description": "The value in a property-value tuple",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/filler",
      "owner": "filler",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "symbol",
      "definition_uri": "https://w3id.org/biolink/vocab/symbol",
      "exact_mappings": [
        "https://www.alliancegenome.org/symbol",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Symbol"
      ],
      "description": "Symbol for a particular thing",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/symbol",
      "owner": "symbol",
      "domain_of": [
        "Gene"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "synonym",
      "definition_uri": "https://w3id.org/biolink/vocab/synonym",
      "aliases": [
        "alias"
      ],
      "narrow_mappings": [
        "https://www.w3.org/TR/skos-reference/#altLabel",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#Alias",
        "https://www.alliancegenome.org/synonyms",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Synonyms",
        "http://www.geneontology.org/formats/oboInOwl#hasExactSynonym",
        "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym",
        "http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym",
        "http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym",
        "http://www.ebi.ac.uk/ancestro/ancestro_0330",
        "http://purl.obolibrary.org/obo/IAO_0000136",
        "http://purl.bioontology.org/ontology/RXNORM/has_tradename"
      ],
      "description": "Alternate human-readable names for a thing",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/synonym",
      "multivalued": true,
      "owner": "synonym",
      "domain_of": [
        "Gene",
        "GeneProductMixin"
      ],
      "range": "label_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_topic",
      "definition_uri": "https://w3id.org/biolink/vocab/has_topic",
      "aliases": [
        "topic",
        "descriptors"
      ],
      "exact_mappings": [
        "http://xmlns.com/foaf/0.1/topic"
      ],
      "description": "Connects a node to a vocabulary term or ontology class that describes some aspect of the entity. In general specific characterization is preferred. See https://github.com/biolink/biolink-model/issues/238",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_topic",
      "inlined": true,
      "owner": "has_topic",
      "range": "OntologyClass",
      "@type": "SlotDefinition"
    },
    {
      "name": "xref",
      "definition_uri": "https://w3id.org/biolink/vocab/xref",
      "aliases": [
        "dbxref",
        "Dbxref",
        "DbXref"
      ],
      "narrow_mappings": [
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#Dbxref",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Xrefs"
      ],
      "description": "Alternate CURIEs for a thing",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/xref",
      "multivalued": true,
      "owner": "xref",
      "domain_of": [
        "Publication",
        "Gene",
        "GeneProductMixin"
      ],
      "range": "iri_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "full_name",
      "definition_uri": "https://w3id.org/biolink/vocab/full_name",
      "description": "a long-form human readable name for a thing",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/full_name",
      "owner": "full_name",
      "range": "label_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "description",
      "definition_uri": "https://w3id.org/biolink/vocab/description",
      "aliases": [
        "definition"
      ],
      "mappings": [
        "http://purl.org/dc/terms/description"
      ],
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/IAO_0000115",
        "https://www.w3.org/TR/skos-reference/#definitions"
      ],
      "narrow_mappings": [
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#Description"
      ],
      "description": "a human-readable description of an entity",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "slot_uri": "http://purl.org/dc/terms/description",
      "owner": "Entity",
      "domain_of": [
        "Entity"
      ],
      "range": "narrative_text",
      "@type": "SlotDefinition"
    },
    {
      "name": "systematic_synonym",
      "definition_uri": "https://w3id.org/biolink/vocab/systematic_synonym",
      "mappings": [
        "http://purl.obolibrary.org/obo/go#systematic_synonym"
      ],
      "description": "more commonly used for gene symbols in yeast",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "http://purl.obolibrary.org/obo/go#systematic_synonym",
      "multivalued": true,
      "owner": "systematic_synonym",
      "range": "label_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "affiliation",
      "definition_uri": "https://w3id.org/biolink/vocab/affiliation",
      "description": "a professional relationship between one provider (often a person) within another provider (often an organization). Target provider identity should be specified by a CURIE. Providers may have multiple affiliations.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "Agent",
      "slot_uri": "https://w3id.org/biolink/vocab/affiliation",
      "multivalued": true,
      "owner": "Agent",
      "domain_of": [
        "Agent"
      ],
      "range": "uriorcurie",
      "@type": "SlotDefinition"
    },
    {
      "name": "address",
      "definition_uri": "https://w3id.org/biolink/vocab/address",
      "description": "the particulars of the place where someone or an organization is situated.  For now, this slot is a simple text \"blob\" containing all relevant details of the given location for fitness of purpose. For the moment, this \"address\" can include other contact details such as email and phone number(?).",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/address",
      "owner": "Agent",
      "domain_of": [
        "Agent"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "latitude",
      "definition_uri": "https://w3id.org/biolink/vocab/latitude",
      "exact_mappings": [
        "http://www.w3.org/2003/01/geo/wgs84_poslat"
      ],
      "description": "latitude",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/latitude",
      "owner": "GeographicLocation",
      "domain_of": [
        "GeographicLocation"
      ],
      "range": "float",
      "@type": "SlotDefinition"
    },
    {
      "name": "longitude",
      "definition_uri": "https://w3id.org/biolink/vocab/longitude",
      "exact_mappings": [
        "http://www.w3.org/2003/01/geo/wgs84_poslong"
      ],
      "description": "longitude",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/longitude",
      "owner": "GeographicLocation",
      "domain_of": [
        "GeographicLocation"
      ],
      "range": "float",
      "@type": "SlotDefinition"
    },
    {
      "name": "timepoint",
      "definition_uri": "https://w3id.org/biolink/vocab/timepoint",
      "description": "a point in time",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/timepoint",
      "owner": "ExposureEvent",
      "domain_of": [
        "GeographicLocationAtTime",
        "ExposureEvent"
      ],
      "range": "time_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "creation_date",
      "definition_uri": "https://w3id.org/biolink/vocab/creation_date",
      "aliases": [
        "publication date"
      ],
      "exact_mappings": [
        "http://purl.org/dc/terms/createdOn",
        "https://www.wikidata.org/wiki/Property:P577"
      ],
      "description": "date on which an entity was created. This can be applied to nodes or edges",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/creation_date",
      "owner": "InformationContentEntity",
      "domain_of": [
        "InformationContentEntity"
      ],
      "range": "date",
      "@type": "SlotDefinition"
    },
    {
      "name": "update_date",
      "definition_uri": "https://w3id.org/biolink/vocab/update_date",
      "description": "date on which an entity was updated. This can be applied to nodes or edges",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/update_date",
      "owner": "update_date",
      "range": "date",
      "@type": "SlotDefinition"
    },
    {
      "name": "aggregate_statistic",
      "definition_uri": "https://w3id.org/biolink/vocab/aggregate_statistic",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "abstract": true,
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/aggregate_statistic",
      "owner": "aggregate_statistic",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_count",
      "definition_uri": "https://w3id.org/biolink/vocab/has_count",
      "exact_mappings": [
        "http://loinc.org/rdf/has_count"
      ],
      "description": "number of things with a particular property",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "aggregate_statistic",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_count",
      "owner": "FrequencyQuantifier",
      "domain_of": [
        "FrequencyQuantifier"
      ],
      "range": "integer",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_total",
      "definition_uri": "https://w3id.org/biolink/vocab/has_total",
      "description": "total number of things in a particular reference set",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "aggregate_statistic",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_total",
      "owner": "FrequencyQuantifier",
      "domain_of": [
        "FrequencyQuantifier"
      ],
      "range": "integer",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_quotient",
      "definition_uri": "https://w3id.org/biolink/vocab/has_quotient",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "aggregate_statistic",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_quotient",
      "owner": "FrequencyQuantifier",
      "domain_of": [
        "FrequencyQuantifier"
      ],
      "range": "double",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_percentage",
      "definition_uri": "https://w3id.org/biolink/vocab/has_percentage",
      "description": "equivalent to has quotient multiplied by 100",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "aggregate_statistic",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_percentage",
      "owner": "FrequencyQuantifier",
      "domain_of": [
        "FrequencyQuantifier"
      ],
      "range": "double",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_dataset",
      "definition_uri": "https://w3id.org/biolink/vocab/has_dataset",
      "mappings": [
        "http://purl.org/dc/terms/source"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "DatasetVersion",
      "slot_uri": "http://purl.org/dc/terms/source",
      "owner": "DatasetVersion",
      "domain_of": [
        "DatasetVersion"
      ],
      "range": "Dataset",
      "@type": "SlotDefinition"
    },
    {
      "name": "source_web_page",
      "definition_uri": "https://w3id.org/biolink/vocab/source_web_page",
      "broad_mappings": [
        "http://purl.org/dc/terms/source"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "DatasetSummary",
      "slot_uri": "https://w3id.org/biolink/vocab/source_web_page",
      "owner": "DatasetSummary",
      "domain_of": [
        "DatasetSummary"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "source_logo",
      "definition_uri": "https://w3id.org/biolink/vocab/source_logo",
      "mappings": [
        "http://schema.org/logo"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "DatasetSummary",
      "slot_uri": "http://schema.org/logo",
      "owner": "DatasetSummary",
      "domain_of": [
        "DatasetSummary"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "retrieved_on",
      "definition_uri": "https://w3id.org/biolink/vocab/retrieved_on",
      "exact_mappings": [
        "http://purl.org/pav/retrievedOn"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "Dataset",
      "slot_uri": "https://w3id.org/biolink/vocab/retrieved_on",
      "owner": "retrieved_on",
      "range": "date",
      "@type": "SlotDefinition"
    },
    {
      "name": "version_of",
      "definition_uri": "https://w3id.org/biolink/vocab/version_of",
      "exact_mappings": [
        "http://purl.org/dc/terms/isVersionOf"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "DatasetVersion",
      "slot_uri": "https://w3id.org/biolink/vocab/version_of",
      "owner": "version_of",
      "range": "DatasetSummary",
      "@type": "SlotDefinition"
    },
    {
      "name": "version",
      "definition_uri": "https://w3id.org/biolink/vocab/version",
      "broad_mappings": [
        "http://purl.org/pav/version",
        "http://www.w3.org/2002/07/owl#versionInfo"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "Dataset",
      "slot_uri": "https://w3id.org/biolink/vocab/version",
      "owner": "version",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "license",
      "definition_uri": "https://w3id.org/biolink/vocab/license",
      "exact_mappings": [
        "http://purl.org/dc/terms/license"
      ],
      "narrow_mappings": [
        "https://www.wikidata.org/wiki/Property:P275"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "InformationContentEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/license",
      "owner": "InformationContentEntity",
      "domain_of": [
        "InformationContentEntity"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "rights",
      "definition_uri": "https://w3id.org/biolink/vocab/rights",
      "exact_mappings": [
        "http://purl.org/dc/terms/rights"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "InformationContentEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/rights",
      "owner": "InformationContentEntity",
      "domain_of": [
        "InformationContentEntity"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "format",
      "definition_uri": "https://w3id.org/biolink/vocab/format",
      "exact_mappings": [
        "http://purl.org/dc/terms/format",
        "https://www.wikidata.org/wiki/Property:P2701"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "InformationContentEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/format",
      "owner": "InformationContentEntity",
      "domain_of": [
        "InformationContentEntity"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "created_with",
      "definition_uri": "https://w3id.org/biolink/vocab/created_with",
      "exact_mappings": [
        "http://purl.org/pav/createdWith"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "Dataset",
      "slot_uri": "https://w3id.org/biolink/vocab/created_with",
      "owner": "created_with",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "download_url",
      "definition_uri": "https://w3id.org/biolink/vocab/download_url",
      "mappings": [
        "http://www.w3.org/ns/dcat#downloadURL"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "InformationContentEntity",
      "slot_uri": "http://www.w3.org/ns/dcat#downloadURL",
      "owner": "download_url",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "dataset_download_url",
      "definition_uri": "https://w3id.org/biolink/vocab/dataset_download_url",
      "mappings": [
        "http://www.w3.org/ns/dcat#downloadURL"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "Dataset",
      "slot_uri": "http://www.w3.org/ns/dcat#downloadURL",
      "owner": "dataset_download_url",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "distribution_download_url",
      "definition_uri": "https://w3id.org/biolink/vocab/distribution_download_url",
      "exact_mappings": [
        "http://www.w3.org/ns/dcat#downloadURL"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "DatasetDistribution",
      "slot_uri": "https://w3id.org/biolink/vocab/distribution_download_url",
      "owner": "DatasetDistribution",
      "domain_of": [
        "DatasetDistribution"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "ingest_date",
      "definition_uri": "https://w3id.org/biolink/vocab/ingest_date",
      "mappings": [
        "http://purl.org/pav/version"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "DatasetVersion",
      "slot_uri": "http://purl.org/pav/version",
      "owner": "DatasetVersion",
      "domain_of": [
        "DatasetVersion"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_distribution",
      "definition_uri": "https://w3id.org/biolink/vocab/has_distribution",
      "mappings": [
        "http://purl.org/dc/terms/distribution"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "DatasetVersion",
      "slot_uri": "http://purl.org/dc/terms/distribution",
      "owner": "DatasetVersion",
      "domain_of": [
        "DatasetVersion"
      ],
      "range": "DatasetDistribution",
      "@type": "SlotDefinition"
    },
    {
      "name": "published_in",
      "definition_uri": "https://w3id.org/biolink/vocab/published_in",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P1433"
      ],
      "description": "CURIE identifier of a broader publication context within which the publication may be placed, e.g. a specified book or journal.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "values_from": [
        "NLMID",
        "issn",
        "isbn"
      ],
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/published_in",
      "owner": "published_in",
      "domain_of": [
        "BookChapter",
        "Article"
      ],
      "range": "uriorcurie",
      "@type": "SlotDefinition"
    },
    {
      "name": "iso_abbreviation",
      "definition_uri": "https://w3id.org/biolink/vocab/iso_abbreviation",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P1160"
      ],
      "description": "Standard abbreviation for periodicals in the International Organization for Standardization (ISO) 4 system See https://www.issn.org/services/online-services/access-to-the-ltwa/. If the 'published in' property is set, then the iso abbreviation pertains to the broader publication context (the journal) within which the given publication node is embedded, not the publication itself.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/iso_abbreviation",
      "owner": "iso_abbreviation",
      "domain_of": [
        "Serial",
        "Article"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "authors",
      "definition_uri": "https://w3id.org/biolink/vocab/authors",
      "description": "connects an publication to the list of authors who contributed to the publication. This property should be a comma-delimited list of author names. It is recommended that an author's name be formatted as \"surname, firstname initial.\".   Note that this property is a node annotation expressing the citation list of authorship which might typically otherwise be more completely documented in biolink:PublicationToProviderAssociation defined edges which point to full details about an author and possibly, some qualifiers which clarify the specific status of a given author in the publication.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "singular_name": "author",
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/authors",
      "multivalued": true,
      "owner": "Publication",
      "domain_of": [
        "Publication"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "volume",
      "definition_uri": "https://w3id.org/biolink/vocab/volume",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P478"
      ],
      "description": "volume of a book or music release in a collection/series or a published collection of journal issues in a serial publication",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/volume",
      "owner": "volume",
      "domain_of": [
        "BookChapter",
        "Serial",
        "Article"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "chapter",
      "definition_uri": "https://w3id.org/biolink/vocab/chapter",
      "exact_mappings": [
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      ],
      "description": "chapter of a book",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "BookChapter",
      "slot_uri": "https://w3id.org/biolink/vocab/chapter",
      "owner": "BookChapter",
      "domain_of": [
        "BookChapter"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "issue",
      "definition_uri": "https://w3id.org/biolink/vocab/issue",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P433"
      ],
      "description": "issue of a newspaper, a scientific journal or magazine for reference purpose",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/issue",
      "owner": "issue",
      "domain_of": [
        "Serial",
        "Article"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "pages",
      "definition_uri": "https://w3id.org/biolink/vocab/pages",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P304"
      ],
      "description": "page number of source referenced for statement or publication",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/pages",
      "multivalued": true,
      "owner": "Publication",
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        "Publication"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "summary",
      "definition_uri": "https://w3id.org/biolink/vocab/summary",
      "aliases": [
        "abstract"
      ],
      "exact_mappings": [
        "http://purl.org/dc/terms/abstract",
        "https://www.wikidata.org/wiki/Q333291"
      ],
      "description": "executive  summary of a publication",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/summary",
      "owner": "Publication",
      "domain_of": [
        "Publication"
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      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "keywords",
      "definition_uri": "https://w3id.org/biolink/vocab/keywords",
      "description": "keywords tagging a publication",
      "from_schema": "https://w3id.org/biolink/biolink-model",
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      "slot_uri": "https://w3id.org/biolink/vocab/keywords",
      "multivalued": true,
      "owner": "Publication",
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        "Publication"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "mesh_terms",
      "definition_uri": "https://w3id.org/biolink/vocab/mesh_terms",
      "description": "mesh terms tagging a publication",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "values_from": [
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      ],
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/mesh_terms",
      "multivalued": true,
      "owner": "Publication",
      "domain_of": [
        "Publication"
      ],
      "range": "uriorcurie",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_biological_sequence",
      "definition_uri": "https://w3id.org/biolink/vocab/has_biological_sequence",
      "description": "connects a genomic feature to its sequence",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_biological_sequence",
      "owner": "GenomicEntity",
      "domain_of": [
        "GenomicEntity"
      ],
      "range": "biological_sequence",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_gene_or_gene_product",
      "definition_uri": "https://w3id.org/biolink/vocab/has_gene_or_gene_product",
      "description": "connects an entity with one or more gene or gene products",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
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      "slot_uri": "https://w3id.org/biolink/vocab/has_gene_or_gene_product",
      "multivalued": true,
      "owner": "GeneGroupingMixin",
      "domain_of": [
        "GeneGroupingMixin"
      ],
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_gene",
      "definition_uri": "https://w3id.org/biolink/vocab/has_gene",
      "description": "connects an entity associated with one or more genes",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_gene_or_gene_product",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_gene",
      "multivalued": true,
      "owner": "SequenceVariant",
      "domain_of": [
        "SequenceVariant"
      ],
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_zygosity",
      "definition_uri": "https://w3id.org/biolink/vocab/has_zygosity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "GenomicEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/has_zygosity",
      "inlined": true,
      "owner": "has_zygosity",
      "domain_of": [
        "Genotype"
      ],
      "range": "Zygosity",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_chemical_formula",
      "definition_uri": "https://w3id.org/biolink/vocab/has_chemical_formula",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P274"
      ],
      "description": "description of chemical compound based on element symbols",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_chemical_formula",
      "owner": "has_chemical_formula",
      "range": "chemical_formula_value",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_metabolite",
      "definition_uri": "https://w3id.org/biolink/vocab/is_metabolite",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/CHEBI_25212"
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      "description": "indicates whether a chemical substance is a metabolite",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "ChemicalSubstance",
      "slot_uri": "https://w3id.org/biolink/vocab/is_metabolite",
      "owner": "ChemicalSubstance",
      "domain_of": [
        "ChemicalSubstance"
      ],
      "range": "boolean",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_constituent",
      "definition_uri": "https://w3id.org/biolink/vocab/has_constituent",
      "description": "one or more chemical substances within a mixture",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "node_property",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_constituent",
      "multivalued": true,
      "owner": "Mixture",
      "domain_of": [
        "Mixture"
      ],
      "range": "ChemicalSubstance",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_drug",
      "definition_uri": "https://w3id.org/biolink/vocab/has_drug",
      "description": "connects an entity to one or more drugs",
      "from_schema": "https://w3id.org/biolink/biolink-model",
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      "slot_uri": "https://w3id.org/biolink/vocab/has_drug",
      "multivalued": true,
      "owner": "Treatment",
      "domain_of": [
        "Treatment"
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      "range": "Drug",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_device",
      "definition_uri": "https://w3id.org/biolink/vocab/has_device",
      "description": "connects an entity to one or more (medical) devices",
      "from_schema": "https://w3id.org/biolink/biolink-model",
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      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_device",
      "multivalued": true,
      "owner": "Treatment",
      "domain_of": [
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      ],
      "range": "Device",
      "@type": "SlotDefinition"
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    {
      "name": "has_procedure",
      "definition_uri": "https://w3id.org/biolink/vocab/has_procedure",
      "description": "connects an entity to one or more (medical) procedures",
      "from_schema": "https://w3id.org/biolink/biolink-model",
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      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_procedure",
      "multivalued": true,
      "owner": "Treatment",
      "domain_of": [
        "Treatment"
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      "range": "Procedure",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_receptor",
      "definition_uri": "https://w3id.org/biolink/vocab/has_receptor",
      "exact_mappings": [
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      ],
      "description": "the organism or organism part being exposed",
      "from_schema": "https://w3id.org/biolink/biolink-model",
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      "slot_uri": "https://w3id.org/biolink/vocab/has_receptor",
      "owner": "has_receptor",
      "range": "OrganismalEntity",
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      "name": "has_stressor",
      "definition_uri": "https://w3id.org/biolink/vocab/has_stressor",
      "aliases": [
        "has stimulus"
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      "exact_mappings": [
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      "description": "the process or entity that the receptor is being exposed to",
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      "owner": "has_stressor",
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      "name": "has_route",
      "definition_uri": "https://w3id.org/biolink/vocab/has_route",
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      "narrow_mappings": [
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      "description": "the process that results in the stressor coming into direct contact with the receptor",
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      "range": "PopulationOfIndividualOrganisms",
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      "range": "time_type",
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        "http://www.ebi.ac.uk/efo/EFO_0006351",
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        "http://purl.bioontology.org/ontology/HCPCS/mapped_to",
        "http://identifiers.org/hmdb/disease",
        "http://identifiers.org/hmdb/has_protein_association",
        "http://purl.obolibrary.org/obo/IAO_0000136",
        "http://loinc.org/rdf/has_answer",
        "http://loinc.org/rdf/has_challenge",
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        "http://identifiers.org/mesh/mapped_to",
        "http://purl.obolibrary.org/obo/MONDO_disease_shares_features_of",
        "http://purl.obolibrary.org/obo/NCIT_disease_may_have_associated_disease",
        "http://purl.obolibrary.org/obo/NCIT_human_disease_maps_to_eo_disease",
        "http://purl.obolibrary.org/obo/NCIT_is_abnormal_cell_of_disease",
        "http://purl.obolibrary.org/obo/NCIT_is_related_to_endogenous_product",
        "http://purl.obolibrary.org/obo/core#connected_to",
        "http://purl.obolibrary.org/obo/core#innervated_by",
        "http://purl.obolibrary.org/obo/envo#has_increased_levels_of",
        "http://purl.obolibrary.org/obo/has_role",
        "http://purl.obolibrary.org/obo/nbo#is_about",
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        "http://purl.obolibrary.org/obo/pato#has_cross_section",
        "http://purl.obolibrary.org/obo/pato#has_relative_magnitude",
        "http://purl.obolibrary.org/obo/pato#increased_in_magnitude_relative_to",
        "http://purl.obolibrary.org/obo/pato#reciprocal_of",
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        "http://purl.obolibrary.org/obo/RO_0002150",
        "http://purl.obolibrary.org/obo/RO_0002159",
        "http://purl.obolibrary.org/obo/RO_0002176",
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        "http://purl.obolibrary.org/obo/RO_0002179",
        "http://purl.obolibrary.org/obo/RO_0002314",
        "http://purl.obolibrary.org/obo/RO_0002322",
        "http://purl.obolibrary.org/obo/RO_0002328",
        "http://purl.obolibrary.org/obo/RO_0002332",
        "http://purl.obolibrary.org/obo/RO_0002338",
        "http://purl.obolibrary.org/obo/RO_0002339",
        "http://purl.obolibrary.org/obo/RO_0002341",
        "http://purl.obolibrary.org/obo/RO_0002342",
        "http://purl.obolibrary.org/obo/RO_0002344",
        "http://purl.obolibrary.org/obo/RO_0002348",
        "http://purl.obolibrary.org/obo/RO_0002349",
        "http://purl.obolibrary.org/obo/RO_0002356",
        "http://purl.obolibrary.org/obo/RO_0002371",
        "http://purl.obolibrary.org/obo/RO_0002372",
        "http://purl.obolibrary.org/obo/RO_0002373",
        "http://purl.obolibrary.org/obo/RO_0002374",
        "http://purl.obolibrary.org/obo/RO_0002385",
        "http://purl.obolibrary.org/obo/RO_0002387",
        "http://purl.obolibrary.org/obo/RO_0002451",
        "http://purl.obolibrary.org/obo/RO_0002494",
        "http://purl.obolibrary.org/obo/RO_0002495",
        "http://purl.obolibrary.org/obo/RO_0002568",
        "http://purl.obolibrary.org/obo/RO_0002573",
        "http://purl.obolibrary.org/obo/RO_0004026",
        "http://purl.obolibrary.org/obo/RO_0004027",
        "http://purl.obolibrary.org/obo/RO_0009001",
        "http://purl.obolibrary.org/obo/RO_0009004",
        "http://kg1endpoint.rtx.ai/functionally_related_to",
        "http://purl.bioontology.org/ontology/RXNORM/has_form",
        "http://purl.bioontology.org/ontology/RXNORM/reformulated_to",
        "http://purl.obolibrary.org/obo/SNOMED_has_associated_morphology",
        "http://purl.obolibrary.org/obo/SNOMED_has_associated_procedure",
        "http://purl.obolibrary.org/obo/SNOMED_has_direct_morphology",
        "http://purl.obolibrary.org/obo/SNOMED_has_disposition",
        "http://purl.obolibrary.org/obo/SNOMED_has_indirect_morphology",
        "http://purl.obolibrary.org/obo/SNOMED_has_modification",
        "http://purl.obolibrary.org/obo/SNOMED_has_procedure_morphology",
        "http://purl.obolibrary.org/obo/SNOMED_has_specimen_source_morphology",
        "http://purl.obolibrary.org/obo/SNOMED_inheres_in",
        "http://purl.obolibrary.org/obo/SNOMED_is_interpreted_by",
        "http://purl.obolibrary.org/obo/SNOMED_relative_to_part_of",
        "http://purl.obolibrary.org/obo/UBERON_synapsed_by",
        "http://identifiers.org/umls/RO",
        "http://identifiers.org/umls/RQ",
        "http://identifiers.org/umls/class_code_classified_by",
        "http://identifiers.org/umls/exhibited_by",
        "http://identifiers.org/umls/has_context_binding",
        "http://identifiers.org/umls/has_form",
        "http://identifiers.org/umls/has_mapping_qualifier",
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        "http://identifiers.org/umls/mapped_to",
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      "broad_mappings": [
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      "description": "A relationship that is asserted between two named things",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/related_to",
      "multivalued": true,
      "inherited": true,
      "owner": "related_to",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "superclass_of",
      "definition_uri": "https://w3id.org/biolink/vocab/superclass_of",
      "exact_mappings": [
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        "https://www.ebi.ac.uk/chembl/mechanism/inspect/superset_of",
        "http://purl.obolibrary.org/obo/GO_inverse_isa",
        "http://identifiers.org/mesh/inverse_isa",
        "http://purl.bioontology.org/ontology/RXNORM/inverse_isa",
        "https://www.nlm.nih.gov/research/umls/sourcereleasedocs/current/VANDF/inverse_isa"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_cdrh_parent_of",
        "http://purl.obolibrary.org/obo/NCIT_ctcae_5_parent_of",
        "http://purl.obolibrary.org/obo/NCIT_subset_includes_concept",
        "http://purl.obolibrary.org/obo/OMIM_has_manifestation",
        "http://purl.obolibrary.org/obo/SNOMED_has_basic_dose_form",
        "http://identifiers.org/umls/RB"
      ],
      "description": "holds between two classes where the domain class is a super class of the range class",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "OntologyClass",
      "slot_uri": "https://w3id.org/biolink/vocab/superclass_of",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "superclass_of",
      "inverse": "subclass_of",
      "range": "OntologyClass",
      "@type": "SlotDefinition"
    },
    {
      "name": "subclass_of",
      "definition_uri": "https://w3id.org/biolink/vocab/subclass_of",
      "exact_mappings": [
        "http://www.w3.org/2000/01/rdf-schema#subClassOf",
        "https://skr3.nlm.nih.gov/SemMedDBIS_A",
        "https://skr3.nlm.nih.gov/SemMedDBisa",
        "https://www.wikidata.org/wiki/Property:P279",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/subset_of",
        "http://purl.obolibrary.org/obo/GO_isa",
        "http://identifiers.org/mesh/isa",
        "http://kg1endpoint.rtx.ai/subclass_of",
        "http://purl.bioontology.org/ontology/RXNORM/isa",
        "https://www.nlm.nih.gov/research/umls/sourcereleasedocs/current/VANDF/isa"
      ],
      "close_mappings": [
        "http://loinc.org/rdf/class_of",
        "http://loinc.org/rdf/has_class"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/CHEBI_has_parent_hydride",
        "http://loinc.org/rdf/has_archetype",
        "http://loinc.org/rdf/has_parent_group",
        "http://loinc.org/rdf/is_presence_guidance_for",
        "http://purl.obolibrary.org/obo/NCIT_gene_product_has_chemical_classification",
        "http://purl.obolibrary.org/obo/NCIT_R36",
        "http://purl.obolibrary.org/obo/NCIT_R42",
        "http://purl.obolibrary.org/obo/NCIT_A16",
        "http://purl.obolibrary.org/obo/NCIT_A11",
        "http://purl.obolibrary.org/obo/NCIT_A14",
        "http://purl.obolibrary.org/obo/NCIT_A3",
        "http://purl.bioontology.org/ontology/NDDF/has_dose_form",
        "http://purl.obolibrary.org/obo/intersection_of",
        "http://purl.bioontology.org/ontology/RXNORM/has_dose_form",
        "http://purl.bioontology.org/ontology/RXNORM/has_doseformgroup",
        "http://purl.obolibrary.org/obo/SNOMED_entire_anatomy_structure_of",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form",
        "http://www.w3.org/2000/01/rdf-schema#subPropertyOf"
      ],
      "description": "holds between two classes where the domain class is a specialization of the range class",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "OntologyClass",
      "slot_uri": "https://w3id.org/biolink/vocab/subclass_of",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "subclass_of",
      "inverse": "superclass_of",
      "range": "OntologyClass",
      "@type": "SlotDefinition"
    },
    {
      "name": "same_as",
      "definition_uri": "https://w3id.org/biolink/vocab/same_as",
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#sameAs",
        "https://www.w3.org/TR/skos-reference/#exactMatch",
        "https://www.wikidata.org/wiki/Property:P2888",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/equivalent_to",
        "http://purl.obolibrary.org/obo/MONDO_equivalentTo"
      ],
      "close_mappings": [
        "http://www.w3.org/2002/07/owl#equivalentClass"
      ],
      "narrow_mappings": [
        "http://identifiers.org/drugbank/external-identifier"
      ],
      "description": "holds between two entities that are considered equivalent to each other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "exact_match",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/same_as",
      "multivalued": true,
      "inherited": true,
      "owner": "same_as",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "close_match",
      "definition_uri": "https://w3id.org/biolink/vocab/close_match",
      "exact_mappings": [
        "https://www.w3.org/TR/skos-reference/#closeMatch",
        "https://skr3.nlm.nih.gov/SemMedDBSAME_AS",
        "https://skr3.nlm.nih.gov/SemMedDBsame_as"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/CHEBI_is_enantiomer_of",
        "http://purl.obolibrary.org/obo/CHEBI_is_tautomer_of",
        "http://identifiers.org/meddra/classified_as",
        "http://purl.obolibrary.org/obo/xref",
        "http://www.geneontology.org/formats/oboInOWL#xref",
        "http://purl.bioontology.org/ontology/RXNORM/has_quantified_form",
        "http://identifiers.org/umls/SY"
      ],
      "description": "a list of terms from different schemas or terminology systems that have a semantically similar but not strictly equivalent, broader, or narrower meaning. Such terms often describe the same general concept from different ontological perspectives (e.g. drug as a type of chemical entity versus drug as a type of role borne by a chemical entity).",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/close_match",
      "multivalued": true,
      "inherited": true,
      "owner": "close_match",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "exact_match",
      "definition_uri": "https://w3id.org/biolink/vocab/exact_match",
      "exact_mappings": [
        "https://www.w3.org/TR/skos-reference/#exactMatch",
        "https://www.wikidata.org/wiki/Q39893449",
        "https://www.wikidata.org/wiki/P2888"
      ],
      "description": "holds between two entities that have strictly equivalent meanings, with a high degree of confidence",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "close_match",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/exact_match",
      "multivalued": true,
      "inherited": true,
      "owner": "exact_match",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "broad_match",
      "definition_uri": "https://w3id.org/biolink/vocab/broad_match",
      "exact_mappings": [
        "https://www.w3.org/TR/skos-reference/#broadMatch",
        "https://www.wikidata.org/wiki/Q39894595"
      ],
      "description": "a list of terms from different schemas or terminology systems that have a broader, more general meaning. Broader terms are typically shown as parents in a hierarchy or tree.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/broad_match",
      "multivalued": true,
      "inherited": true,
      "owner": "broad_match",
      "inverse": "narrow_match",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "narrow_match",
      "definition_uri": "https://w3id.org/biolink/vocab/narrow_match",
      "exact_mappings": [
        "https://www.w3.org/TR/skos-reference/#narrowMatch",
        "https://www.wikidata.org/wiki/Q39893967"
      ],
      "description": "a list of terms from different schemas or terminology systems that have a narrower, more specific meaning. Narrower terms are typically shown as children in a hierarchy or tree.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/narrow_match",
      "multivalued": true,
      "inherited": true,
      "owner": "narrow_match",
      "inverse": "broad_match",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "opposite_of",
      "definition_uri": "https://w3id.org/biolink/vocab/opposite_of",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002604"
      ],
      "description": "x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x). (This description is from RO. Needs to be rephrased).",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "see_also": [
        "https://doi.org/10.1101/108977",
        "https://github.com/biolink/biolink-model/issues/657"
      ],
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/opposite_of",
      "multivalued": true,
      "inherited": true,
      "owner": "opposite_of",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "contributor",
      "definition_uri": "https://w3id.org/biolink/vocab/contributor",
      "exact_mappings": [
        "http://purl.org/dc/terms/contributor"
      ],
      "comments": [
        "This is a grouping for predicates relating entities to their associated contributors realizing them"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "abstract": true,
      "domain": "InformationContentEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/contributor",
      "multivalued": true,
      "inherited": true,
      "owner": "contributor",
      "range": "Agent",
      "@type": "SlotDefinition"
    },
    {
      "name": "provider",
      "definition_uri": "https://w3id.org/biolink/vocab/provider",
      "description": "person, group, organization or project that provides a piece of information (e.g. a knowledge association).",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "contributor",
      "domain": "InformationContentEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/provider",
      "multivalued": true,
      "inherited": true,
      "owner": "provider",
      "range": "Agent",
      "@type": "SlotDefinition"
    },
    {
      "name": "publisher",
      "definition_uri": "https://w3id.org/biolink/vocab/publisher",
      "exact_mappings": [
        "http://purl.org/dc/terms/publisher",
        "https://www.wikidata.org/wiki/Property:P123"
      ],
      "description": "organization or person responsible for publishing books, periodicals, podcasts, games or software. Note that in the case of publications which have a containing \"published in\" node property, the publisher association may not be attached directly to the embedded child publication, but only made in between the parent's publication node and the publisher agent of the encompassing publication (e.g. only from the Journal referenced by the 'published_in' property of an journal article Publication node).",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "contributor",
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/publisher",
      "multivalued": true,
      "inherited": true,
      "owner": "publisher",
      "range": "Agent",
      "@type": "SlotDefinition"
    },
    {
      "name": "editor",
      "definition_uri": "https://w3id.org/biolink/vocab/editor",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P98"
      ],
      "description": "editor of a compiled work such as a book or a periodical (newspaper or an academic journal). Note that in the case of publications which have a containing \"published in\" node property, the editor association may not be attached directly to the embedded child publication, but only made in between the parent's publication node and the editorial agent of the encompassing publication (e.g. only from the Book referenced by the 'published_in' property of a book chapter Publication node).",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "contributor",
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/editor",
      "multivalued": true,
      "inherited": true,
      "owner": "editor",
      "range": "Agent",
      "@type": "SlotDefinition"
    },
    {
      "name": "author",
      "definition_uri": "https://w3id.org/biolink/vocab/author",
      "exact_mappings": [
        "http://purl.org/dc/terms/creator",
        "https://www.wikidata.org/wiki/Property:P50"
      ],
      "description": "an instance of one (co-)creator primarily responsible for a written work",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "contributor",
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/author",
      "multivalued": true,
      "inherited": true,
      "owner": "author",
      "range": "Agent",
      "@type": "SlotDefinition"
    },
    {
      "name": "interacts_with",
      "definition_uri": "https://w3id.org/biolink/vocab/interacts_with",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002434"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002103",
        "http://purl.obolibrary.org/obo/RO_0002120",
        "http://purl.obolibrary.org/obo/RO_0002130",
        "https://skr3.nlm.nih.gov/SemMedDBcomplicates"
      ],
      "description": "holds between any two entities that directly or indirectly interact with each other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/interacts_with",
      "multivalued": true,
      "inherited": true,
      "owner": "interacts_with",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "physically_interacts_with",
      "definition_uri": "https://w3id.org/biolink/vocab/physically_interacts_with",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P129",
        "http://kg1endpoint.rtx.ai/physically_interacts_with"
      ],
      "close_mappings": [
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/binding_agent",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/chelating_agent",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/cross-linking_agent",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/oxidative_enzyme",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/sequestering_agent",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/substrate",
        "http://identifiers.org/drugbank/target"
      ],
      "narrow_mappings": [
        "https://skr3.nlm.nih.gov/SemMedDBINTERACTS_WITH",
        "https://skr3.nlm.nih.gov/SemMedDBinteracts_with",
        "http://identifiers.org/drugbank/drug-interaction",
        "http://purl.obolibrary.org/obo/FMA_adheres_to",
        "http://purl.obolibrary.org/obo/NCIT_A7",
        "http://purl.obolibrary.org/obo/PR_non-covalently_bound_to"
      ],
      "description": "holds between two entities that make physical contact as part of some interaction",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "interacts_with",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/physically_interacts_with",
      "multivalued": true,
      "inherited": true,
      "owner": "physically_interacts_with",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "molecularly_interacts_with",
      "definition_uri": "https://w3id.org/biolink/vocab/molecularly_interacts_with",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002436",
        "http://translator.ncats.nih.gov/CTD_molecularly_interacts_with",
        "http://kg1endpoint.rtx.ai/targets"
      ],
      "related_mappings": [
        "https://www.dgidb.org/interaction_typesantibody"
      ],
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "physically_interacts_with",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/molecularly_interacts_with",
      "multivalued": true,
      "inherited": true,
      "owner": "molecularly_interacts_with",
      "symmetric": true,
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "genetically_interacts_with",
      "definition_uri": "https://w3id.org/biolink/vocab/genetically_interacts_with",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002435"
      ],
      "description": "holds between two genes whose phenotypic effects are dependent on each other in some way - such that their combined phenotypic effects are the result of some interaction between the activity of their gene products. Examples include epistasis and synthetic lethality.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "interacts_with",
      "domain": "Gene",
      "slot_uri": "https://w3id.org/biolink/vocab/genetically_interacts_with",
      "multivalued": true,
      "inherited": true,
      "owner": "genetically_interacts_with",
      "symmetric": true,
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "affects",
      "definition_uri": "https://w3id.org/biolink/vocab/affects",
      "exact_mappings": [
        "https://skr3.nlm.nih.gov/SemMedDBAFFECTS",
        "https://skr3.nlm.nih.gov/SemMedDBaffects",
        "https://www.dgidb.org/interaction_typesaffects",
        "http://kg1endpoint.rtx.ai/affects"
      ],
      "related_mappings": [
        "http://identifiers.org/drugbank/pathway"
      ],
      "narrow_mappings": [
        "https://skr3.nlm.nih.gov/SemMedDBadministered_to",
        "http://translator.ncats.nih.gov/CTD_prediction_hypothesis",
        "http://purl.obolibrary.org/obo/GOREL_0001006",
        "http://translator.ncats.nih.gov/CTD_inferred",
        "http://purl.obolibrary.org/obo/UPHENO_0000001",
        "http://purl.obolibrary.org/obo/RO_0002263",
        "http://purl.obolibrary.org/obo/RO_0002264",
        "http://purl.obolibrary.org/obo/NCIT_R158",
        "http://purl.obolibrary.org/obo/NCIT_R160",
        "http://purl.obolibrary.org/obo/NCIT_R30",
        "http://purl.obolibrary.org/obo/NCIT_R150",
        "http://purl.obolibrary.org/obo/NCIT_R72",
        "http://purl.obolibrary.org/obo/NCIT_R146",
        "http://purl.obolibrary.org/obo/NCIT_R124",
        "http://purl.obolibrary.org/obo/NCIT_R173",
        "http://purl.obolibrary.org/obo/NCIT_R100",
        "http://purl.obolibrary.org/obo/NCIT_R102",
        "http://purl.obolibrary.org/obo/NCIT_R101",
        "http://purl.obolibrary.org/obo/NCIT_R113",
        "http://purl.obolibrary.org/obo/NCIT_R23",
        "http://purl.obolibrary.org/obo/NCIT_R25",
        "http://purl.obolibrary.org/obo/NCIT_gene_mapped_to_disease",
        "http://purl.obolibrary.org/obo/NCIT_R133",
        "http://purl.obolibrary.org/obo/RO_0002343",
        "http://purl.obolibrary.org/obo/RO_0002355",
        "http://purl.obolibrary.org/obo/RO_0002591",
        "http://purl.obolibrary.org/obo/RO_0002592",
        "http://purl.obolibrary.org/obo/RO_0012003",
        "http://purl.obolibrary.org/obo/SNOMED_has_pathological_process"
      ],
      "description": "describes an entity that has a direct affect on the state or quality of another existing entity. Use of the 'affects' predicate implies that the affected entity already exists, unlike predicates such as 'affects risk for' and 'prevents, where the outcome is something that may or may not come to be.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/affects",
      "multivalued": true,
      "inherited": true,
      "owner": "affects",
      "inverse": "affected_by",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "affected_by",
      "definition_uri": "https://w3id.org/biolink/vocab/affected_by",
      "description": "describes an entity of which the state or quality is affected by another existing entity.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/affected_by",
      "multivalued": true,
      "inherited": true,
      "owner": "affected_by",
      "inverse": "affects",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "chemical_role_mixin",
      "definition_uri": "https://w3id.org/biolink/vocab/chemical_role_mixin",
      "exact_mappings": [
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        "http://translator.ncats.nih.gov/CTD_affects_prenylation",
        "http://translator.ncats.nih.gov/CTD_affects_methylation",
        "http://translator.ncats.nih.gov/CTD_affects_nitrosation",
        "http://translator.ncats.nih.gov/CTD_affects_nucleotidylation",
        "http://translator.ncats.nih.gov/CTD_affects_phosphorylation",
        "http://translator.ncats.nih.gov/CTD_affects_ribosylation",
        "http://translator.ncats.nih.gov/CTD_affects_ADP-ribosylation",
        "http://translator.ncats.nih.gov/CTD_affects_sulfation",
        "http://translator.ncats.nih.gov/CTD_affects_sumoylation",
        "http://translator.ncats.nih.gov/CTD_affects_ubiquitination",
        "http://translator.ncats.nih.gov/CTD_affects_oxidation",
        "http://translator.ncats.nih.gov/CTD_affects_reduction",
        "http://translator.ncats.nih.gov/CTD_affects_carboxylation"
      ],
      "description": "holds between two molecular entities where the action or effect of one leads changes in the molecular modification(s) of the other (e.g. via post-translational modifications of proteins such as the addition of phosphoryl group, or via redox reaction that adds or subtracts electrons)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/affects_molecular_modification_of",
      "multivalued": true,
      "inherited": true,
      "owner": "affects_molecular_modification_of",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "increases_molecular_modification_of",
      "definition_uri": "https://w3id.org/biolink/vocab/increases_molecular_modification_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_increases_molecular_modification_of"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/CTD_increases_acetylation",
        "http://translator.ncats.nih.gov/CTD_increases_acylation",
        "http://translator.ncats.nih.gov/CTD_increases_alkylation",
        "http://translator.ncats.nih.gov/CTD_increases_amination",
        "http://translator.ncats.nih.gov/CTD_increases_carbamoylation",
        "http://translator.ncats.nih.gov/CTD_increases_ethylation",
        "http://translator.ncats.nih.gov/CTD_increases_glutathionylation",
        "http://translator.ncats.nih.gov/CTD_increases_glycation",
        "http://translator.ncats.nih.gov/CTD_increases_glycosylation",
        "http://translator.ncats.nih.gov/CTD_increases_glucuronidation",
        "http://translator.ncats.nih.gov/CTD_increases_N-linked_glycosylation",
        "http://translator.ncats.nih.gov/CTD_increases_O-linked_glycosylation",
        "http://translator.ncats.nih.gov/CTD_increases_hydroxylation",
        "http://translator.ncats.nih.gov/CTD_increases_lipidation",
        "http://translator.ncats.nih.gov/CTD_increases_farnesylation",
        "http://translator.ncats.nih.gov/CTD_increases_geranoylation",
        "http://translator.ncats.nih.gov/CTD_increases_myristoylation",
        "http://translator.ncats.nih.gov/CTD_increases_palmitoylation",
        "http://translator.ncats.nih.gov/CTD_increases_prenylation",
        "http://translator.ncats.nih.gov/CTD_increases_methylation",
        "http://translator.ncats.nih.gov/CTD_increases_nitrosation",
        "http://translator.ncats.nih.gov/CTD_increases_nucleotidylation",
        "http://translator.ncats.nih.gov/CTD_increases_phosphorylation",
        "http://translator.ncats.nih.gov/CTD_increases_ribosylation",
        "http://translator.ncats.nih.gov/CTD_increases_ADP-ribosylation",
        "http://translator.ncats.nih.gov/CTD_increases_sulfation",
        "http://translator.ncats.nih.gov/CTD_increases_sumoylation",
        "http://translator.ncats.nih.gov/CTD_increases_ubiquitination",
        "http://translator.ncats.nih.gov/CTD_increases_oxidation",
        "http://translator.ncats.nih.gov/CTD_increases_reduction",
        "http://translator.ncats.nih.gov/CTD_increases_carboxylation",
        "http://translator.renci.org/GAMMA_acetylation",
        "http://translator.renci.org/GAMMA_oxidizer"
      ],
      "description": "holds between two molecular entities where the action or effect of one leads to increased molecular modification(s) of the other (e.g. via post-translational modifications of proteins such as the addition of phosphoryl group, or via redox reaction that adds or subtracts electrons)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_molecular_modification_of",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/increases_molecular_modification_of",
      "multivalued": true,
      "inherited": true,
      "owner": "increases_molecular_modification_of",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "decreases_molecular_modification_of",
      "definition_uri": "https://w3id.org/biolink/vocab/decreases_molecular_modification_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_molecular_modification_of"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_acetylation",
        "http://translator.ncats.nih.gov/CTD_decreases_acylation",
        "http://translator.ncats.nih.gov/CTD_decreases_alkylation",
        "http://translator.ncats.nih.gov/CTD_decreases_amination",
        "http://translator.ncats.nih.gov/CTD_decreases_carbamoylation",
        "http://translator.ncats.nih.gov/CTD_decreases_ethylation",
        "http://translator.ncats.nih.gov/CTD_decreases_glutathionylation",
        "http://translator.ncats.nih.gov/CTD_decreases_glycation",
        "http://translator.ncats.nih.gov/CTD_decreases_glycosylation",
        "http://translator.ncats.nih.gov/CTD_decreases_glucuronidation",
        "http://translator.ncats.nih.gov/CTD_decreases_N-linked_glycosylation",
        "http://translator.ncats.nih.gov/CTD_decreases_O-linked_glycosylation",
        "http://translator.ncats.nih.gov/CTD_decreases_hydroxylation",
        "http://translator.ncats.nih.gov/CTD_decreases_lipidation",
        "http://translator.ncats.nih.gov/CTD_decreases_farnesylation",
        "http://translator.ncats.nih.gov/CTD_decreases_geranoylation",
        "http://translator.ncats.nih.gov/CTD_decreases_myristoylation",
        "http://translator.ncats.nih.gov/CTD_decreases_palmitoylation",
        "http://translator.ncats.nih.gov/CTD_decreases_prenylation",
        "http://translator.ncats.nih.gov/CTD_decreases_methylation",
        "http://translator.ncats.nih.gov/CTD_decreases_nitrosation",
        "http://translator.ncats.nih.gov/CTD_decreases_nucleotidylation",
        "http://translator.ncats.nih.gov/CTD_decreases_phosphorylation",
        "http://translator.ncats.nih.gov/CTD_decreases_ribosylation",
        "http://translator.ncats.nih.gov/CTD_decreases_ADP-ribosylation",
        "http://translator.ncats.nih.gov/CTD_decreases_sulfation",
        "http://translator.ncats.nih.gov/CTD_decreases_sumoylation",
        "http://translator.ncats.nih.gov/CTD_decreases_ubiquitination",
        "http://translator.ncats.nih.gov/CTD_decreases_oxidation",
        "http://translator.ncats.nih.gov/CTD_decreases_reduction",
        "http://translator.ncats.nih.gov/CTD_decreases_carboxylation",
        "http://translator.renci.org/GAMMA_deoxidizer"
      ],
      "description": "holds between two molecular entities where the action or effect of one leads to decreased molecular modification(s) of the other (e.g. via post-translational modifications of proteins such as the addition of phosphoryl group, or via redox reaction that adds or subtracts electrons)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_molecular_modification_of",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/decreases_molecular_modification_of",
      "multivalued": true,
      "inherited": true,
      "owner": "decreases_molecular_modification_of",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "affects_synthesis_of",
      "definition_uri": "https://w3id.org/biolink/vocab/affects_synthesis_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_affects_synthesis_of"
      ],
      "description": "holds between two molecular entities where the action or effect of one impacts the rate of chemical synthesis of the other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/affects_synthesis_of",
      "multivalued": true,
      "inherited": true,
      "owner": "affects_synthesis_of",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "increases_synthesis_of",
      "definition_uri": "https://w3id.org/biolink/vocab/increases_synthesis_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_increases_synthesis_of"
      ],
      "description": "holds between two molecular entities where the action or effect of one increases the rate of chemical synthesis of the other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_synthesis_of",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/increases_synthesis_of",
      "multivalued": true,
      "inherited": true,
      "owner": "increases_synthesis_of",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "decreases_synthesis_of",
      "definition_uri": "https://w3id.org/biolink/vocab/decreases_synthesis_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_synthesis_of",
        "http://translator.renci.org/GAMMA_inhibition_of_synthesis"
      ],
      "description": "holds between two molecular entities where the action or effect of one decreases the rate of chemical synthesis of the other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_synthesis_of",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/decreases_synthesis_of",
      "multivalued": true,
      "inherited": true,
      "owner": "decreases_synthesis_of",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "affects_degradation_of",
      "definition_uri": "https://w3id.org/biolink/vocab/affects_degradation_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_affects_degradation_of"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/CTD_affects_cleavage",
        "http://translator.ncats.nih.gov/CTD_affects_hydrolysis"
      ],
      "description": "holds between two molecular entities where the action or effect of one impacts the rate of degradation of the other within a system of interest, where chemical degradation is defined act or process of simplifying or breaking down a molecule into smaller parts, either naturally or artificially (Oxford English Dictionary, UK, 1995)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/affects_degradation_of",
      "multivalued": true,
      "inherited": true,
      "owner": "affects_degradation_of",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "increases_degradation_of",
      "definition_uri": "https://w3id.org/biolink/vocab/increases_degradation_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_increases_degradation_of"
      ],
      "close_mappings": [
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/degrader",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/proteolytic_enzyme",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/hydrolytic_enzyme"
      ],
      "related_mappings": [
        "http://translator.renci.org/GAMMA_substrate",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/substrate"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/CTD_increases_cleavage",
        "http://translator.ncats.nih.gov/CTD_increases_hydrolysis",
        "http://purl.obolibrary.org/obo/GOREL_0002004"
      ],
      "description": "holds between two molecular entities where the action or effect of one increases the rate of degradation of the other within a system of interest",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_degradation_of",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/increases_degradation_of",
      "multivalued": true,
      "inherited": true,
      "owner": "increases_degradation_of",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "decreases_degradation_of",
      "definition_uri": "https://w3id.org/biolink/vocab/decreases_degradation_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_degradation_of"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_cleavage",
        "http://translator.ncats.nih.gov/CTD_decreases_hydrolysis"
      ],
      "description": "holds between two molecular entities where the action or effect of one decreases the rate of degradation of the other within a system of interest",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_degradation_of",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/decreases_degradation_of",
      "multivalued": true,
      "inherited": true,
      "owner": "decreases_degradation_of",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "affects_mutation_rate_of",
      "definition_uri": "https://w3id.org/biolink/vocab/affects_mutation_rate_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_affects_mutation_rate_of"
      ],
      "broad_mappings": [
        "http://translator.ncats.nih.gov/CTD_affects_mutagenesis"
      ],
      "description": "holds between a molecular entity and a genomic entity where the action or effect of the molecular entity impacts the rate of mutation of the genomic entity within a system of interest",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/affects_mutation_rate_of",
      "multivalued": true,
      "inherited": true,
      "owner": "affects_mutation_rate_of",
      "range": "GenomicEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "increases_mutation_rate_of",
      "definition_uri": "https://w3id.org/biolink/vocab/increases_mutation_rate_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_increases_mutation_rate_of"
      ],
      "broad_mappings": [
        "http://translator.ncats.nih.gov/CTD_increases_mutagenesis"
      ],
      "description": "holds between a molecular entity and a genomic entity where the action or effect of the molecular entity increases the rate of mutation of the genomic entity within a system of interest",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_mutation_rate_of",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/increases_mutation_rate_of",
      "multivalued": true,
      "inherited": true,
      "owner": "increases_mutation_rate_of",
      "range": "GenomicEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "decreases_mutation_rate_of",
      "definition_uri": "https://w3id.org/biolink/vocab/decreases_mutation_rate_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_mutation_rate_of"
      ],
      "broad_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_mutagenesis"
      ],
      "description": "holds between a molecular entity and a genomic entity where the action or effect of the molecular entity decreases the rate of mutation of the genomic entity within a system of interest",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_mutation_rate_of",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/decreases_mutation_rate_of",
      "multivalued": true,
      "inherited": true,
      "owner": "decreases_mutation_rate_of",
      "range": "GenomicEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "affects_response_to",
      "definition_uri": "https://w3id.org/biolink/vocab/affects_response_to",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_affects_response_to"
      ],
      "description": "holds between two molecular entities where the action or effect of one impacts the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) to the other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/affects_response_to",
      "multivalued": true,
      "inherited": true,
      "owner": "affects_response_to",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "increases_response_to",
      "definition_uri": "https://w3id.org/biolink/vocab/increases_response_to",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_increases_response_to"
      ],
      "description": "holds between two molecular entities where the action or effect of one increases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) to the other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_response_to",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/increases_response_to",
      "multivalued": true,
      "inherited": true,
      "owner": "increases_response_to",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "decreases_response_to",
      "definition_uri": "https://w3id.org/biolink/vocab/decreases_response_to",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_response_to"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_response_to_substance",
        "http://translator.renci.org/GAMMA_desensitize_the_target"
      ],
      "description": "holds between two molecular entities where the action or effect of one decreases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) to the other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_response_to",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/decreases_response_to",
      "multivalued": true,
      "inherited": true,
      "owner": "decreases_response_to",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "affects_splicing_of",
      "definition_uri": "https://w3id.org/biolink/vocab/affects_splicing_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_affects_RNA_splicing"
      ],
      "broad_mappings": [
        "http://translator.ncats.nih.gov/CTD_affects_splicing_of"
      ],
      "description": "holds between a molecular entity and an mRNA where the action or effect of the molecular entity impacts the splicing of the mRNA",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/affects_splicing_of",
      "multivalued": true,
      "inherited": true,
      "owner": "affects_splicing_of",
      "range": "Transcript",
      "@type": "SlotDefinition"
    },
    {
      "name": "increases_splicing_of",
      "definition_uri": "https://w3id.org/biolink/vocab/increases_splicing_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_increases_RNA_splicing"
      ],
      "broad_mappings": [
        "http://translator.ncats.nih.gov/CTD_increases_splicing_of"
      ],
      "description": "holds between a molecular entity and an mRNA where the action or effect of the molecular entity increases the proper splicing of the mRNA",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_splicing_of",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/increases_splicing_of",
      "multivalued": true,
      "inherited": true,
      "owner": "increases_splicing_of",
      "range": "Transcript",
      "@type": "SlotDefinition"
    },
    {
      "name": "decreases_splicing_of",
      "definition_uri": "https://w3id.org/biolink/vocab/decreases_splicing_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_RNA_splicing"
      ],
      "broad_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_splicing_of"
      ],
      "description": "holds between a molecular entity and an mRNA where the action or effect of the molecular entity decreases the proper splicing of the mRNA",
      "in_subset": [
        "translator_minimal"
      ],
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      "is_a": "affects_splicing_of",
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    },
    {
      "name": "entity_regulated_by_entity",
      "definition_uri": "https://w3id.org/biolink/vocab/entity_regulated_by_entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affected_by",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/entity_regulated_by_entity",
      "multivalued": true,
      "inherited": true,
      "owner": "entity_regulated_by_entity",
      "inverse": "entity_regulates_entity",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "entity_positively_regulates_entity",
      "definition_uri": "https://w3id.org/biolink/vocab/entity_positively_regulates_entity",
      "aliases": [
        "activity directly positively regulates activity of"
      ],
      "local_names": [
        {
          "local_name_source": "translator",
          "local_name_value": "positively regulates",
          "@type": "LocalName"
        },
        {
          "local_name_source": "ro",
          "local_name_value": "activity directly positively regulates activity of",
          "@type": "LocalName"
        }
      ],
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002450"
      ],
      "narrow_mappings": [
        "https://skr3.nlm.nih.gov/SemMedDBSTIMULATES",
        "https://skr3.nlm.nih.gov/SemMedDBstimulates",
        "http://translator.ncats.nih.gov/hetio_UPREGULATES_AuG",
        "http://translator.ncats.nih.gov/hetio_UPREGULATES_DuG"
      ],
      "broad_mappings": [
        "http://purl.obolibrary.org/obo/RO_0004034"
      ],
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "entity_regulates_entity",
      "mixins": [
        "positively_regulates"
      ],
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/entity_positively_regulates_entity",
      "multivalued": true,
      "inherited": true,
      "owner": "entity_positively_regulates_entity",
      "inverse": "entity_positively_regulated_by_entity",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "entity_positively_regulated_by_entity",
      "definition_uri": "https://w3id.org/biolink/vocab/entity_positively_regulated_by_entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "entity_regulated_by_entity",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/entity_positively_regulated_by_entity",
      "multivalued": true,
      "inherited": true,
      "owner": "entity_positively_regulated_by_entity",
      "inverse": "entity_positively_regulates_entity",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "entity_negatively_regulates_entity",
      "definition_uri": "https://w3id.org/biolink/vocab/entity_negatively_regulates_entity",
      "aliases": [
        "activity directly negatively regulates activity of"
      ],
      "local_names": [
        {
          "local_name_source": "translator",
          "local_name_value": "negatively regulates",
          "@type": "LocalName"
        },
        {
          "local_name_source": "ro",
          "local_name_value": "activity directly negatively regulates activity of",
          "@type": "LocalName"
        }
      ],
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002449"
      ],
      "narrow_mappings": [
        "https://skr3.nlm.nih.gov/SemMedDBINHIBITS",
        "https://skr3.nlm.nih.gov/SemMedDBinhibits",
        "http://translator.ncats.nih.gov/hetio_DOWNREGULATES_AdG",
        "http://translator.ncats.nih.gov/hetio_DOWNREGULATES_DdG"
      ],
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "entity_regulates_entity",
      "mixins": [
        "negatively_regulates"
      ],
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/entity_negatively_regulates_entity",
      "multivalued": true,
      "inherited": true,
      "owner": "entity_negatively_regulates_entity",
      "inverse": "entity_negatively_regulated_by_entity",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "entity_negatively_regulated_by_entity",
      "definition_uri": "https://w3id.org/biolink/vocab/entity_negatively_regulated_by_entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "entity_regulated_by_entity",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/entity_negatively_regulated_by_entity",
      "multivalued": true,
      "inherited": true,
      "owner": "entity_negatively_regulated_by_entity",
      "inverse": "entity_negatively_regulates_entity",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "disrupts",
      "definition_uri": "https://w3id.org/biolink/vocab/disrupts",
      "exact_mappings": [
        "https://skr3.nlm.nih.gov/SemMedDBDISRUPTS",
        "https://skr3.nlm.nih.gov/SemMedDBdisrupts",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/disrupting_agent"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/RO_0004024",
        "http://purl.obolibrary.org/obo/RO_0004025",
        "http://kg1endpoint.rtx.ai/disease_causes_disruption_of"
      ],
      "description": "describes a relationship where one entity degrades or interferes with the structure, function, or occurrence of another.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/disrupts",
      "multivalued": true,
      "inherited": true,
      "owner": "disrupts",
      "inverse": "disrupted_by",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "disrupted_by",
      "definition_uri": "https://w3id.org/biolink/vocab/disrupted_by",
      "description": "describes a relationship where the structure, function, or occurrence of one entity is degraded or interfered with by another.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affected_by",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/disrupted_by",
      "multivalued": true,
      "inherited": true,
      "owner": "disrupted_by",
      "inverse": "disrupts",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_product_of",
      "definition_uri": "https://w3id.org/biolink/vocab/gene_product_of",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002204"
      ],
      "description": "definition x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of thatf process is either y or something that is ribosomally translated from x",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "GeneProductMixin",
      "slot_uri": "https://w3id.org/biolink/vocab/gene_product_of",
      "multivalued": true,
      "inherited": true,
      "owner": "gene_product_of",
      "inverse": "has_gene_product",
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_gene_product",
      "definition_uri": "https://w3id.org/biolink/vocab/has_gene_product",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002205",
        "https://www.wikidata.org/wiki/Property:P688",
        "http://purl.obolibrary.org/obo/NCIT_gene_encodes_gene_product"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/PR_has_gene_template"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R178"
      ],
      "description": "holds between a gene and a transcribed and/or translated product generated from it",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "Gene",
      "slot_uri": "https://w3id.org/biolink/vocab/has_gene_product",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "has_gene_product",
      "inverse": "gene_product_of",
      "range": "GeneProductMixin",
      "@type": "SlotDefinition"
    },
    {
      "name": "transcribed_to",
      "definition_uri": "https://w3id.org/biolink/vocab/transcribed_to",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002511",
        "http://semanticscience.org/resource/SIO_010080"
      ],
      "description": "inverse of transcribed from",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "Gene",
      "slot_uri": "https://w3id.org/biolink/vocab/transcribed_to",
      "multivalued": true,
      "inherited": true,
      "owner": "transcribed_to",
      "inverse": "transcribed_from",
      "range": "Transcript",
      "@type": "SlotDefinition"
    },
    {
      "name": "transcribed_from",
      "definition_uri": "https://w3id.org/biolink/vocab/transcribed_from",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002510",
        "http://semanticscience.org/resource/SIO_010081"
      ],
      "description": "x is transcribed from y if and only if x is synthesized from template y",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "Transcript",
      "slot_uri": "https://w3id.org/biolink/vocab/transcribed_from",
      "multivalued": true,
      "inherited": true,
      "owner": "transcribed_from",
      "inverse": "transcribed_to",
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "translates_to",
      "definition_uri": "https://w3id.org/biolink/vocab/translates_to",
      "close_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002513",
        "http://semanticscience.org/resource/SIO_010082"
      ],
      "description": "x (amino acid chain/polypeptide) is the ribosomal translation of y (transcript) if and only if a ribosome reads y (transcript) through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces x (amino acid chain/polypeptide)",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "Transcript",
      "slot_uri": "https://w3id.org/biolink/vocab/translates_to",
      "multivalued": true,
      "inherited": true,
      "owner": "translates_to",
      "inverse": "translation_of",
      "range": "Protein",
      "@type": "SlotDefinition"
    },
    {
      "name": "translation_of",
      "definition_uri": "https://w3id.org/biolink/vocab/translation_of",
      "close_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002512",
        "http://semanticscience.org/resource/SIO_010083"
      ],
      "description": "inverse of translates to",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "Protein",
      "slot_uri": "https://w3id.org/biolink/vocab/translation_of",
      "multivalued": true,
      "inherited": true,
      "owner": "translation_of",
      "inverse": "translates_to",
      "range": "Transcript",
      "@type": "SlotDefinition"
    },
    {
      "name": "homologous_to",
      "definition_uri": "https://w3id.org/biolink/vocab/homologous_to",
      "aliases": [
        "in homology relationship with"
      ],
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_HOM0000001",
        "http://semanticscience.org/resource/SIO_010302"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/uberon/core#sexually_homologous_to"
      ],
      "description": "holds between two biological entities that have common evolutionary origin",
      "comments": [
        "typically used to describe homology relationships between genes or gene products"
      ],
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "similar_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/homologous_to",
      "multivalued": true,
      "inherited": true,
      "owner": "homologous_to",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "paralogous_to",
      "definition_uri": "https://w3id.org/biolink/vocab/paralogous_to",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_HOM0000011"
      ],
      "description": "a homology relationship that holds between entities (typically genes) that diverged after a duplication event.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "homologous_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/paralogous_to",
      "multivalued": true,
      "inherited": true,
      "owner": "paralogous_to",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "orthologous_to",
      "definition_uri": "https://w3id.org/biolink/vocab/orthologous_to",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_HOM0000017",
        "https://www.wikidata.org/wiki/Property:P684"
      ],
      "description": "a homology relationship between entities (typically genes) that diverged after a speciation event.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "homologous_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/orthologous_to",
      "multivalued": true,
      "inherited": true,
      "owner": "orthologous_to",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "xenologous_to",
      "definition_uri": "https://w3id.org/biolink/vocab/xenologous_to",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_HOM0000018"
      ],
      "description": "a homology relationship characterized by an interspecies (horizontal) transfer since the common ancestor.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "homologous_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/xenologous_to",
      "multivalued": true,
      "inherited": true,
      "owner": "xenologous_to",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "coexists_with",
      "definition_uri": "https://w3id.org/biolink/vocab/coexists_with",
      "exact_mappings": [
        "https://skr3.nlm.nih.gov/SemMedDBCOEXISTS_WITH",
        "https://skr3.nlm.nih.gov/SemMedDBcoexists_with"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/BSPO_0000096",
        "http://purl.obolibrary.org/obo/BSPO_0000097",
        "http://purl.obolibrary.org/obo/BSPO_0000098",
        "http://purl.obolibrary.org/obo/BSPO_0000099",
        "http://purl.obolibrary.org/obo/BSPO_0000100",
        "http://purl.obolibrary.org/obo/BSPO_0000102",
        "http://purl.obolibrary.org/obo/BSPO_0000104",
        "http://purl.obolibrary.org/obo/BSPO_0000110",
        "http://purl.obolibrary.org/obo/BSPO_0000113",
        "http://purl.obolibrary.org/obo/BSPO_0015001",
        "http://purl.obolibrary.org/obo/BSPO_0015002",
        "http://purl.obolibrary.org/obo/BSPO_0015003",
        "http://purl.obolibrary.org/obo/BSPO_0015005",
        "http://purl.obolibrary.org/obo/BSPO_0015006",
        "http://purl.obolibrary.org/obo/BSPO_0015007",
        "http://purl.obolibrary.org/obo/BSPO_0015008",
        "http://purl.obolibrary.org/obo/BSPO_0015009",
        "http://purl.obolibrary.org/obo/BSPO_0015012",
        "http://purl.obolibrary.org/obo/BSPO_0015014",
        "http://purl.obolibrary.org/obo/BSPO_parallel_to",
        "http://purl.obolibrary.org/obo/uberon/core#anastomoses_with",
        "http://purl.obolibrary.org/obo/uberon/core#anteriorly_connected_to",
        "http://purl.obolibrary.org/obo/uberon/core#posteriorly_connected_to",
        "http://purl.obolibrary.org/obo/uberon/core#channel_for",
        "http://purl.obolibrary.org/obo/uberon/core#channels_from",
        "http://purl.obolibrary.org/obo/uberon/core#channels_into",
        "http://purl.obolibrary.org/obo/uberon/core#conduit_for",
        "http://purl.obolibrary.org/obo/uberon/core#distally_connected_to",
        "http://purl.obolibrary.org/obo/uberon/core#extends_fibers_into",
        "http://purl.obolibrary.org/obo/uberon/core#filtered_through",
        "http://purl.obolibrary.org/obo/uberon/core#indirectly_supplies",
        "http://purl.obolibrary.org/obo/uberon/core#proximally_connected_to",
        "http://purl.obolibrary.org/obo/uberon/core#synapsed_by",
        "http://purl.obolibrary.org/obo/uberon/core#transitively_anteriorly_connected_to",
        "http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to",
        "http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to",
        "http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to",
        "http://purl.obolibrary.org/obo/ENVO_01001307",
        "http://purl.obolibrary.org/obo/FMA_adjacent_to",
        "http://purl.obolibrary.org/obo/FMA_afferent_to",
        "http://purl.obolibrary.org/obo/FMA_anterior_to",
        "http://purl.obolibrary.org/obo/FMA_anteroinferior_to",
        "http://purl.obolibrary.org/obo/FMA_anterolateral_to",
        "http://purl.obolibrary.org/obo/FMA_anteromedial_to",
        "http://purl.obolibrary.org/obo/FMA_anterosuperior_to",
        "http://purl.obolibrary.org/obo/FMA_arterial_supply_of",
        "http://purl.obolibrary.org/obo/FMA_has_arterial_supply",
        "http://purl.obolibrary.org/obo/FMA_articulates_with",
        "http://purl.obolibrary.org/obo/FMA_attaches_to",
        "http://purl.obolibrary.org/obo/FMA_bounded_by",
        "http://purl.obolibrary.org/obo/FMA_bounds",
        "http://purl.obolibrary.org/obo/FMA_branch_of",
        "http://purl.obolibrary.org/obo/FMA_connection_type_of",
        "http://purl.obolibrary.org/obo/FMA_continuation_branch_of",
        "http://purl.obolibrary.org/obo/FMA_continuous_distally_with",
        "http://purl.obolibrary.org/obo/FMA_continuous_proximally_with",
        "http://purl.obolibrary.org/obo/FMA_corresponds_to",
        "http://purl.obolibrary.org/obo/FMA_development_type_of",
        "http://purl.obolibrary.org/obo/FMA_developmental_stage_of",
        "http://purl.obolibrary.org/obo/FMA_direct_cell_shape_of",
        "http://purl.obolibrary.org/obo/FMA_direct_left_of",
        "http://purl.obolibrary.org/obo/FMA_direct_right_of",
        "http://purl.obolibrary.org/obo/FMA_distal_to",
        "http://purl.obolibrary.org/obo/FMA_drains_into",
        "http://purl.obolibrary.org/obo/FMA_efferent_to",
        "http://purl.obolibrary.org/obo/FMA_external_to",
        "http://purl.obolibrary.org/obo/FMA_formed_by",
        "http://purl.obolibrary.org/obo/FMA_forms",
        "http://purl.obolibrary.org/obo/FMA_full_grown_phenotype_of",
        "http://purl.obolibrary.org/obo/FMA_has_full_grown_phenotype",
        "http://purl.obolibrary.org/obo/FMA_fuses_with",
        "http://purl.obolibrary.org/obo/FMA_fusion_of",
        "http://purl.obolibrary.org/obo/FMA_has_fusion",
        "http://purl.obolibrary.org/obo/FMA_germ_origin_of",
        "http://purl.obolibrary.org/obo/FMA_has_germ_origin",
        "http://purl.obolibrary.org/obo/FMA_has_adherent",
        "http://purl.obolibrary.org/obo/FMA_has_branch",
        "http://purl.obolibrary.org/obo/FMA_has_connection_type",
        "http://purl.obolibrary.org/obo/FMA_has_continuation_branch",
        "http://purl.obolibrary.org/obo/FMA_has_development_type",
        "http://purl.obolibrary.org/obo/FMA_has_developmental_stage",
        "http://purl.obolibrary.org/obo/FMA_has_direct_cell_shape",
        "http://purl.obolibrary.org/obo/FMA_has_inherent_3d_shape",
        "http://purl.obolibrary.org/obo/FMA_has_insertion",
        "http://purl.obolibrary.org/obo/FMA_has_lymphatic_drainage",
        "http://purl.obolibrary.org/obo/FMA_has_nerve_supply",
        "http://purl.obolibrary.org/obo/FMA_has_observed_anatomical_entity",
        "http://purl.obolibrary.org/obo/FMA_has_origin",
        "http://purl.obolibrary.org/obo/FMA_has_primary_segmental_supply",
        "http://purl.obolibrary.org/obo/FMA_has_projection",
        "http://purl.obolibrary.org/obo/FMA_has_regional_part",
        "http://purl.obolibrary.org/obo/FMA_has_related_developmental_entity",
        "http://purl.obolibrary.org/obo/FMA_has_secondary_segmental_supply",
        "http://purl.obolibrary.org/obo/FMA_has_segmental_composition",
        "http://purl.obolibrary.org/obo/FMA_has_segmental_supply",
        "http://purl.obolibrary.org/obo/FMA_has_tributary",
        "http://purl.obolibrary.org/obo/FMA_has_venous_drainage",
        "http://purl.obolibrary.org/obo/FMA_inferior_to",
        "http://purl.obolibrary.org/obo/FMA_inferolateral_to",
        "http://purl.obolibrary.org/obo/FMA_inferomedial_to",
        "http://purl.obolibrary.org/obo/FMA_inherent_3d_shape_of",
        "http://purl.obolibrary.org/obo/FMA_insertion_of",
        "http://purl.obolibrary.org/obo/FMA_internal_to",
        "http://purl.obolibrary.org/obo/FMA_lateral_to",
        "http://purl.obolibrary.org/obo/FMA_left_lateral_to",
        "http://purl.obolibrary.org/obo/FMA_left_medial_to",
        "http://purl.obolibrary.org/obo/FMA_lymphatic_drainage_of",
        "http://purl.obolibrary.org/obo/FMA_matures_from",
        "http://purl.obolibrary.org/obo/FMA_matures_into",
        "http://purl.obolibrary.org/obo/FMA_medial_to",
        "http://purl.obolibrary.org/obo/FMA_merges_with",
        "http://purl.obolibrary.org/obo/FMA_nerve_supply_of",
        "http://purl.obolibrary.org/obo/FMA_origin_of",
        "http://purl.obolibrary.org/obo/FMA_posterior_to",
        "http://purl.obolibrary.org/obo/FMA_posteroinferior_to",
        "http://purl.obolibrary.org/obo/FMA_posterolateral_to",
        "http://purl.obolibrary.org/obo/FMA_posteromedial_to",
        "http://purl.obolibrary.org/obo/FMA_posterosuperior_to",
        "http://purl.obolibrary.org/obo/FMA_primary_segmental_supply_of",
        "http://purl.obolibrary.org/obo/FMA_projects_from",
        "http://purl.obolibrary.org/obo/FMA_projects_to",
        "http://purl.obolibrary.org/obo/FMA_proximal_to",
        "http://purl.obolibrary.org/obo/FMA_receives_attachment_from",
        "http://purl.obolibrary.org/obo/FMA_receives_drainage_from",
        "http://purl.obolibrary.org/obo/FMA_receives_input_from",
        "http://purl.obolibrary.org/obo/FMA_receives_projection",
        "http://purl.obolibrary.org/obo/FMA_related_part",
        "http://purl.obolibrary.org/obo/FMA_right_lateral_to",
        "http://purl.obolibrary.org/obo/FMA_right_medial_to",
        "http://purl.obolibrary.org/obo/FMA_secondary_segmental_supply_of",
        "http://purl.obolibrary.org/obo/FMA_segmental_composition_of",
        "http://purl.obolibrary.org/obo/FMA_segmental_supply_of",
        "http://purl.obolibrary.org/obo/FMA_sends_output_to",
        "http://purl.obolibrary.org/obo/FMA_superior_to",
        "http://purl.obolibrary.org/obo/FMA_superolateral_to",
        "http://purl.obolibrary.org/obo/FMA_superomedial_to",
        "http://purl.obolibrary.org/obo/FMA_surrounded_by",
        "http://purl.obolibrary.org/obo/FMA_surrounds",
        "http://purl.obolibrary.org/obo/FMA_tributary_of",
        "http://purl.obolibrary.org/obo/FMA_venous_drainage_of",
        "http://loinc.org/rdf/has_lateral_anatomic_location",
        "http://loinc.org/rdf/has_lateral_location_presence",
        "http://purl.obolibrary.org/obo/core#distally_connected_to",
        "http://purl.obolibrary.org/obo/core#subdivision_of",
        "http://purl.obolibrary.org/obo/RO_0002219",
        "http://purl.obolibrary.org/obo/RO_0002220",
        "http://purl.obolibrary.org/obo/RO_0002221",
        "http://purl.obolibrary.org/obo/SO_has_origin",
        "http://purl.obolibrary.org/obo/UBERON_anastomoses_with",
        "http://purl.obolibrary.org/obo/UBERON_anteriorly_connected_to",
        "http://purl.obolibrary.org/obo/UBERON_channel_for",
        "http://purl.obolibrary.org/obo/UBERON_channels_from",
        "http://purl.obolibrary.org/obo/UBERON_channels_into",
        "http://purl.obolibrary.org/obo/UBERON_conduit_for",
        "http://purl.obolibrary.org/obo/UBERON_distally_connected_to",
        "http://purl.obolibrary.org/obo/UBERON_existence_starts_and_ends_during",
        "http://purl.obolibrary.org/obo/UBERON_extends_fibers_into",
        "http://purl.obolibrary.org/obo/UBERON_filtered_through",
        "http://purl.obolibrary.org/obo/UBERON_in_central_side_of",
        "http://purl.obolibrary.org/obo/UBERON_in_innermost_side_of",
        "http://purl.obolibrary.org/obo/UBERON_in_outermost_side_of",
        "http://purl.obolibrary.org/obo/UBERON_indirectly_supplies",
        "http://purl.obolibrary.org/obo/UBERON_posteriorly_connected_to",
        "http://purl.obolibrary.org/obo/UBERON_protects",
        "http://purl.obolibrary.org/obo/UBERON_proximally_connected_to",
        "http://purl.obolibrary.org/obo/UBERON_sexually_homologous_to"
      ],
      "description": "holds between two entities that are co-located in the same aggregate object, process, or spatio-temporal region",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/coexists_with",
      "multivalued": true,
      "inherited": true,
      "owner": "coexists_with",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "in_pathway_with",
      "definition_uri": "https://w3id.org/biolink/vocab/in_pathway_with",
      "related_mappings": [
        "http://semanticscience.org/resource/SIO_010532"
      ],
      "description": "holds between two genes or gene products that are part of in the same biological pathway",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "coexists_with",
      "domain": "GeneOrGeneProduct",
      "slot_uri": "https://w3id.org/biolink/vocab/in_pathway_with",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "in_pathway_with",
      "symmetric": true,
      "range": "GeneOrGeneProduct",
      "@type": "SlotDefinition"
    },
    {
      "name": "in_complex_with",
      "definition_uri": "https://w3id.org/biolink/vocab/in_complex_with",
      "related_mappings": [
        "http://semanticscience.org/resource/SIO_010497"
      ],
      "broad_mappings": [
        "http://semanticscience.org/resource/SIO_010285"
      ],
      "description": "holds between two genes or gene products that are part of (or code for products that are part of) in the same macromolecular complex mixin",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "coexists_with",
      "domain": "GeneOrGeneProduct",
      "slot_uri": "https://w3id.org/biolink/vocab/in_complex_with",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "in_complex_with",
      "symmetric": true,
      "range": "GeneOrGeneProduct",
      "@type": "SlotDefinition"
    },
    {
      "name": "in_cell_population_with",
      "definition_uri": "https://w3id.org/biolink/vocab/in_cell_population_with",
      "description": "holds between two genes or gene products that are expressed in the same cell type or population",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "coexists_with",
      "domain": "GeneOrGeneProduct",
      "slot_uri": "https://w3id.org/biolink/vocab/in_cell_population_with",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "in_cell_population_with",
      "symmetric": true,
      "range": "GeneOrGeneProduct",
      "@type": "SlotDefinition"
    },
    {
      "name": "colocalizes_with",
      "definition_uri": "https://w3id.org/biolink/vocab/colocalizes_with",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_00002325"
      ],
      "description": "holds between two entities that are observed to be located in the same place.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "coexists_with",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/colocalizes_with",
      "multivalued": true,
      "inherited": true,
      "owner": "colocalizes_with",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "genetic_association",
      "definition_uri": "https://w3id.org/biolink/vocab/genetic_association",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P2293"
      ],
      "description": "Co-occurrence of a certain allele of a genetic marker and the phenotype of interest in the same individuals at above-chance level",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/genetic_association",
      "multivalued": true,
      "inherited": true,
      "owner": "genetic_association",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_associated_with_condition",
      "definition_uri": "https://w3id.org/biolink/vocab/gene_associated_with_condition",
      "exact_mappings": [
        "http://kg1endpoint.rtx.ai/gene_associated_with_condition"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R38",
        "http://purl.obolibrary.org/obo/NCIT_R175",
        "http://purl.obolibrary.org/obo/NCIT_R48"
      ],
      "broad_mappings": [
        "http://purl.obolibrary.org/obo/GENO_0000840",
        "http://purl.obolibrary.org/obo/GENO_0000841"
      ],
      "description": "holds between a gene and a disease or phenotypic feature that the gene or its alleles/products may influence, contribute to, or correlate with",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "genetic_association",
      "domain": "Gene",
      "slot_uri": "https://w3id.org/biolink/vocab/gene_associated_with_condition",
      "multivalued": true,
      "inherited": true,
      "owner": "gene_associated_with_condition",
      "inverse": "condition_associated_with_gene",
      "range": "DiseaseOrPhenotypicFeature",
      "@type": "SlotDefinition"
    },
    {
      "name": "condition_associated_with_gene",
      "definition_uri": "https://w3id.org/biolink/vocab/condition_associated_with_gene",
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R176",
        "http://translator.ncats.nih.gov/hetio_ASSOCIATES_DaG"
      ],
      "description": "holds between a gene and a disease or phenotypic feature that may be influenced, contribute to, or be correlated with the gene or its alleles/products",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "genetic_association",
      "domain": "DiseaseOrPhenotypicFeature",
      "slot_uri": "https://w3id.org/biolink/vocab/condition_associated_with_gene",
      "multivalued": true,
      "inherited": true,
      "owner": "condition_associated_with_gene",
      "inverse": "gene_associated_with_condition",
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "affects_risk_for",
      "definition_uri": "https://w3id.org/biolink/vocab/affects_risk_for",
      "description": "holds between two entities where exposure to one entity alters the chance of developing the other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/affects_risk_for",
      "multivalued": true,
      "inherited": true,
      "owner": "affects_risk_for",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "predisposes",
      "definition_uri": "https://w3id.org/biolink/vocab/predisposes",
      "exact_mappings": [
        "https://skr3.nlm.nih.gov/SemMedDBPREDISPOSES",
        "https://skr3.nlm.nih.gov/SemMedDBpredisposes"
      ],
      "description": "holds between two entities where exposure to one entity increases the chance of developing the other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_risk_for",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/predisposes",
      "multivalued": true,
      "inherited": true,
      "owner": "predisposes",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "contributes_to",
      "definition_uri": "https://w3id.org/biolink/vocab/contributes_to",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002326"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/IDO_0000664"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/CTD_marker_mechanism",
        "http://purl.obolibrary.org/obo/MONDO_predisposes_towards",
        "http://purl.obolibrary.org/obo/RO_0002255",
        "http://purl.obolibrary.org/obo/RO_0003304"
      ],
      "description": "holds between two entities where the occurrence, existence, or activity of one causes or contributes to the occurrence or generation of the other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/contributes_to",
      "multivalued": true,
      "inherited": true,
      "owner": "contributes_to",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "causes",
      "definition_uri": "https://w3id.org/biolink/vocab/causes",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002506",
        "https://skr3.nlm.nih.gov/SemMedDBCAUSES",
        "https://skr3.nlm.nih.gov/SemMedDBcauses",
        "https://www.wikidata.org/wiki/Property:P1542",
        "http://purl.obolibrary.org/obo/SNOMED_cause_of"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/MONDO_disease_triggers",
        "http://purl.obolibrary.org/obo/GOREL_0000040",
        "http://purl.obolibrary.org/obo/MONDO_disease_causes_feature",
        "http://purl.obolibrary.org/obo/MONDO_disease_triggers",
        "http://purl.obolibrary.org/obo/NCIT_allele_has_abnormality",
        "http://purl.obolibrary.org/obo/NCIT_biological_process_has_result_biological_process",
        "http://purl.obolibrary.org/obo/NCIT_chemical_or_drug_has_physiologic_effect",
        "http://purl.obolibrary.org/obo/NCIT_chemical_or_drug_initiates_biological_process",
        "http://purl.obolibrary.org/obo/NCIT_process_initiates_biological_process",
        "http://purl.obolibrary.org/obo/NCIT_chromosome_mapped_to_disease",
        "http://purl.obolibrary.org/obo/NCIT_disease_has_normal_tissue_origin",
        "http://purl.obolibrary.org/obo/nbo#in_response_to",
        "http://www.orpha.net/ORDO/Orphanet_317343",
        "http://www.orpha.net/ORDO/Orphanet_317344",
        "http://www.orpha.net/ORDO/Orphanet_317346",
        "http://www.orpha.net/ORDO/Orphanet_410295",
        "http://www.orpha.net/ORDO/Orphanet_410296",
        "http://purl.obolibrary.org/obo/RO_0002256",
        "http://purl.obolibrary.org/obo/RO_0002315",
        "http://purl.obolibrary.org/obo/RO_0002507",
        "http://purl.obolibrary.org/obo/RO_0002509",
        "http://purl.obolibrary.org/obo/RO_0004001",
        "http://kg1endpoint.rtx.ai/capable_of_part_of",
        "http://purl.obolibrary.org/obo/SNOMED_causative_agent_of",
        "http://purl.obolibrary.org/obo/SNOMED_has_realization",
        "http://identifiers.org/umls/has_physiologic_effect"
      ],
      "broad_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002410"
      ],
      "description": "holds between two entities where the occurrence, existence, or activity of one causes the occurrence or generation of the other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "contributes_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/causes",
      "multivalued": true,
      "inherited": true,
      "owner": "causes",
      "inverse": "caused_by",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "caused_by",
      "definition_uri": "https://w3id.org/biolink/vocab/caused_by",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P828"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/RO_0001022",
        "http://purl.obolibrary.org/obo/RO_0002608",
        "http://purl.obolibrary.org/obo/RO_0004019",
        "http://purl.obolibrary.org/obo/RO_0004020",
        "http://purl.obolibrary.org/obo/RO_0004028",
        "http://purl.obolibrary.org/obo/RO_0009501",
        "http://kg1endpoint.rtx.ai/disease_caused_by_disruption_of",
        "http://kg1endpoint.rtx.ai/disease_has_basis_in_dysfunction_of",
        "http://kg1endpoint.rtx.ai/realized_in_response_to",
        "http://kg1endpoint.rtx.ai/realized_in_response_to_stimulus"
      ],
      "description": "holds between two entities where the occurrence, existence, or activity of one is caused by the occurrence or generation of the other",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/caused_by",
      "multivalued": true,
      "inherited": true,
      "owner": "caused_by",
      "inverse": "causes",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "ameliorates",
      "definition_uri": "https://w3id.org/biolink/vocab/ameliorates",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0003307",
        "http://translator.ncats.nih.gov/CTD_therapeutic"
      ],
      "description": "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects",
      "domain": "BiologicalEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/ameliorates",
      "multivalued": true,
      "inherited": true,
      "owner": "ameliorates",
      "range": "DiseaseOrPhenotypicFeature",
      "@type": "SlotDefinition"
    },
    {
      "name": "exacerbates",
      "definition_uri": "https://w3id.org/biolink/vocab/exacerbates",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0003309"
      ],
      "description": "A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects",
      "domain": "BiologicalEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/exacerbates",
      "multivalued": true,
      "inherited": true,
      "owner": "exacerbates",
      "range": "DiseaseOrPhenotypicFeature",
      "@type": "SlotDefinition"
    },
    {
      "name": "treats",
      "definition_uri": "https://w3id.org/biolink/vocab/treats",
      "aliases": [
        "is substance that treats"
      ],
      "exact_mappings": [
        "http://identifiers.org/drugbank/treats",
        "https://skr3.nlm.nih.gov/SemMedDBTREATS",
        "https://skr3.nlm.nih.gov/SemMedDBtreats",
        "https://www.wikidata.org/wiki/Property:P2175"
      ],
      "related_mappings": [
        "http://purl.obolibrary.org/obo/MONDO_disease_responds_to"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002606",
        "http://purl.obolibrary.org/obo/NCIT_regimen_has_accepted_use_for_disease",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_approved_unknown_phase",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_0",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_1",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_1_or_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_2_or_phase_3",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_3",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_0",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_1",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_1_or_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_2_or_phase_3",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_3",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_0",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_1",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_1_or_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_2_or_phase_3",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_3",
        "http://kg1endpoint.rtx.ai/indicated_for",
        "http://purl.obolibrary.org/obo/SNOMED_plays_role"
      ],
      "broad_mappings": [
        "http://purl.obolibrary.org/obo/RO_0003307"
      ],
      "description": "holds between a therapeutic procedure or chemical substance and a disease or phenotypic feature that it is used to treat",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ameliorates",
      "domain": "ChemicalOrDrugOrTreatment",
      "slot_uri": "https://w3id.org/biolink/vocab/treats",
      "multivalued": true,
      "inherited": true,
      "owner": "treats",
      "inverse": "treated_by",
      "range": "DiseaseOrPhenotypicFeature",
      "@type": "SlotDefinition"
    },
    {
      "name": "treated_by",
      "definition_uri": "https://w3id.org/biolink/vocab/treated_by",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P2176",
        "http://purl.obolibrary.org/obo/MONDO_disease_responds_to"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002302"
      ],
      "description": "holds between a disease or phenotypic feature and a therapeutic process or chemical substance that is used to treat the condition",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "DiseaseOrPhenotypicFeature",
      "slot_uri": "https://w3id.org/biolink/vocab/treated_by",
      "multivalued": true,
      "inherited": true,
      "owner": "treated_by",
      "inverse": "treats",
      "range": "Treatment",
      "@type": "SlotDefinition"
    },
    {
      "name": "approved_to_treat",
      "definition_uri": "https://w3id.org/biolink/vocab/approved_to_treat",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_C172573"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R172",
        "http://purl.obolibrary.org/obo/NCIT_regimen_has_accepted_use_for_disease",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_approved_unknown_phase",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_0",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_1",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_1_or_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_2_or_phase_3",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_3",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_0",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_1",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_1_or_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_2_or_phase_3",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_3",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_0",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_1",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_1_or_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_2",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_2_or_phase_3",
        "http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_3"
      ],
      "description": "holds between a therapeutic procedure or chemical substance and a disease or phenotypic feature for which it is approved for treatment to some level of clinical trial. Note that in terms of REPODB narrow mappings, terms containing 'suspended', 'terminated' or 'withdrawn' should be mapped onto associations using this term for which 'negated: true' is asserted.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "treats",
      "domain": "ChemicalOrDrugOrTreatment",
      "slot_uri": "https://w3id.org/biolink/vocab/approved_to_treat",
      "multivalued": true,
      "inherited": true,
      "owner": "approved_to_treat",
      "inverse": "approved_for_treatment_by",
      "range": "DiseaseOrPhenotypicFeature",
      "@type": "SlotDefinition"
    },
    {
      "name": "approved_for_treatment_by",
      "definition_uri": "https://w3id.org/biolink/vocab/approved_for_treatment_by",
      "description": "holds between a disease or phenotypic feature and a therapeutic process or chemical substance that is approved for treatment of the condition (or not, if negated) to some level of clinical trial",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "treated_by",
      "domain": "DiseaseOrPhenotypicFeature",
      "slot_uri": "https://w3id.org/biolink/vocab/approved_for_treatment_by",
      "multivalued": true,
      "inherited": true,
      "owner": "approved_for_treatment_by",
      "inverse": "approved_to_treat",
      "range": "Treatment",
      "@type": "SlotDefinition"
    },
    {
      "name": "prevents",
      "definition_uri": "https://w3id.org/biolink/vocab/prevents",
      "exact_mappings": [
        "https://skr3.nlm.nih.gov/SemMedDBPREVENTS",
        "https://skr3.nlm.nih.gov/SemMedDBprevents"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002599"
      ],
      "description": "holds between an entity whose application or use reduces the likelihood of a potential outcome. Typically used to associate a chemical substance, exposure, activity, or medical intervention that can prevent the onset a disease or phenotypic feature.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects_risk_for",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/prevents",
      "multivalued": true,
      "inherited": true,
      "owner": "prevents",
      "inverse": "prevented_by",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "prevented_by",
      "definition_uri": "https://w3id.org/biolink/vocab/prevented_by",
      "description": "holds between a potential outcome of which the likelihood was reduced by the application or use of an entity.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/prevented_by",
      "multivalued": true,
      "inherited": true,
      "owner": "prevented_by",
      "inverse": "prevents",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "correlated_with",
      "definition_uri": "https://w3id.org/biolink/vocab/correlated_with",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002610",
        "http://purl.obolibrary.org/obo/PATO_correlates_with"
      ],
      "narrow_mappings": [
        "http://loinc.org/rdf/associated_with",
        "http://purl.obolibrary.org/obo/NCIT_is_associated_disease_of",
        "http://purl.obolibrary.org/obo/NCIT_is_cytogenetic_abnormality_of_disease",
        "http://www.orpha.net/ORDO/Orphanet_317345",
        "https://www.cancer.gov/publications/pdq#associated_disease",
        "http://purl.obolibrary.org/obo/RO_0004029",
        "http://kg1endpoint.rtx.ai/associated_with_disease",
        "http://purl.obolibrary.org/obo/SNOMED_associated_with",
        "http://purl.obolibrary.org/obo/SNOMED_has_associated_finding"
      ],
      "description": "holds between any two named thing entities. For example, correlated_with holds between a disease or phenotypic feature and a measurable molecular entity that is used as an indicator of the presence or state of the disease or feature.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/correlated_with",
      "multivalued": true,
      "inherited": true,
      "owner": "correlated_with",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "positively_correlated_with",
      "definition_uri": "https://w3id.org/biolink/vocab/positively_correlated_with",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_positive_correlation"
      ],
      "description": "holds between any two named thing entities \"correlated with\" one another in a positive manner.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "correlated_with",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/positively_correlated_with",
      "multivalued": true,
      "inherited": true,
      "owner": "positively_correlated_with",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "negatively_correlated_with",
      "definition_uri": "https://w3id.org/biolink/vocab/negatively_correlated_with",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_negative_correlation"
      ],
      "description": "holds between any two named thing entities \"correlated with\" one another in a negative manner.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "correlated_with",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/negatively_correlated_with",
      "multivalued": true,
      "inherited": true,
      "owner": "negatively_correlated_with",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "coexpressed_with",
      "definition_uri": "https://w3id.org/biolink/vocab/coexpressed_with",
      "description": "holds between any two genes or gene products, in which both are generally expressed within a single defined experimental context.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "correlated_with",
      "domain": "GeneOrGeneProduct",
      "slot_uri": "https://w3id.org/biolink/vocab/coexpressed_with",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "coexpressed_with",
      "symmetric": true,
      "range": "GeneOrGeneProduct",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_biomarker",
      "definition_uri": "https://w3id.org/biolink/vocab/has_biomarker",
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_disease_has_finding",
        "http://purl.obolibrary.org/obo/NCIT_disease_has_molecular_abnormality",
        "http://purl.obolibrary.org/obo/NCIT_disease_is_marked_by_gene"
      ],
      "description": "holds between a disease or phenotypic feature and a measurable molecular entity that is used as an indicator of the presence or state of the disease or feature.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "correlated_with",
      "domain": "DiseaseOrPhenotypicFeature",
      "slot_uri": "https://w3id.org/biolink/vocab/has_biomarker",
      "multivalued": true,
      "inherited": true,
      "owner": "has_biomarker",
      "inverse": "biomarker_for",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "biomarker_for",
      "definition_uri": "https://w3id.org/biolink/vocab/biomarker_for",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R39"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R47",
        "http://purl.obolibrary.org/obo/NCIT_genetic_biomarker_related_to",
        "http://purl.obolibrary.org/obo/NCIT_is_molecular_abnormality_of_disease",
        "http://www.orpha.net/ORDO/Orphanet_465410",
        "https://skr3.nlm.nih.gov/SemMedDBdiagnoses"
      ],
      "broad_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002607"
      ],
      "description": "holds between a measurable molecular entity and a disease or phenotypic feature, where the entity is used as an indicator of the presence or state of the disease or feature.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "correlated_with",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/biomarker_for",
      "multivalued": true,
      "inherited": true,
      "owner": "biomarker_for",
      "inverse": "has_biomarker",
      "range": "DiseaseOrPhenotypicFeature",
      "@type": "SlotDefinition"
    },
    {
      "name": "expressed_in",
      "definition_uri": "https://w3id.org/biolink/vocab/expressed_in",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002206"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R49",
        "http://purl.obolibrary.org/obo/NCIT_R46",
        "http://kg1endpoint.rtx.ai/expressed_in"
      ],
      "description": "holds between a gene or gene product and an anatomical entity in which it is expressed",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "GeneOrGeneProduct",
      "slot_uri": "https://w3id.org/biolink/vocab/expressed_in",
      "multivalued": true,
      "inherited": true,
      "owner": "expressed_in",
      "inverse": "expresses",
      "range": "AnatomicalEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "expresses",
      "definition_uri": "https://w3id.org/biolink/vocab/expresses",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002292",
        "http://translator.ncats.nih.gov/hetio_EXPRESSES_AeG"
      ],
      "description": "holds between an anatomical entity and gene or gene product that is expressed there",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "AnatomicalEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/expresses",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "expresses",
      "inverse": "expressed_in",
      "range": "GeneOrGeneProduct",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_phenotype",
      "definition_uri": "https://w3id.org/biolink/vocab/has_phenotype",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002200",
        "http://kg1endpoint.rtx.ai/has_phenotype",
        "http://purl.obolibrary.org/obo/SNOMED_characterized_by"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/OMIM_phenotype_of"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R89",
        "http://purl.obolibrary.org/obo/doid#has_symptom",
        "http://purl.obolibrary.org/obo/RO_0004022"
      ],
      "broad_mappings": [
        "http://translator.ncats.nih.gov/hetio_PRESENTS_DpS",
        "http://purl.obolibrary.org/obo/NCIT_R115",
        "http://purl.obolibrary.org/obo/OMIM_has_phenotype"
      ],
      "description": "holds between a biological entity and a phenotype, where a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature).",
      "notes": [
        "check the range"
      ],
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "BiologicalEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/has_phenotype",
      "multivalued": true,
      "inherited": true,
      "owner": "has_phenotype",
      "inverse": "phenotype_of",
      "range": "PhenotypicFeature",
      "@type": "SlotDefinition"
    },
    {
      "name": "phenotype_of",
      "definition_uri": "https://w3id.org/biolink/vocab/phenotype_of",
      "description": "holds between a phenotype and a biological entity, where a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature).",
      "notes": [
        "check the domain"
      ],
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "PhenotypicFeature",
      "slot_uri": "https://w3id.org/biolink/vocab/phenotype_of",
      "multivalued": true,
      "inherited": true,
      "owner": "phenotype_of",
      "inverse": "has_phenotype",
      "range": "BiologicalEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "occurs_in",
      "definition_uri": "https://w3id.org/biolink/vocab/occurs_in",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/BFO_0000066",
        "http://smpdb.ca/pathways/#has_location",
        "http://purl.obolibrary.org/obo/SNOMED_occurs_in"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/BFO_0000067",
        "http://purl.obolibrary.org/obo/SNOMED_has_occurrence",
        "http://purl.obolibrary.org/obo/UBERON_site_of"
      ],
      "narrow_mappings": [
        "https://skr3.nlm.nih.gov/SemMedDBOCCURS_IN",
        "https://skr3.nlm.nih.gov/SemMedDBoccurs_in",
        "https://skr3.nlm.nih.gov/SemMedDBPROCESS_OF",
        "https://skr3.nlm.nih.gov/SemMedDBprocess_of",
        "http://purl.obolibrary.org/obo/uberon/core#site_of",
        "http://loinc.org/rdf/has_imaged_location",
        "http://smpdb.ca/pathways/#in_species",
        "http://purl.obolibrary.org/obo/RO_0002231",
        "http://purl.obolibrary.org/obo/RO_0002232",
        "http://purl.obolibrary.org/obo/SNOMED_has_direct_procedure_site",
        "http://purl.obolibrary.org/obo/SNOMED_has_direct_site",
        "http://purl.obolibrary.org/obo/SNOMED_has_procedure_site"
      ],
      "description": "holds between a process and a material entity or site within which the process occurs",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/occurs_in",
      "multivalued": true,
      "inherited": true,
      "owner": "occurs_in",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "located_in",
      "definition_uri": "https://w3id.org/biolink/vocab/located_in",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0001025",
        "http://purl.obolibrary.org/obo/FMA_has_location"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/GOREL_0001004",
        "http://purl.obolibrary.org/obo/BSPO_0000107",
        "http://purl.obolibrary.org/obo/BSPO_0000108",
        "http://purl.obolibrary.org/obo/BSPO_0000120",
        "http://purl.obolibrary.org/obo/BSPO_0000121",
        "http://purl.obolibrary.org/obo/BSPO_0000122",
        "http://purl.obolibrary.org/obo/BSPO_0000123",
        "http://purl.obolibrary.org/obo/BSPO_0000124",
        "http://purl.obolibrary.org/obo/BSPO_0000125",
        "http://purl.obolibrary.org/obo/BSPO_0000126",
        "http://purl.obolibrary.org/obo/BSPO_0001100",
        "http://purl.obolibrary.org/obo/BSPO_0001101",
        "http://purl.obolibrary.org/obo/BSPO_0001107",
        "http://purl.obolibrary.org/obo/BSPO_0015101",
        "http://purl.obolibrary.org/obo/BSPO_0015102",
        "http://purl.obolibrary.org/obo/BSPO_0015202",
        "http://purl.obolibrary.org/obo/uberon/core#in_central_side_of",
        "http://purl.obolibrary.org/obo/uberon/core#in_innermost_side_of",
        "http://purl.obolibrary.org/obo/uberon/core#in_outermost_side_of",
        "http://purl.obolibrary.org/obo/NCIT_R100",
        "http://www.ebi.ac.uk/efo/EFO_0000784",
        "http://purl.obolibrary.org/obo/FMA_has_location",
        "http://identifiers.org/hmdb/at_cellular_location",
        "http://identifiers.org/hmdb/at_tissue",
        "http://identifiers.org/hmdb/in_biospecimen",
        "http://loinc.org/rdf/has_imaging_focus",
        "http://purl.obolibrary.org/obo/NCIT_R156",
        "http://purl.obolibrary.org/obo/NCIT_R155",
        "http://purl.obolibrary.org/obo/NCIT_R145",
        "http://purl.obolibrary.org/obo/NCIT_R40",
        "http://purl.obolibrary.org/obo/NCIT_is_location_of_anatomic_structure",
        "http://purl.obolibrary.org/obo/NCIT_R171",
        "http://purl.obolibrary.org/obo/NCIT_R167",
        "http://purl.obolibrary.org/obo/NCIT_R165",
        "http://purl.obolibrary.org/obo/NCIT_R169",
        "http://purl.obolibrary.org/obo/NCIT_R170",
        "http://purl.obolibrary.org/obo/NCIT_R166",
        "http://purl.obolibrary.org/obo/NCIT_R168",
        "http://purl.obolibrary.org/obo/RO_0002303",
        "http://kg1endpoint.rtx.ai/disease_has_location",
        "http://purl.obolibrary.org/obo/SNOMED_has_finding_site",
        "http://purl.obolibrary.org/obo/SNOMED_has_indirect_procedure_site",
        "http://purl.obolibrary.org/obo/SNOMED_has_inherent_location"
      ],
      "description": "holds between a material entity and a material entity or site within which it is located (but of which it is not considered a part)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/located_in",
      "multivalued": true,
      "inherited": true,
      "owner": "located_in",
      "inverse": "location_of",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "location_of",
      "definition_uri": "https://w3id.org/biolink/vocab/location_of",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0001015",
        "https://skr3.nlm.nih.gov/SemMedDBLOCATION_OF",
        "https://skr3.nlm.nih.gov/SemMedDBlocation_of",
        "https://www.wikidata.org/wiki/Property:P276",
        "http://purl.obolibrary.org/obo/FMA_location_of",
        "http://kg1endpoint.rtx.ai/site_of"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/SNOMED_inherent_location_of"
      ],
      "description": "holds between material entity or site and a material entity that is located within it (but not considered a part of it)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/location_of",
      "multivalued": true,
      "inherited": true,
      "owner": "location_of",
      "inverse": "located_in",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "similar_to",
      "definition_uri": "https://w3id.org/biolink/vocab/similar_to",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_HOM0000000",
        "http://purl.obolibrary.org/obo/SO_similar_to"
      ],
      "description": "holds between an entity and some other entity with similar features.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/similar_to",
      "multivalued": true,
      "inherited": true,
      "owner": "similar_to",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "chemically_similar_to",
      "definition_uri": "https://w3id.org/biolink/vocab/chemically_similar_to",
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/CHEBI_has_parent_hydride",
        "http://purl.obolibrary.org/obo/CHEBI_has_functional_parent",
        "http://purl.obolibrary.org/obo/CHEBI_is_conjugate_acid_of",
        "http://purl.obolibrary.org/obo/CHEBI_is_conjugate_base_of",
        "http://purl.obolibrary.org/obo/CHEBI_is_enantiomer_of",
        "http://purl.obolibrary.org/obo/CHEBI_is_tautomer_of",
        "http://purl.obolibrary.org/obo/NCIT_has_salt_form"
      ],
      "description": "holds between one chemical substances and another that it approximates for purposes of scientific study, in virtue of its exhibiting similar features of the studied entity.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "similar_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/chemically_similar_to",
      "multivalued": true,
      "inherited": true,
      "owner": "chemically_similar_to",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_sequence_location",
      "definition_uri": "https://w3id.org/biolink/vocab/has_sequence_location",
      "exact_mappings": [
        "http://biohackathon.org/resource/faldo#location"
      ],
      "description": "holds between two genomic entities when the subject can be localized in sequence coordinates on the object. For example, between an exon and a chromosome/contig.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "GenomicEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/has_sequence_location",
      "multivalued": true,
      "inherited": true,
      "owner": "has_sequence_location",
      "range": "GenomicEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "model_of",
      "definition_uri": "https://w3id.org/biolink/vocab/model_of",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0003301"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/FOODON_00001301"
      ],
      "description": "holds between a thing and some other thing it approximates for purposes of scientific study, in virtue of its exhibiting similar features of the studied entity.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "similar_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/model_of",
      "multivalued": true,
      "inherited": true,
      "owner": "model_of",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "overlaps",
      "definition_uri": "https://w3id.org/biolink/vocab/overlaps",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002131"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/BSPO_0005001",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/overlaps_with",
        "http://purl.obolibrary.org/obo/RO_0002100",
        "http://purl.obolibrary.org/obo/RO_0002102",
        "http://purl.obolibrary.org/obo/RO_0002433"
      ],
      "description": "holds between entities that overlap in their extents (materials or processes)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/overlaps",
      "multivalued": true,
      "inherited": true,
      "owner": "overlaps",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_part",
      "definition_uri": "https://w3id.org/biolink/vocab/has_part",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/BFO_0000051",
        "http://purl.obolibrary.org/obo/BFO_0000055",
        "https://www.wikidata.org/wiki/Property:P527",
        "http://purl.obolibrary.org/obo/RO_0001019",
        "http://kg1endpoint.rtx.ai/has_part",
        "http://purl.bioontology.org/ontology/RXNORM/consists_of",
        "http://purl.bioontology.org/ontology/RXNORM/has_part"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/BFO_0000117",
        "http://purl.obolibrary.org/obo/FMA_has_constitutional_part",
        "http://purl.obolibrary.org/obo/FMA_has_part",
        "http://purl.obolibrary.org/obo/FMA_has_member",
        "http://purl.obolibrary.org/obo/FOODON_00001563",
        "http://purl.obolibrary.org/obo/FOODON_00002420",
        "http://loinc.org/rdf/has_component",
        "http://loinc.org/rdf/has_member",
        "http://identifiers.org/meddra/has_member",
        "http://purl.obolibrary.org/obo/MONDO_disease_has_major_feature",
        "http://purl.obolibrary.org/obo/NCIT_complex_has_physical_part",
        "http://purl.bioontology.org/ontology/NDDF/has_ingredient",
        "http://smpdb.ca/pathways/#has_element_in_bound",
        "http://purl.obolibrary.org/obo/NCIT_R50",
        "https://www.cancer.gov/publications/pdq#has_component",
        "http://smpdb.ca/pathways/#has_protein_in_complex",
        "http://purl.obolibrary.org/obo/RO_0002104",
        "http://purl.obolibrary.org/obo/RO_0002180",
        "http://purl.obolibrary.org/obo/RO_0002351",
        "http://purl.obolibrary.org/obo/RO_0002473",
        "http://purl.obolibrary.org/obo/RO_0002524",
        "http://purl.obolibrary.org/obo/RO_0002551",
        "http://kg1endpoint.rtx.ai/composed_primarily_of",
        "http://kg1endpoint.rtx.ai/contains_process",
        "http://kg1endpoint.rtx.ai/has_plasma_membrane_part",
        "http://purl.bioontology.org/ontology/RXNORM/has_ingredient",
        "http://purl.obolibrary.org/obo/SNOMED_has_component",
        "http://identifiers.org/umls/has_component"
      ],
      "broad_mappings": [
        "http://purl.obolibrary.org/obo/RO_0001019",
        "http://purl.obolibrary.org/obo/FMA_contains",
        "http://purl.bioontology.org/ontology/RXNORM/contains"
      ],
      "description": "holds between wholes and their parts (material entities or processes)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "overlaps",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_part",
      "multivalued": true,
      "inherited": true,
      "owner": "has_part",
      "inverse": "part_of",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "part_of",
      "definition_uri": "https://w3id.org/biolink/vocab/part_of",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/BFO_0000050",
        "https://skr3.nlm.nih.gov/SemMedDBPART_OF",
        "https://skr3.nlm.nih.gov/SemMedDBpart_of",
        "https://www.wikidata.org/wiki/Property:P361",
        "http://purl.obolibrary.org/obo/FMA_part_of",
        "http://purl.bioontology.org/ontology/RXNORM/constitutes",
        "http://purl.bioontology.org/ontology/RXNORM/part_of"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/BSPO_0001106",
        "http://purl.obolibrary.org/obo/BSPO_0001108",
        "http://purl.obolibrary.org/obo/BSPO_0001113",
        "http://purl.obolibrary.org/obo/BSPO_0001115",
        "http://purl.obolibrary.org/obo/uberon/core#layer_part_of",
        "http://purl.obolibrary.org/obo/uberon/core#subdivision_of",
        "http://purl.obolibrary.org/obo/uberon/core#trunk_part_of",
        "http://purl.obolibrary.org/obo/CHEBI_is_substituent_group_from",
        "https://www.ama-assn.org/practice-management/cpt/panel_element_of",
        "https://www.ama-assn.org/practice-management/cpt/panel_element_of_possibly_included",
        "http://identifiers.org/drugbank/component_of",
        "http://purl.obolibrary.org/obo/FMA_constitutional_part_of",
        "http://purl.obolibrary.org/obo/FMA_member_of",
        "http://purl.obolibrary.org/obo/FMA_regional_part_of",
        "http://purl.obolibrary.org/obo/FMA_related_developmental_entity_of",
        "http://loinc.org/rdf/component_of",
        "http://loinc.org/rdf/has_supersystem",
        "http://loinc.org/rdf/member_of",
        "http://loinc.org/rdf/multipart_of",
        "http://identifiers.org/meddra/member_of",
        "http://purl.obolibrary.org/obo/MONDO_part_of_progression_of_disease",
        "http://purl.obolibrary.org/obo/NCIT_R82",
        "http://purl.obolibrary.org/obo/NCIT_R27",
        "http://purl.obolibrary.org/obo/NCIT_is_component_of_chemotherapy_regimen",
        "http://purl.bioontology.org/ontology/NDDF/ingredient_of",
        "https://www.cancer.gov/publications/pdq#component_of",
        "http://purl.obolibrary.org/obo/RO_0002007",
        "http://purl.obolibrary.org/obo/RO_0002350",
        "http://purl.obolibrary.org/obo/RO_0002376",
        "http://purl.obolibrary.org/obo/RO_0002380",
        "http://purl.obolibrary.org/obo/RO_0002571",
        "http://purl.obolibrary.org/obo/RO_0002572",
        "http://purl.obolibrary.org/obo/RO_0002576",
        "http://purl.bioontology.org/ontology/RXNORM/ingredient_of",
        "http://purl.bioontology.org/ontology/RXNORM/ingredients_of",
        "http://purl.bioontology.org/ontology/RXNORM/precise_ingredient_of",
        "http://purl.obolibrary.org/obo/SNOMED_active_ingredient_of",
        "http://purl.obolibrary.org/obo/SNOMED_basis_of_strength_substance_of",
        "http://purl.obolibrary.org/obo/SNOMED_component_of",
        "http://purl.obolibrary.org/obo/SNOMED_direct_substance_of",
        "http://purl.obolibrary.org/obo/SNOMED_during",
        "http://purl.obolibrary.org/obo/SNOMED_focus_of",
        "http://purl.obolibrary.org/obo/SNOMED_has_dependent",
        "http://purl.obolibrary.org/obo/SNOMED_part_anatomy_structure_of",
        "http://purl.obolibrary.org/obo/SNOMED_precise_active_ingredient_of",
        "http://purl.obolibrary.org/obo/UBERON_subdivision_of",
        "http://identifiers.org/umls/component_of",
        "http://identifiers.org/umls/has_owning_affiliate",
        "http://identifiers.org/umls/owning_subsection_of",
        "https://www.nlm.nih.gov/research/umls/sourcereleasedocs/current/VANDF/ingredient_of"
      ],
      "broad_mappings": [
        "http://purl.obolibrary.org/obo/RO_0001018",
        "http://purl.obolibrary.org/obo/FMA_contained_in",
        "http://purl.bioontology.org/ontology/RXNORM/contained_in"
      ],
      "description": "holds between parts and wholes (material entities or processes)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "overlaps",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/part_of",
      "multivalued": true,
      "inherited": true,
      "owner": "part_of",
      "inverse": "has_part",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_input",
      "definition_uri": "https://w3id.org/biolink/vocab/has_input",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002233",
        "https://skr3.nlm.nih.gov/SemMedDBUSES",
        "https://skr3.nlm.nih.gov/SemMedDBuses"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002352"
      ],
      "narrow_mappings": [
        "http://loinc.org/rdf/has_fragments_for_synonyms",
        "http://loinc.org/rdf/has_system",
        "http://smpdb.ca/pathways/#has_left_element",
        "http://purl.obolibrary.org/obo/RO_0002590",
        "http://purl.obolibrary.org/obo/RO_0004009",
        "http://purl.obolibrary.org/obo/SNOMED_has_finding_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_precondition",
        "http://purl.obolibrary.org/obo/SNOMED_has_specimen_source_identity",
        "http://purl.obolibrary.org/obo/SNOMED_has_specimen_substance",
        "http://purl.obolibrary.org/obo/SNOMED_uses_access_device",
        "http://purl.obolibrary.org/obo/SNOMED_uses_device",
        "http://purl.obolibrary.org/obo/SNOMED_uses_energy",
        "http://purl.obolibrary.org/obo/SNOMED_uses_substance"
      ],
      "description": "holds between a process and a continuant, where the continuant is an input into the process",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_participant",
      "domain": "Occurrent",
      "slot_uri": "https://w3id.org/biolink/vocab/has_input",
      "multivalued": true,
      "inherited": true,
      "owner": "has_input",
      "domain_of": [
        "BiologicalProcessOrActivity"
      ],
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_output",
      "definition_uri": "https://w3id.org/biolink/vocab/has_output",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002234"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002353",
        "http://purl.obolibrary.org/obo/RO_0002354",
        "http://kg1endpoint.rtx.ai/output_of"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R31",
        "http://purl.obolibrary.org/obo/OBI_0000299",
        "http://smpdb.ca/pathways/#has_right_element",
        "http://purl.obolibrary.org/obo/RO_0002296",
        "http://purl.obolibrary.org/obo/RO_0002297",
        "http://purl.obolibrary.org/obo/RO_0002298",
        "http://purl.obolibrary.org/obo/RO_0002299",
        "http://purl.obolibrary.org/obo/RO_0002588",
        "http://purl.obolibrary.org/obo/RO_0004008"
      ],
      "description": "holds between a process and a continuant, where the continuant is an output of the process",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_participant",
      "domain": "Occurrent",
      "slot_uri": "https://w3id.org/biolink/vocab/has_output",
      "multivalued": true,
      "inherited": true,
      "owner": "has_output",
      "domain_of": [
        "BiologicalProcessOrActivity"
      ],
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_participant",
      "definition_uri": "https://w3id.org/biolink/vocab/has_participant",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0000057",
        "http://purl.obolibrary.org/obo/RO_has_participant"
      ],
      "close_mappings": [
        "https://www.wikidata.org/wiki/Property:P2283"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/BFO_0000167",
        "http://loinc.org/rdf/has_subject",
        "http://purl.obolibrary.org/obo/NCIT_pathway_has_gene_element",
        "http://purl.obolibrary.org/obo/NCIT_process_involves_gene",
        "http://purl.obolibrary.org/obo/nbo#has_participant",
        "http://smpdb.ca/pathways/#has_bound",
        "http://smpdb.ca/pathways/#has_compound",
        "http://smpdb.ca/pathways/#has_element_collection",
        "http://smpdb.ca/pathways/#has_enzyme",
        "http://purl.obolibrary.org/obo/NCIT_process_includes_biological_process",
        "http://purl.obolibrary.org/obo/OBI_0000293",
        "http://smpdb.ca/pathways/#has_nucleic_acid",
        "http://smpdb.ca/pathways/#has_protein",
        "http://smpdb.ca/pathways/#has_reaction",
        "http://purl.obolibrary.org/obo/RO_0004007",
        "http://purl.obolibrary.org/obo/RO_0004020",
        "http://purl.obolibrary.org/obo/RO_0004021",
        "http://purl.obolibrary.org/obo/SNOMED_has_indirect_device",
        "http://purl.obolibrary.org/obo/SNOMED_has_procedure_device",
        "http://purl.obolibrary.org/obo/SNOMED_has_recipient_category"
      ],
      "description": "holds between a process and a continuant, where the continuant is somehow involved in the process",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "Occurrent",
      "slot_uri": "https://w3id.org/biolink/vocab/has_participant",
      "multivalued": true,
      "inherited": true,
      "owner": "has_participant",
      "inverse": "participates_in",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "participates_in",
      "definition_uri": "https://w3id.org/biolink/vocab/participates_in",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0000056",
        "http://purl.obolibrary.org/obo/BFO_0000056",
        "http://kg1endpoint.rtx.ai/participates_in"
      ],
      "narrow_mappings": [
        "http://identifiers.org/drugbank/pathway",
        "http://identifiers.org/hmdb/in_pathway",
        "http://loinc.org/rdf/is_given_pharmaceutical_substance_for",
        "http://purl.obolibrary.org/obo/NCIT_R130",
        "http://purl.obolibrary.org/obo/NCIT_R37",
        "http://purl.obolibrary.org/obo/NCIT_R131",
        "http://purl.obolibrary.org/obo/NCIT_R51",
        "http://purl.obolibrary.org/obo/NCIT_R53",
        "http://purl.obolibrary.org/obo/OBI_0000295",
        "http://purl.obolibrary.org/obo/RO_0002216",
        "http://purl.obolibrary.org/obo/RO_0002505",
        "http://purl.obolibrary.org/obo/RO_0002565",
        "http://purl.obolibrary.org/obo/SNOMED_has_direct_device"
      ],
      "description": "holds between a continuant and a process, where the continuant is somehow involved in the process",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/participates_in",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "participates_in",
      "inverse": "has_participant",
      "range": "Occurrent",
      "@type": "SlotDefinition"
    },
    {
      "name": "actively_involved_in",
      "definition_uri": "https://w3id.org/biolink/vocab/actively_involved_in",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002331",
        "http://purl.obolibrary.org/obo/RO_0002432"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_biological_process_involves_chemical_or_drug"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_gene_involved_in_molecular_abnormality",
        "http://purl.obolibrary.org/obo/nbo#by_means",
        "http://www.orpha.net/ORDO/Orphanet_317348",
        "http://www.orpha.net/ORDO/Orphanet_317349",
        "http://www.orpha.net/ORDO/Orphanet_327767",
        "http://purl.obolibrary.org/obo/RO_0002503"
      ],
      "broad_mappings": [
        "http://kg1endpoint.rtx.ai/involved_in"
      ],
      "description": "holds between a continuant and a process or function, where the continuant actively contributes to part or all of the process or function it realizes",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "participates_in",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/actively_involved_in",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "actively_involved_in",
      "range": "Occurrent",
      "@type": "SlotDefinition"
    },
    {
      "name": "capable_of",
      "definition_uri": "https://w3id.org/biolink/vocab/capable_of",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002215",
        "http://kg1endpoint.rtx.ai/capable_of"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R52",
        "http://purl.obolibrary.org/obo/RO_0002500"
      ],
      "description": "holds between a physical entity and process or function, where the continuant alone has the ability to carry out the process or function.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "actively_involved_in",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/capable_of",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "capable_of",
      "range": "Occurrent",
      "@type": "SlotDefinition"
    },
    {
      "name": "enables",
      "definition_uri": "https://w3id.org/biolink/vocab/enables",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002327"
      ],
      "description": "holds between a physical entity and a process, where the physical entity executes the process",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "participates_in",
      "domain": "PhysicalEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/enables",
      "multivalued": true,
      "inherited": true,
      "owner": "enables",
      "inverse": "enabled_by",
      "range": "BiologicalProcessOrActivity",
      "@type": "SlotDefinition"
    },
    {
      "name": "enabled_by",
      "definition_uri": "https://w3id.org/biolink/vocab/enabled_by",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002333"
      ],
      "description": "holds between a process and a physical entity, where the physical entity executes the process",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_participant",
      "domain": "BiologicalProcessOrActivity",
      "slot_uri": "https://w3id.org/biolink/vocab/enabled_by",
      "multivalued": true,
      "inherited": true,
      "owner": "BiologicalProcessOrActivity",
      "domain_of": [
        "BiologicalProcessOrActivity"
      ],
      "inverse": "enables",
      "range": "PhysicalEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "derives_into",
      "definition_uri": "https://w3id.org/biolink/vocab/derives_into",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0001001",
        "https://skr3.nlm.nih.gov/SemMedDBCONVERTS_TO",
        "https://skr3.nlm.nih.gov/SemMedDBconverts_to",
        "http://purl.obolibrary.org/obo/FMA_derives",
        "http://purl.obolibrary.org/obo/NCIT_is_normal_cell_origin_of_disease",
        "http://purl.obolibrary.org/obo/NCIT_may_be_normal_cell_origin_of_disease"
      ],
      "description": "holds between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/derives_into",
      "multivalued": true,
      "inherited": true,
      "owner": "derives_into",
      "inverse": "derives_from",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "derives_from",
      "definition_uri": "https://w3id.org/biolink/vocab/derives_from",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0001000",
        "http://purl.obolibrary.org/obo/FMA_derives_from",
        "http://purl.obolibrary.org/obo/doid#derives_from"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/CHEBI_has_functional_parent",
        "http://purl.obolibrary.org/obo/SNOMED_has_specimen_source_topography"
      ],
      "description": "holds between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity",
      "in_subset": [
        "translator_minimal",
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/derives_from",
      "multivalued": true,
      "inherited": true,
      "owner": "derives_from",
      "inverse": "derives_into",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_metabolite_of",
      "definition_uri": "https://w3id.org/biolink/vocab/is_metabolite_of",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/CHEBI_25212"
      ],
      "description": "holds between two chemical substances in which the first one is derived from the second one as a product of metabolism",
      "comments": [
        "The CHEBI ID represents a role rather than a predicate"
      ],
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "derives_from",
      "domain": "ChemicalSubstance",
      "slot_uri": "https://w3id.org/biolink/vocab/is_metabolite_of",
      "multivalued": true,
      "inherited": true,
      "owner": "is_metabolite_of",
      "inverse": "has_metabolite",
      "range": "ChemicalSubstance",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_metabolite",
      "definition_uri": "https://w3id.org/biolink/vocab/has_metabolite",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/CHEBI_25212"
      ],
      "description": "holds between two chemical substances in which the second one is derived from the first one as a product of metabolism",
      "comments": [
        "The CHEBI ID represents a role rather than a predicate"
      ],
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "derives_into",
      "domain": "ChemicalSubstance",
      "slot_uri": "https://w3id.org/biolink/vocab/has_metabolite",
      "multivalued": true,
      "inherited": true,
      "owner": "has_metabolite",
      "inverse": "is_metabolite_of",
      "range": "ChemicalSubstance",
      "@type": "SlotDefinition"
    },
    {
      "name": "food_component_of",
      "definition_uri": "https://w3id.org/biolink/vocab/food_component_of",
      "description": "holds between a one or more chemical substances present in food, irrespective of nutritional value (i.e. could also be a contaminant or additive)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "part_of",
      "domain": "ChemicalSubstance",
      "slot_uri": "https://w3id.org/biolink/vocab/food_component_of",
      "multivalued": true,
      "inherited": true,
      "owner": "food_component_of",
      "inverse": "has_food_component",
      "range": "ChemicalSubstance",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_food_component",
      "definition_uri": "https://w3id.org/biolink/vocab/has_food_component",
      "description": "holds between food and one or more chemical substances composing it, irrespective of nutritional value (i.e. could also be a contaminant or additive)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_part",
      "domain": "ChemicalSubstance",
      "slot_uri": "https://w3id.org/biolink/vocab/has_food_component",
      "multivalued": true,
      "inherited": true,
      "owner": "has_food_component",
      "inverse": "food_component_of",
      "range": "ChemicalSubstance",
      "@type": "SlotDefinition"
    },
    {
      "name": "nutrient_of",
      "definition_uri": "https://w3id.org/biolink/vocab/nutrient_of",
      "description": "holds between a one or more chemical substances present in food, irrespective of nutritional value (i.e. could also be a contaminant or additive)",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "food_component_of",
      "domain": "ChemicalSubstance",
      "slot_uri": "https://w3id.org/biolink/vocab/nutrient_of",
      "multivalued": true,
      "inherited": true,
      "owner": "nutrient_of",
      "inverse": "has_nutrient",
      "range": "ChemicalSubstance",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_nutrient",
      "definition_uri": "https://w3id.org/biolink/vocab/has_nutrient",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Q181394"
      ],
      "description": "one or more nutrients which are growth factors for a living organism",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_food_component",
      "domain": "ChemicalSubstance",
      "slot_uri": "https://w3id.org/biolink/vocab/has_nutrient",
      "multivalued": true,
      "inherited": true,
      "owner": "has_nutrient",
      "inverse": "nutrient_of",
      "range": "ChemicalSubstance",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_active_ingredient_of",
      "definition_uri": "https://w3id.org/biolink/vocab/is_active_ingredient_of",
      "mappings": [
        "http://purl.obolibrary.org/obo/RO_0002249"
      ],
      "description": "holds between a chemical substance and a drug, in which the former is a part of the latter, and is a biologically active component",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "part_of",
      "domain": "ChemicalSubstance",
      "slot_uri": "https://w3id.org/biolink/vocab/is_active_ingredient_of",
      "multivalued": true,
      "inherited": true,
      "owner": "is_active_ingredient_of",
      "inverse": "has_active_ingredient",
      "range": "Drug",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_active_ingredient",
      "definition_uri": "https://w3id.org/biolink/vocab/has_active_ingredient",
      "mappings": [
        "http://purl.obolibrary.org/obo/RO_0002248"
      ],
      "description": "holds between a drug and a chemical substance in which the latter is a part of the former, and is a biologically active component",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_part",
      "domain": "Drug",
      "slot_uri": "https://w3id.org/biolink/vocab/has_active_ingredient",
      "multivalued": true,
      "inherited": true,
      "owner": "has_active_ingredient",
      "inverse": "is_active_ingredient_of",
      "range": "ChemicalSubstance",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_excipient_of",
      "definition_uri": "https://w3id.org/biolink/vocab/is_excipient_of",
      "mappings": [
        "https://www.wikidata.org/wiki/Q902638"
      ],
      "description": "holds between a chemical substance and a drug in which the former is a part of the latter, and is a biologically inactive component",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "part_of",
      "domain": "ChemicalSubstance",
      "slot_uri": "https://w3id.org/biolink/vocab/is_excipient_of",
      "multivalued": true,
      "inherited": true,
      "owner": "is_excipient_of",
      "inverse": "has_excipient",
      "range": "Drug",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_excipient",
      "definition_uri": "https://w3id.org/biolink/vocab/has_excipient",
      "mappings": [
        "https://www.wikidata.org/wiki/Q902638"
      ],
      "description": "holds between a drug and a chemical substances in which the latter is a part of the former, and is a biologically inactive component",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_part",
      "domain": "Drug",
      "slot_uri": "https://w3id.org/biolink/vocab/has_excipient",
      "multivalued": true,
      "inherited": true,
      "owner": "has_excipient",
      "inverse": "is_excipient_of",
      "range": "ChemicalSubstance",
      "@type": "SlotDefinition"
    },
    {
      "name": "manifestation_of",
      "definition_uri": "https://w3id.org/biolink/vocab/manifestation_of",
      "exact_mappings": [
        "https://skr3.nlm.nih.gov/SemMedDBMANIFESTATION_OF",
        "https://skr3.nlm.nih.gov/SemMedDBmanifestation_of",
        "http://purl.obolibrary.org/obo/OMIM_manifestation_of"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/SNOMED_has_definitional_manifestation"
      ],
      "broad_mappings": [
        "https://www.wikidata.org/wiki/Property:P1557"
      ],
      "description": "that part of a phenomenon which is directly observable or visibly expressed, or which gives evidence to the underlying process; used in SemMedDB for linking things like dysfunctions and processes to some disease or syndrome",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/manifestation_of",
      "multivalued": true,
      "inherited": true,
      "owner": "manifestation_of",
      "range": "Disease",
      "@type": "SlotDefinition"
    },
    {
      "name": "produces",
      "definition_uri": "https://w3id.org/biolink/vocab/produces",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0003000",
        "https://www.wikidata.org/wiki/Property:P1056",
        "https://skr3.nlm.nih.gov/SemMedDBPRODUCES",
        "https://skr3.nlm.nih.gov/SemMedDBproduces"
      ],
      "related_mappings": [
        "http://purl.obolibrary.org/obo/GOREL_0001010"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R29",
        "http://purl.obolibrary.org/obo/SNOMED_has_process_output",
        "http://purl.obolibrary.org/obo/SNOMED_specimen_procedure_of"
      ],
      "description": "holds between a material entity and a product that is generated through the intentional actions or functioning of the material entity",
      "in_subset": [
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      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/produces",
      "multivalued": true,
      "inherited": true,
      "owner": "produces",
      "inverse": "produced_by",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "produced_by",
      "definition_uri": "https://w3id.org/biolink/vocab/produced_by",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0003001"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/produced_by",
      "multivalued": true,
      "inherited": true,
      "owner": "produced_by",
      "inverse": "produces",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "temporally_related_to",
      "definition_uri": "https://w3id.org/biolink/vocab/temporally_related_to",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/SNOMED_temporally_related_to"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002082",
        "http://purl.obolibrary.org/obo/RO_0002083",
        "http://purl.obolibrary.org/obo/RO_0002092",
        "http://purl.obolibrary.org/obo/RO_0002093",
        "http://purl.obolibrary.org/obo/RO_0002223",
        "http://purl.obolibrary.org/obo/RO_0002224",
        "http://purl.obolibrary.org/obo/RO_0002229",
        "http://purl.obolibrary.org/obo/RO_0002230",
        "http://purl.obolibrary.org/obo/RO_0002488",
        "http://purl.obolibrary.org/obo/RO_0002489",
        "http://purl.obolibrary.org/obo/RO_0002492",
        "http://purl.obolibrary.org/obo/RO_0002493",
        "http://purl.obolibrary.org/obo/RO_0002496",
        "http://purl.obolibrary.org/obo/RO_0002497"
      ],
      "description": "holds between two entities with a temporal relationship",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "Occurrent",
      "slot_uri": "https://w3id.org/biolink/vocab/temporally_related_to",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "temporally_related_to",
      "symmetric": true,
      "range": "Occurrent",
      "@type": "SlotDefinition"
    },
    {
      "name": "precedes",
      "definition_uri": "https://w3id.org/biolink/vocab/precedes",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/BFO_0000063",
        "https://skr3.nlm.nih.gov/SemMedDBPRECEDES",
        "https://skr3.nlm.nih.gov/SemMedDBprecedes",
        "http://purl.obolibrary.org/obo/SNOMED_occurs_before"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002263",
        "http://purl.obolibrary.org/obo/RO_0002264"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/FMA_transforms_into",
        "http://purl.obolibrary.org/obo/RO_0002090",
        "http://purl.obolibrary.org/obo/RO_0002411",
        "http://purl.obolibrary.org/obo/RO_0002412"
      ],
      "broad_mappings": [
        "https://www.wikidata.org/wiki/Property:P156"
      ],
      "description": "holds between two processes, where one completes before the other begins",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "temporally_related_to",
      "domain": "Occurrent",
      "slot_uri": "https://w3id.org/biolink/vocab/precedes",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "precedes",
      "inverse": "preceded_by",
      "range": "Occurrent",
      "@type": "SlotDefinition"
    },
    {
      "name": "preceded_by",
      "definition_uri": "https://w3id.org/biolink/vocab/preceded_by",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/BFO_0000062"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/FMA_transforms_from",
        "http://purl.obolibrary.org/obo/RO_0002087",
        "http://purl.obolibrary.org/obo/RO_0002285"
      ],
      "broad_mappings": [
        "http://purl.obolibrary.org/obo/GENEPIO_0001739"
      ],
      "description": "holds between two processes, where the other is completed before the one begins",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "temporally_related_to",
      "domain": "Occurrent",
      "slot_uri": "https://w3id.org/biolink/vocab/preceded_by",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "preceded_by",
      "inverse": "precedes",
      "range": "Occurrent",
      "@type": "SlotDefinition"
    },
    {
      "name": "directly_interacts_with",
      "definition_uri": "https://w3id.org/biolink/vocab/directly_interacts_with",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/chembio_interacts",
        "http://translator.ncats.nih.gov/CTD_interacts_with",
        "http://translator.renci.org/GAMMA_interacts_with"
      ],
      "related_mappings": [
        "http://translator.renci.org/GAMMA_kd",
        "http://translator.renci.org/GAMMA_kb",
        "http://translator.renci.org/GAMMA_potency"
      ],
      "narrow_mappings": [
        "http://pharos.nih.govdrug_targets",
        "http://identifiers.org/drugbank/chelator",
        "http://translator.renci.org/GAMMA_antibody_binding",
        "http://translator.renci.org/GAMMA_pharmacological_chaperone",
        "http://translator.renci.org/GAMMA_releasing_agent",
        "http://translator.renci.org/GAMMA_pharmacological_chaperone",
        "http://translator.renci.org/GAMMA_releasing_agent",
        "http://translator.renci.org/GAMMA_binder",
        "http://translator.renci.org/GAMMA_binding",
        "http://translator.renci.org/GAMMA_ligand",
        "http://translator.renci.org/GAMMA_cofactor",
        "http://translator.renci.org/GAMMA_multitarget",
        "http://translator.renci.org/GAMMA_chaperone",
        "http://translator.renci.org/GAMMA_component",
        "http://translator.renci.org/GAMMA_adduct",
        "http://translator.renci.org/GAMMA_antibody",
        "http://translator.ncats.nih.gov/CTD_affects_binding",
        "https://www.dgidb.org/interaction_typesbinder",
        "https://www.dgidb.org/interaction_typescofactor"
      ],
      "broad_mappings": [
        "http://semanticscience.org/resource/SIO_000203"
      ],
      "description": "Holds between molecular entities that physically and directly interact with each other",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "interacts_with",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/directly_interacts_with",
      "multivalued": true,
      "inherited": true,
      "owner": "directly_interacts_with",
      "symmetric": true,
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "affects_expression_in",
      "definition_uri": "https://w3id.org/biolink/vocab/affects_expression_in",
      "exact_mappings": [
        "https://www.gtexportal.org/home/gene/affects_expression_in"
      ],
      "description": "Holds between a variant and an anatomical entity where the expression of the variant is located in.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "affects",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/affects_expression_in",
      "multivalued": true,
      "inherited": true,
      "owner": "affects_expression_in",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_variant_part",
      "definition_uri": "https://w3id.org/biolink/vocab/has_variant_part",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/GENO_0000382"
      ],
      "description": "holds between a genomic entity and a genotypic entity that is a sub-component of it",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_part",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_variant_part",
      "multivalued": true,
      "inherited": true,
      "owner": "has_variant_part",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "related_condition",
      "definition_uri": "https://w3id.org/biolink/vocab/related_condition",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/GENO_0000790"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/related_condition",
      "multivalued": true,
      "inherited": true,
      "owner": "related_condition",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_sequence_variant_of",
      "definition_uri": "https://w3id.org/biolink/vocab/is_sequence_variant_of",
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_gene_product_sequence_variation_encoded_by_gene_mutant",
        "http://purl.obolibrary.org/obo/NCIT_gene_product_variant_of_gene_product",
        "http://purl.obolibrary.org/obo/OMIM_allelic_variant_of",
        "https://www.wikidata.org/wiki/P3433"
      ],
      "description": "holds between a sequence variant and a genomic entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "SequenceVariant",
      "slot_uri": "https://w3id.org/biolink/vocab/is_sequence_variant_of",
      "multivalued": true,
      "inherited": true,
      "owner": "is_sequence_variant_of",
      "range": "GenomicEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_missense_variant_of",
      "definition_uri": "https://w3id.org/biolink/vocab/is_missense_variant_of",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/SO_0001583",
        "http://translator.ncats.nih.gov/SNPEFF_missense_variant"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/SNPEFF_initiator_codon_variant",
        "http://translator.ncats.nih.gov/SNPEFF_structural_interaction_variant"
      ],
      "description": "holds between a gene  and a sequence variant, such the sequence variant results in a different amino acid sequence but where the length is preserved.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "is_sequence_variant_of",
      "domain": "SequenceVariant",
      "slot_uri": "https://w3id.org/biolink/vocab/is_missense_variant_of",
      "multivalued": true,
      "inherited": true,
      "owner": "is_missense_variant_of",
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_synonymous_variant_of",
      "definition_uri": "https://w3id.org/biolink/vocab/is_synonymous_variant_of",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/SO_0001819",
        "http://translator.ncats.nih.gov/SNPEFF_synonymous_variant"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/SNPEFF_start_retained",
        "http://translator.ncats.nih.gov/SNPEFF_stop_retained_variant"
      ],
      "description": "holds between a sequence variant and a gene, such the sequence variant is in the coding sequence of the gene, but results in the same amino acid sequence",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "is_sequence_variant_of",
      "domain": "SequenceVariant",
      "slot_uri": "https://w3id.org/biolink/vocab/is_synonymous_variant_of",
      "multivalued": true,
      "inherited": true,
      "owner": "is_synonymous_variant_of",
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_nonsense_variant_of",
      "definition_uri": "https://w3id.org/biolink/vocab/is_nonsense_variant_of",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/SNPEFF_stop_gained"
      ],
      "broad_mappings": [
        "http://purl.obolibrary.org/obo/SO_0002054"
      ],
      "description": "holds between a sequence variant and a gene, such the sequence variant results in a premature stop codon",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "is_sequence_variant_of",
      "domain": "SequenceVariant",
      "slot_uri": "https://w3id.org/biolink/vocab/is_nonsense_variant_of",
      "multivalued": true,
      "inherited": true,
      "owner": "is_nonsense_variant_of",
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_frameshift_variant_of",
      "definition_uri": "https://w3id.org/biolink/vocab/is_frameshift_variant_of",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/SO_0001589",
        "http://translator.ncats.nih.gov/SNPEFF_frameshift_variant"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/SNPEFF_start_lost",
        "http://translator.ncats.nih.gov/SNPEFF_stop_lost"
      ],
      "description": "holds between a sequence variant and a gene, such the sequence variant causes a disruption of the translational reading frame, because the number of nucleotides inserted or deleted is not a multiple of three.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "is_sequence_variant_of",
      "domain": "SequenceVariant",
      "slot_uri": "https://w3id.org/biolink/vocab/is_frameshift_variant_of",
      "multivalued": true,
      "inherited": true,
      "owner": "is_frameshift_variant_of",
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_splice_site_variant_of",
      "definition_uri": "https://w3id.org/biolink/vocab/is_splice_site_variant_of",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/SO_0001629"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/SNPEFF_splice_region_variant",
        "http://translator.ncats.nih.gov/SNPEFF_splice_acceptor_variant",
        "http://translator.ncats.nih.gov/SNPEFF_splice_donor_variant"
      ],
      "description": "holds between a sequence variant and a gene, such the sequence variant is in the canonical splice site of one of the gene's exons.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "is_sequence_variant_of",
      "domain": "SequenceVariant",
      "slot_uri": "https://w3id.org/biolink/vocab/is_splice_site_variant_of",
      "multivalued": true,
      "inherited": true,
      "owner": "is_splice_site_variant_of",
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_nearby_variant_of",
      "definition_uri": "https://w3id.org/biolink/vocab/is_nearby_variant_of",
      "exact_mappings": [
        "http://translator.renci.org/GAMMA_0000102"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/SNPEFF_downstream_gene_variant",
        "http://translator.ncats.nih.gov/SNPEFF_upstream_gene_variant"
      ],
      "description": "holds between a sequence variant and a gene sequence that the variant is genomically close to.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "is_sequence_variant_of",
      "domain": "SequenceVariant",
      "slot_uri": "https://w3id.org/biolink/vocab/is_nearby_variant_of",
      "multivalued": true,
      "inherited": true,
      "owner": "is_nearby_variant_of",
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "is_non_coding_variant_of",
      "definition_uri": "https://w3id.org/biolink/vocab/is_non_coding_variant_of",
      "exact_mappings": [
        "http://translator.renci.org/GAMMA_0000103"
      ],
      "narrow_mappings": [
        "http://translator.ncats.nih.gov/SNPEFF_3_prime_UTR_variant",
        "http://translator.ncats.nih.gov/SNPEFF_5_prime_UTR_variant",
        "http://translator.ncats.nih.gov/SNPEFF_5_prime_UTR_premature_start_codon_gain_variant",
        "http://translator.ncats.nih.gov/SNPEFF_non_coding_transcript_exon_variant",
        "http://translator.ncats.nih.gov/SNPEFF_intron_variant"
      ],
      "description": "holds between a sequence variant and a gene, where the variant does not affect the coding sequence",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "is_sequence_variant_of",
      "domain": "SequenceVariant",
      "slot_uri": "https://w3id.org/biolink/vocab/is_non_coding_variant_of",
      "multivalued": true,
      "inherited": true,
      "owner": "is_non_coding_variant_of",
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "disease_has_basis_in",
      "definition_uri": "https://w3id.org/biolink/vocab/disease_has_basis_in",
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/MONDO_disease_has_basis_in_development_of",
        "http://purl.obolibrary.org/obo/MONDO_disease_has_basis_in_accumulation_of"
      ],
      "description": "A relation that holds between a disease and an entity where the state of the entity has contribution to the disease.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/disease_has_basis_in",
      "multivalued": true,
      "inherited": true,
      "owner": "disease_has_basis_in",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "causes_adverse_event",
      "definition_uri": "https://w3id.org/biolink/vocab/causes_adverse_event",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/Aeolus_0000001"
      ],
      "description": "holds between a drug and a disease or phenotype that can be caused by the drug",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "causes",
      "domain": "Drug",
      "slot_uri": "https://w3id.org/biolink/vocab/causes_adverse_event",
      "multivalued": true,
      "inherited": true,
      "owner": "causes_adverse_event",
      "range": "DiseaseOrPhenotypicFeature",
      "@type": "SlotDefinition"
    },
    {
      "name": "contraindicated_for",
      "definition_uri": "https://w3id.org/biolink/vocab/contraindicated_for",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/DrugCentral_0000001",
        "http://kg1endpoint.rtx.ai/contraindicated_for"
      ],
      "description": "Holds between a drug and a disease or phenotype, such that a person with that disease should not be treated with the drug.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "Drug",
      "slot_uri": "https://w3id.org/biolink/vocab/contraindicated_for",
      "multivalued": true,
      "inherited": true,
      "owner": "contraindicated_for",
      "range": "DiseaseOrPhenotypicFeature",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_not_completed",
      "definition_uri": "https://w3id.org/biolink/vocab/has_not_completed",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/CL_has_not_completed"
      ],
      "description": "holds between an entity and a process that the entity is capable of, but has not completed",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_not_completed",
      "multivalued": true,
      "inherited": true,
      "owner": "has_not_completed",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_completed",
      "definition_uri": "https://w3id.org/biolink/vocab/has_completed",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/CL_has_completed",
        "http://kg1endpoint.rtx.ai/has_completed"
      ],
      "description": "holds between an entity and a process that the entity is capable of and has completed",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_completed",
      "multivalued": true,
      "inherited": true,
      "owner": "has_completed",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "decreases_molecular_interaction",
      "definition_uri": "https://w3id.org/biolink/vocab/decreases_molecular_interaction",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_decreases_molecular_interaction_with"
      ],
      "description": "indicates that the source decreases the molecular interaction between the target and some other molecular entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "molecularly_interacts_with",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/decreases_molecular_interaction",
      "multivalued": true,
      "inherited": true,
      "owner": "decreases_molecular_interaction",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "increases_molecular_interaction",
      "definition_uri": "https://w3id.org/biolink/vocab/increases_molecular_interaction",
      "exact_mappings": [
        "http://translator.ncats.nih.gov/CTD_increases_molecular_interaction_with"
      ],
      "description": "indicates that the source increases the molecular interaction between the target and some other molecular entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "molecularly_interacts_with",
      "domain": "MolecularEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/increases_molecular_interaction",
      "multivalued": true,
      "inherited": true,
      "owner": "increases_molecular_interaction",
      "range": "MolecularEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "in_linkage_disequilibrium_with",
      "definition_uri": "https://w3id.org/biolink/vocab/in_linkage_disequilibrium_with",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_C16798"
      ],
      "description": "holds between two sequence variants, the presence of which are correlated in a population",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/in_linkage_disequilibrium_with",
      "multivalued": true,
      "inherited": true,
      "owner": "in_linkage_disequilibrium_with",
      "symmetric": true,
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_increased_amount",
      "definition_uri": "https://w3id.org/biolink/vocab/has_increased_amount",
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/CL_has_high_plasma_membrane_amount"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_increased_amount",
      "multivalued": true,
      "inherited": true,
      "owner": "has_increased_amount",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_decreased_amount",
      "definition_uri": "https://w3id.org/biolink/vocab/has_decreased_amount",
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/CL_has_low_plasma_membrane_amount"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_decreased_amount",
      "multivalued": true,
      "inherited": true,
      "owner": "has_decreased_amount",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "lacks_part",
      "definition_uri": "https://w3id.org/biolink/vocab/lacks_part",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/CL_lacks_part",
        "http://purl.obolibrary.org/obo/PR_lacks_part",
        "http://kg1endpoint.rtx.ai/lacks_part"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/CL_lacks_plasma_membrane_part"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/lacks_part",
      "multivalued": true,
      "inherited": true,
      "owner": "lacks_part",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "develops_from",
      "definition_uri": "https://w3id.org/biolink/vocab/develops_from",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/BTO_develops_from",
        "http://purl.obolibrary.org/obo/DDANAT_develops_from",
        "http://purl.obolibrary.org/obo/FMA_develops_from",
        "http://purl.obolibrary.org/obo/RO_0002202"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002203",
        "http://purl.obolibrary.org/obo/FMA_develops_into"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002207",
        "http://purl.obolibrary.org/obo/RO_0002225",
        "http://purl.obolibrary.org/obo/RO_0002226"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/develops_from",
      "multivalued": true,
      "inherited": true,
      "owner": "develops_from",
      "range": "NamedThing",
      "@type": "SlotDefinition"
    },
    {
      "name": "in_taxon",
      "definition_uri": "https://w3id.org/biolink/vocab/in_taxon",
      "aliases": [
        "instance of"
      ],
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P703"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_is_organism_source_of_gene_product",
        "http://purl.obolibrary.org/obo/NCIT_organism_has_gene"
      ],
      "related_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002162"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_gene_found_in_organism",
        "http://purl.obolibrary.org/obo/NCIT_gene_product_has_organism_source",
        "http://purl.obolibrary.org/obo/RO_0002160"
      ],
      "description": "connects an entity to its taxonomic classification. Only certain kinds of entities can be taxonomically classified; see 'thing with taxon'",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "ThingWithTaxon",
      "slot_uri": "https://w3id.org/biolink/vocab/in_taxon",
      "multivalued": true,
      "inherited": true,
      "owner": "ThingWithTaxon",
      "domain_of": [
        "ThingWithTaxon"
      ],
      "range": "OrganismTaxon",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_molecular_consequence",
      "definition_uri": "https://w3id.org/biolink/vocab/has_molecular_consequence",
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_allele_has_activity"
      ],
      "description": "connects a sequence variant to a class describing the molecular consequence. E.g.  SO:0001583",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "related_to",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/has_molecular_consequence",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "owner": "has_molecular_consequence",
      "range": "OntologyClass",
      "@type": "SlotDefinition"
    },
    {
      "name": "association_slot",
      "definition_uri": "https://w3id.org/biolink/vocab/association_slot",
      "aliases": [
        "edge property",
        "statement property"
      ],
      "description": "any slot that relates an association to another entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "abstract": true,
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/association_slot",
      "owner": "association_slot",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "association_id",
      "definition_uri": "https://w3id.org/biolink/vocab/association_id",
      "description": "A unique identifier for an association",
      "deprecated": "This slot is deprecated in favor of 'id' slot.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "deprecated_element_has_exact_replacement": "id",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/id",
      "identifier": true,
      "alias": "id",
      "owner": "association_id",
      "range": "string",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": [
        {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject",
          "@type": "LocalName"
        },
        {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship",
          "@type": "LocalName"
        }
      ],
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "owner": "Association",
      "domain_of": [
        "Association"
      ],
      "range": "NamedThing",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": [
        {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor",
          "@type": "LocalName"
        },
        {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship",
          "@type": "LocalName"
        }
      ],
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "owner": "Association",
      "domain_of": [
        "Association"
      ],
      "range": "NamedThing",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": [
        {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate",
          "@type": "LocalName"
        },
        {
          "local_name_source": "translator",
          "local_name_value": "predicate",
          "@type": "LocalName"
        }
      ],
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "owner": "Association",
      "domain_of": [
        "Association"
      ],
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "edge_label",
      "definition_uri": "https://w3id.org/biolink/vocab/edge_label",
      "local_names": [
        {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate",
          "@type": "LocalName"
        },
        {
          "local_name_source": "translator",
          "local_name_value": "predicate",
          "@type": "LocalName"
        }
      ],
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "deprecated": "This slot is deprecated in favor of 'predicate' slot.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "deprecated_element_has_exact_replacement": "predicate",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "owner": "edge_label",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "logical_interpretation",
      "definition_uri": "https://w3id.org/biolink/vocab/logical_interpretation",
      "exact_mappings": [
        "https://github.com/cmungall/owlstar/blob/master/owlstar.ttlLogicalInterpretation"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/logical_interpretation",
      "owner": "logical_interpretation",
      "range": "logical_interpretation_enum",
      "@type": "SlotDefinition"
    },
    {
      "name": "relation",
      "id_prefixes": [
        "RO",
        "BSPO",
        "SIO"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/relation",
      "description": "The relation which describes an association between a subject and an object in a more granular manner. Usually this is a term from Relation Ontology, but it can be any edge CURIE.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/relation",
      "owner": "Association",
      "domain_of": [
        "Association"
      ],
      "range": "uriorcurie",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "negated",
      "definition_uri": "https://w3id.org/biolink/vocab/negated",
      "description": "if set to true, then the association is negated i.e. is not true",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/negated",
      "owner": "Association",
      "domain_of": [
        "Association"
      ],
      "range": "boolean",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_confidence_level",
      "definition_uri": "https://w3id.org/biolink/vocab/has_confidence_level",
      "description": "connects an association to a qualitative term denoting the level of confidence",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/has_confidence_level",
      "owner": "has_confidence_level",
      "range": "ConfidenceLevel",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_evidence",
      "definition_uri": "https://w3id.org/biolink/vocab/has_evidence",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002558"
      ],
      "description": "connects an association to an instance of supporting evidence",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/has_evidence",
      "owner": "has_evidence",
      "range": "EvidenceType",
      "@type": "SlotDefinition"
    },
    {
      "name": "provided_by",
      "definition_uri": "https://w3id.org/biolink/vocab/provided_by",
      "exact_mappings": [
        "http://purl.org/pav/providedBy"
      ],
      "description": "connects an association to the agent (person, organization or group) that provided it",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/provided_by",
      "multivalued": true,
      "owner": "Entity",
      "domain_of": [
        "Entity"
      ],
      "range": "Agent",
      "@type": "SlotDefinition"
    },
    {
      "name": "association_type",
      "definition_uri": "https://w3id.org/biolink/vocab/association_type",
      "description": "connects an association to the category of association (e.g. gene to phenotype)",
      "deprecated": "This slot is deprecated in favor of 'category' slot.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "deprecated_element_has_exact_replacement": "category",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/association_type",
      "owner": "association_type",
      "range": "category_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "chi_squared_statistic",
      "definition_uri": "https://w3id.org/biolink/vocab/chi_squared_statistic",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/STATO_0000030"
      ],
      "description": "represents the chi-squared statistic computed from observations",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/chi_squared_statistic",
      "owner": "chi_squared_statistic",
      "range": "float",
      "@type": "SlotDefinition"
    },
    {
      "name": "p_value",
      "definition_uri": "https://w3id.org/biolink/vocab/p_value",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/OBI_0000175",
        "http://purl.obolibrary.org/obo/NCIT_C44185",
        "http://edamontology.org/data_1669"
      ],
      "description": "A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/p_value",
      "owner": "p_value",
      "range": "float",
      "@type": "SlotDefinition"
    },
    {
      "name": "interacting_molecules_category",
      "definition_uri": "https://w3id.org/biolink/vocab/interacting_molecules_category",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/MI_1046"
      ],
      "examples": [
        {
          "value": "MI:1048",
          "description": "smallmolecule-protein",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "values_from": [
        "MI"
      ],
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/interacting_molecules_category",
      "inlined": true,
      "owner": "PairwiseMolecularInteraction",
      "domain_of": [
        "PairwiseMolecularInteraction"
      ],
      "range": "OntologyClass",
      "@type": "SlotDefinition"
    },
    {
      "name": "quantifier_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/quantifier_qualifier",
      "narrow_mappings": [
        "http://loinc.org/rdf/analyzes",
        "http://loinc.org/rdf/measured_by",
        "http://loinc.org/rdf/property_of",
        "https://skr3.nlm.nih.gov/SemMedDBmeasures",
        "http://identifiers.org/umls/measures"
      ],
      "description": "A measurable quantity for the object of the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/quantifier_qualifier",
      "inlined": true,
      "owner": "GeneToExpressionSiteAssociation",
      "domain_of": [
        "GeneExpressionMixin",
        "GeneToExpressionSiteAssociation"
      ],
      "range": "OntologyClass",
      "@type": "SlotDefinition"
    },
    {
      "name": "catalyst_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/catalyst_qualifier",
      "description": "a qualifier that connects an association between two causally connected entities (for example, two chemical entities, or a chemical entity in that changes location) and the gene product, gene, or complex that enables or catalyzes the change.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/catalyst_qualifier",
      "multivalued": true,
      "inlined": true,
      "owner": "ChemicalToChemicalDerivationAssociation",
      "domain_of": [
        "ChemicalToChemicalDerivationAssociation"
      ],
      "range": "MacromolecularMachineMixin",
      "@type": "SlotDefinition"
    },
    {
      "name": "expression_site",
      "definition_uri": "https://w3id.org/biolink/vocab/expression_site",
      "description": "location in which gene or protein expression takes place. May be cell, tissue, or organ.",
      "examples": [
        {
          "value": "UBERON:0002037",
          "description": "cerebellum",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/expression_site",
      "owner": "GeneExpressionMixin",
      "domain_of": [
        "GeneExpressionMixin"
      ],
      "range": "AnatomicalEntity",
      "@type": "SlotDefinition"
    },
    {
      "name": "stage_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/stage_qualifier",
      "description": "stage during which gene or protein expression of takes place.",
      "examples": [
        {
          "value": "UBERON:0000069",
          "description": "larval stage",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/stage_qualifier",
      "owner": "GeneToExpressionSiteAssociation",
      "domain_of": [
        "GeneExpressionMixin",
        "GeneToExpressionSiteAssociation"
      ],
      "range": "LifeStage",
      "@type": "SlotDefinition"
    },
    {
      "name": "phenotypic_state",
      "definition_uri": "https://w3id.org/biolink/vocab/phenotypic_state",
      "description": "in experiments (e.g. gene expression) assaying diseased or unhealthy tissue, the phenotypic state can be put here, e.g. MONDO ID. For healthy tissues, use XXX.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/phenotypic_state",
      "owner": "GeneExpressionMixin",
      "domain_of": [
        "GeneExpressionMixin"
      ],
      "range": "DiseaseOrPhenotypicFeature",
      "@type": "SlotDefinition"
    },
    {
      "name": "qualifiers",
      "definition_uri": "https://w3id.org/biolink/vocab/qualifiers",
      "local_names": [
        {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation qualifier",
          "@type": "LocalName"
        }
      ],
      "description": "connects an association to qualifiers that modify or qualify the meaning of that association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "singular_name": "qualifier",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/qualifiers",
      "multivalued": true,
      "inlined": true,
      "owner": "Association",
      "domain_of": [
        "Association"
      ],
      "range": "OntologyClass",
      "@type": "SlotDefinition"
    },
    {
      "name": "frequency_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/frequency_qualifier",
      "description": "a qualifier used in a phenotypic association to state how frequent the phenotype is observed in the subject",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/frequency_qualifier",
      "owner": "FrequencyQualifierMixin",
      "domain_of": [
        "FrequencyQualifierMixin"
      ],
      "range": "frequency_value",
      "@type": "SlotDefinition"
    },
    {
      "name": "severity_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/severity_qualifier",
      "description": "a qualifier used in a phenotypic association to state how severe the phenotype is in the subject",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/severity_qualifier",
      "inlined": true,
      "owner": "EntityToFeatureOrDiseaseQualifiersMixin",
      "domain_of": [
        "EntityToFeatureOrDiseaseQualifiersMixin"
      ],
      "range": "SeverityValue",
      "@type": "SlotDefinition"
    },
    {
      "name": "sex_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/sex_qualifier",
      "description": "a qualifier used in a phenotypic association to state whether the association is specific to a particular sex.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/sex_qualifier",
      "inlined": true,
      "owner": "EntityToPhenotypicFeatureAssociationMixin",
      "domain_of": [
        "EntityToPhenotypicFeatureAssociationMixin"
      ],
      "range": "BiologicalSex",
      "@type": "SlotDefinition"
    },
    {
      "name": "onset_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/onset_qualifier",
      "description": "a qualifier used in a phenotypic association to state when the phenotype appears is in the subject",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/onset_qualifier",
      "inlined": true,
      "owner": "EntityToFeatureOrDiseaseQualifiersMixin",
      "domain_of": [
        "EntityToFeatureOrDiseaseQualifiersMixin"
      ],
      "range": "Onset",
      "@type": "SlotDefinition"
    },
    {
      "name": "clinical_modifier_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/clinical_modifier_qualifier",
      "description": "Used to characterize and specify the phenotypic abnormalities defined in the Phenotypic abnormality subontology, with respect to severity, laterality, age of onset, and other aspects",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/clinical_modifier_qualifier",
      "inlined": true,
      "owner": "clinical_modifier_qualifier",
      "range": "ClinicalModifier",
      "@type": "SlotDefinition"
    },
    {
      "name": "sequence_variant_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/sequence_variant_qualifier",
      "description": "a qualifier used in an association with the variant",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/sequence_variant_qualifier",
      "owner": "GeneHasVariantThatContributesToDiseaseAssociation",
      "domain_of": [
        "GeneHasVariantThatContributesToDiseaseAssociation"
      ],
      "range": "SequenceVariant",
      "@type": "SlotDefinition"
    },
    {
      "name": "publications",
      "definition_uri": "https://w3id.org/biolink/vocab/publications",
      "description": "connects an association to publications supporting the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "singular_name": "publication",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/publications",
      "multivalued": true,
      "owner": "Association",
      "domain_of": [
        "Association"
      ],
      "range": "Publication",
      "@type": "SlotDefinition"
    },
    {
      "name": "associated_environmental_context",
      "definition_uri": "https://w3id.org/biolink/vocab/associated_environmental_context",
      "description": "An attribute that can be applied to an association where the association holds between two entities located or occurring in a particular environment. For example, two microbial taxa may interact in the context of a human gut; a disease may give rise to a particular phenotype in a particular environmental exposure.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/associated_environmental_context",
      "owner": "OrganismTaxonToOrganismTaxonInteraction",
      "domain_of": [
        "OrganismTaxonToOrganismTaxonInteraction"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "sequence_localization_attribute",
      "definition_uri": "https://w3id.org/biolink/vocab/sequence_localization_attribute",
      "description": "An attribute that can be applied to a genome sequence localization edge. These edges connect a genomic entity such as an exon to an entity such as a chromosome. Edge properties are used to ascribe specific positional information and other metadata to the localization. In pragmatic terms this can be thought of as columns in a GFF3 line.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "association_slot",
      "domain": "GenomicSequenceLocalization",
      "slot_uri": "https://w3id.org/biolink/vocab/sequence_localization_attribute",
      "owner": "sequence_localization_attribute",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "interbase_coordinate",
      "definition_uri": "https://w3id.org/biolink/vocab/interbase_coordinate",
      "description": "A position in interbase coordinates. This is applied to a sequence localization edge.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "sequence_localization_attribute",
      "domain": "GenomicSequenceLocalization",
      "slot_uri": "https://w3id.org/biolink/vocab/interbase_coordinate",
      "owner": "interbase_coordinate",
      "range": "integer",
      "@type": "SlotDefinition"
    },
    {
      "name": "start_interbase_coordinate",
      "definition_uri": "https://w3id.org/biolink/vocab/start_interbase_coordinate",
      "description": "The position at which the subject genomic entity starts on the chromosome or other entity to which it is located on.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "interbase_coordinate",
      "domain": "GenomicSequenceLocalization",
      "slot_uri": "https://w3id.org/biolink/vocab/start_interbase_coordinate",
      "owner": "GenomicSequenceLocalization",
      "domain_of": [
        "GenomicSequenceLocalization"
      ],
      "range": "integer",
      "@type": "SlotDefinition"
    },
    {
      "name": "end_interbase_coordinate",
      "definition_uri": "https://w3id.org/biolink/vocab/end_interbase_coordinate",
      "description": "The position at which the subject genomic entity ends on the chromosome or other entity to which it is located on.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "interbase_coordinate",
      "domain": "GenomicSequenceLocalization",
      "slot_uri": "https://w3id.org/biolink/vocab/end_interbase_coordinate",
      "owner": "GenomicSequenceLocalization",
      "domain_of": [
        "GenomicSequenceLocalization"
      ],
      "range": "integer",
      "@type": "SlotDefinition"
    },
    {
      "name": "genome_build",
      "definition_uri": "https://w3id.org/biolink/vocab/genome_build",
      "description": "The version of the genome on which a feature is located. For example, GRCh38 for Homo sapiens.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "sequence_localization_attribute",
      "domain": "GenomicSequenceLocalization",
      "slot_uri": "https://w3id.org/biolink/vocab/genome_build",
      "owner": "GenomicSequenceLocalization",
      "domain_of": [
        "GenomicSequenceLocalization"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "strand",
      "definition_uri": "https://w3id.org/biolink/vocab/strand",
      "description": "The strand on which a feature is located. Has a value of '+' (sense strand or forward strand) or '-' (anti-sense strand or reverse strand).",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "sequence_localization_attribute",
      "domain": "GenomicSequenceLocalization",
      "slot_uri": "https://w3id.org/biolink/vocab/strand",
      "owner": "GenomicSequenceLocalization",
      "domain_of": [
        "GenomicSequenceLocalization"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "phase",
      "definition_uri": "https://w3id.org/biolink/vocab/phase",
      "description": "The phase for a coding sequence entity. For example, phase of a CDS as represented in a GFF3 with a value of 0, 1 or 2.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "sequence_localization_attribute",
      "domain": "CodingSequence",
      "slot_uri": "https://w3id.org/biolink/vocab/phase",
      "owner": "phase",
      "domain_of": [
        "GenomicSequenceLocalization"
      ],
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "has_taxonomic_rank",
      "mappings": [
        "https://www.wikidata.org/wiki/P105"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "slot_uri": "https://w3id.org/biolink/vocab/has_taxonomic_rank",
      "inlined": true,
      "range": "TaxonomicRank",
      "@type": "SlotDefinition"
    },
    {
      "name": "attribute_name",
      "definition_uri": "https://w3id.org/biolink/vocab/name",
      "aliases": [
        "label",
        "display name",
        "title"
      ],
      "mappings": [
        "http://www.w3.org/2000/01/rdf-schema#label"
      ],
      "exact_mappings": [
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#Name",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Name"
      ],
      "narrow_mappings": [
        "http://purl.org/dc/terms/title",
        "https://www.wikidata.org/wiki/Property:P1476"
      ],
      "description": "The human-readable 'attribute name' can be set to a string which reflects its context of interpretation, e.g. SEPIO evidence/provenance/confidence annotation or it can default to the name associated with the 'has attribute type' slot ontology term.",
      "in_subset": [
        "translator_minimal",
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "name",
      "domain": "Attribute",
      "slot_uri": "http://www.w3.org/2000/01/rdf-schema#label",
      "alias": "name",
      "owner": "Attribute",
      "domain_of": [
        "Attribute"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "name",
      "range": "label_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "named_thing_category",
      "definition_uri": "https://w3id.org/biolink/vocab/category",
      "description": "Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class.\n * In a neo4j database this MAY correspond to the neo4j label tag.\n * In an RDF database it should be a biolink model class URI.\nThis field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values `biolink:Protein`, `biolink:GeneProduct`, `biolink:MolecularEntity`, ...\nIn an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature `f` may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing}",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "category",
      "domain": "NamedThing",
      "slot_uri": "https://w3id.org/biolink/vocab/category",
      "multivalued": true,
      "alias": "category",
      "owner": "NamedThing",
      "domain_of": [
        "NamedThing"
      ],
      "is_class_field": true,
      "is_usage_slot": true,
      "usage_slot_name": "category",
      "range": "NamedThing",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_has_taxonomic_rank",
      "mappings": [
        "https://www.wikidata.org/wiki/P105"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_taxonomic_rank",
      "domain": "OrganismTaxon",
      "slot_uri": "https://w3id.org/biolink/vocab/has_taxonomic_rank",
      "inlined": true,
      "alias": "has taxonomic rank",
      "owner": "OrganismTaxon",
      "domain_of": [
        "OrganismTaxon"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has taxonomic rank",
      "range": "TaxonomicRank",
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_subclass_of",
      "definition_uri": "https://w3id.org/biolink/vocab/subclass_of",
      "exact_mappings": [
        "http://www.w3.org/2000/01/rdf-schema#subClassOf",
        "https://skr3.nlm.nih.gov/SemMedDBIS_A",
        "https://skr3.nlm.nih.gov/SemMedDBisa",
        "https://www.wikidata.org/wiki/Property:P279",
        "https://www.ebi.ac.uk/chembl/mechanism/inspect/subset_of",
        "http://purl.obolibrary.org/obo/GO_isa",
        "http://identifiers.org/mesh/isa",
        "http://kg1endpoint.rtx.ai/subclass_of",
        "http://purl.bioontology.org/ontology/RXNORM/isa",
        "https://www.nlm.nih.gov/research/umls/sourcereleasedocs/current/VANDF/isa"
      ],
      "close_mappings": [
        "http://loinc.org/rdf/class_of",
        "http://loinc.org/rdf/has_class"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/CHEBI_has_parent_hydride",
        "http://loinc.org/rdf/has_archetype",
        "http://loinc.org/rdf/has_parent_group",
        "http://loinc.org/rdf/is_presence_guidance_for",
        "http://purl.obolibrary.org/obo/NCIT_gene_product_has_chemical_classification",
        "http://purl.obolibrary.org/obo/NCIT_R36",
        "http://purl.obolibrary.org/obo/NCIT_R42",
        "http://purl.obolibrary.org/obo/NCIT_A16",
        "http://purl.obolibrary.org/obo/NCIT_A11",
        "http://purl.obolibrary.org/obo/NCIT_A14",
        "http://purl.obolibrary.org/obo/NCIT_A3",
        "http://purl.bioontology.org/ontology/NDDF/has_dose_form",
        "http://purl.obolibrary.org/obo/intersection_of",
        "http://purl.bioontology.org/ontology/RXNORM/has_dose_form",
        "http://purl.bioontology.org/ontology/RXNORM/has_doseformgroup",
        "http://purl.obolibrary.org/obo/SNOMED_entire_anatomy_structure_of",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form",
        "http://www.w3.org/2000/01/rdf-schema#subPropertyOf"
      ],
      "description": "subclass of holds between two taxa, e.g. human subclass of mammal",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subclass_of",
      "domain": "OrganismTaxon",
      "slot_uri": "https://w3id.org/biolink/vocab/subclass_of",
      "multivalued": true,
      "inherited": true,
      "alias": "subclass of",
      "owner": "OrganismTaxon",
      "domain_of": [
        "OrganismTaxon"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subclass of",
      "range": "OrganismTaxon",
      "@type": "SlotDefinition"
    },
    {
      "name": "agent_id",
      "definition_uri": "https://w3id.org/biolink/vocab/id",
      "exact_mappings": [
        "https://www.alliancegenome.org/primaryId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#ID",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_ID"
      ],
      "description": "Different classes of agents have distinct preferred identifiers. For publishers, use the ISBN publisher code. See https://grp.isbn-international.org/ for publisher code lookups. For editors, authors and  individual providers, use the individual's ORCID if available; Otherwise, a ScopusID, ResearchID or Google Scholar ID ('GSID') may be used if the author ORCID is unknown. Institutional agents could be identified by an International Standard Name Identifier ('ISNI') code.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "id",
      "values_from": [
        "isbn",
        "ORCID",
        "ScopusID",
        "ResearchID",
        "GSID",
        "isni"
      ],
      "domain": "Agent",
      "slot_uri": "https://w3id.org/biolink/vocab/id",
      "identifier": true,
      "alias": "id",
      "owner": "Agent",
      "domain_of": [
        "Agent"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "id",
      "range": "string",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "agent_name",
      "definition_uri": "https://w3id.org/biolink/vocab/name",
      "aliases": [
        "label",
        "display name",
        "title"
      ],
      "mappings": [
        "http://www.w3.org/2000/01/rdf-schema#label"
      ],
      "exact_mappings": [
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#Name",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Name"
      ],
      "narrow_mappings": [
        "http://purl.org/dc/terms/title",
        "https://www.wikidata.org/wiki/Property:P1476"
      ],
      "description": "it is recommended that an author's 'name' property be formatted as \"surname, firstname initial.\"",
      "in_subset": [
        "translator_minimal",
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "name",
      "domain": "Agent",
      "slot_uri": "http://www.w3.org/2000/01/rdf-schema#label",
      "alias": "name",
      "owner": "Agent",
      "domain_of": [
        "Agent"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "name",
      "range": "label_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "publication_id",
      "definition_uri": "https://w3id.org/biolink/vocab/id",
      "exact_mappings": [
        "https://www.alliancegenome.org/primaryId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#ID",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_ID"
      ],
      "description": "Different kinds of publication subtypes will have different preferred identifiers (curies when feasible). Precedence of identifiers for scientific articles is as follows: PMID if available; DOI if not; actual alternate CURIE otherwise. Enclosing publications (i.e. referenced by 'published in' node property) such as books and journals, should have industry-standard identifier such as from ISBN and ISSN.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "id",
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/id",
      "identifier": true,
      "alias": "id",
      "owner": "Publication",
      "domain_of": [
        "Publication"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "id",
      "range": "string",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "publication_name",
      "definition_uri": "https://w3id.org/biolink/vocab/name",
      "aliases": [
        "label",
        "display name",
        "title"
      ],
      "mappings": [
        "http://www.w3.org/2000/01/rdf-schema#label"
      ],
      "exact_mappings": [
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#Name",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Name"
      ],
      "narrow_mappings": [
        "http://purl.org/dc/terms/title",
        "https://www.wikidata.org/wiki/Property:P1476"
      ],
      "description": "the 'title' of the publication is generally recorded in the 'name' property (inherited from NamedThing). The field name 'title' is now also tagged as an acceptable alias for the node property 'name' (just in case).",
      "in_subset": [
        "translator_minimal",
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "name",
      "domain": "Publication",
      "slot_uri": "http://www.w3.org/2000/01/rdf-schema#label",
      "alias": "name",
      "owner": "Publication",
      "domain_of": [
        "Publication"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "name",
      "range": "label_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "publication_type",
      "definition_uri": "https://w3id.org/biolink/vocab/type",
      "mappings": [
        "http://purl.org/dc/terms/type"
      ],
      "exact_mappings": [
        "https://www.alliancegenome.org/soTermId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#type",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Type"
      ],
      "description": "Ontology term for publication type may be drawn from Dublin Core types (https://www.dublincore.org/specifications/dublin-core/dcmi-type-vocabulary/), FRBR-aligned Bibliographic Ontology (https://sparontologies.github.io/fabio/current/fabio.html), the MESH publication types (https://www.nlm.nih.gov/mesh/pubtypes.html), the Confederation of Open Access Repositories (COAR) Controlled Vocabulary for Resource Type Genres (http://vocabularies.coar-repositories.org/documentation/resource_types/), Wikidata (https://www.wikidata.org/wiki/Wikidata:Publication_types), or equivalent publication type ontology. When a given publication type ontology term is used within a given knowledge graph, then the CURIE identified term must be documented in the graph as a concept node of biolink:category biolink:OntologyClass.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "type",
      "values_from": [
        "dctypes",
        "fabio",
        "MESH_PUB",
        "COAR_RESOURCE",
        "WIKIDATA"
      ],
      "domain": "Publication",
      "slot_uri": "http://purl.org/dc/terms/type",
      "alias": "type",
      "owner": "Publication",
      "domain_of": [
        "Publication"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "type",
      "range": "string",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "publication_pages",
      "definition_uri": "https://w3id.org/biolink/vocab/pages",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P304"
      ],
      "description": "When a 2-tuple of page numbers are provided, they represent the start and end page of the publication within its parent publication context. For books, this may be set to the total number of pages of the book.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "pages",
      "domain": "Publication",
      "slot_uri": "https://w3id.org/biolink/vocab/pages",
      "multivalued": true,
      "alias": "pages",
      "owner": "Publication",
      "domain_of": [
        "Publication"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "pages",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "book_id",
      "definition_uri": "https://w3id.org/biolink/vocab/id",
      "exact_mappings": [
        "https://www.alliancegenome.org/primaryId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#ID",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_ID"
      ],
      "description": "Books should have industry-standard identifier such as from ISBN.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "publication_id",
      "domain": "Book",
      "slot_uri": "https://w3id.org/biolink/vocab/id",
      "identifier": true,
      "alias": "id",
      "owner": "Book",
      "domain_of": [
        "Book"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "id",
      "range": "string",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "book_type",
      "definition_uri": "https://w3id.org/biolink/vocab/type",
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#type"
      ],
      "exact_mappings": [
        "https://www.alliancegenome.org/soTermId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#type",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Type"
      ],
      "description": "Should generally be set to an ontology class defined term for 'book'.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "publication_type",
      "domain": "Book",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#type",
      "alias": "type",
      "owner": "Book",
      "domain_of": [
        "Book"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "type",
      "range": "string",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "book_chapter_published_in",
      "definition_uri": "https://w3id.org/biolink/vocab/published_in",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P1433"
      ],
      "description": "The enclosing parent book containing the chapter should have industry-standard identifier from ISBN.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "published_in",
      "values_from": [
        "NLMID",
        "issn",
        "isbn"
      ],
      "domain": "BookChapter",
      "slot_uri": "https://w3id.org/biolink/vocab/published_in",
      "alias": "published in",
      "owner": "BookChapter",
      "domain_of": [
        "BookChapter"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "published in",
      "range": "uriorcurie",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "serial_id",
      "definition_uri": "https://w3id.org/biolink/vocab/id",
      "exact_mappings": [
        "https://www.alliancegenome.org/primaryId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#ID",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_ID"
      ],
      "description": "Serials (journals) should have industry-standard identifier such as from ISSN.",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "publication_id",
      "domain": "Serial",
      "slot_uri": "https://w3id.org/biolink/vocab/id",
      "identifier": true,
      "alias": "id",
      "owner": "Serial",
      "domain_of": [
        "Serial"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "id",
      "range": "string",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "serial_type",
      "definition_uri": "https://w3id.org/biolink/vocab/type",
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#type"
      ],
      "exact_mappings": [
        "https://www.alliancegenome.org/soTermId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#type",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Type"
      ],
      "description": "Should generally be set to an ontology class defined term for 'serial' or 'journal'.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "publication_type",
      "domain": "Serial",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#type",
      "alias": "type",
      "owner": "Serial",
      "domain_of": [
        "Serial"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "type",
      "range": "string",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "article_published_in",
      "definition_uri": "https://w3id.org/biolink/vocab/published_in",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P1433"
      ],
      "description": "The enclosing parent serial containing the article should have industry-standard identifier from ISSN.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "published_in",
      "values_from": [
        "NLMID",
        "issn",
        "isbn"
      ],
      "domain": "Article",
      "slot_uri": "https://w3id.org/biolink/vocab/published_in",
      "alias": "published in",
      "owner": "Article",
      "domain_of": [
        "Article"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "published in",
      "range": "uriorcurie",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "article_iso_abbreviation",
      "definition_uri": "https://w3id.org/biolink/vocab/iso_abbreviation",
      "exact_mappings": [
        "https://www.wikidata.org/wiki/Property:P1160"
      ],
      "description": "Optional value, if used locally as a convenience, is set to the iso abbreviation of the 'published in' parent.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "iso_abbreviation",
      "domain": "Article",
      "slot_uri": "https://w3id.org/biolink/vocab/iso_abbreviation",
      "alias": "iso abbreviation",
      "owner": "Article",
      "domain_of": [
        "Article"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "iso abbreviation",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "molecular_activity_has_input",
      "definition_uri": "https://w3id.org/biolink/vocab/has_input",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002233",
        "https://skr3.nlm.nih.gov/SemMedDBUSES",
        "https://skr3.nlm.nih.gov/SemMedDBuses"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002352"
      ],
      "narrow_mappings": [
        "http://loinc.org/rdf/has_fragments_for_synonyms",
        "http://loinc.org/rdf/has_system",
        "http://smpdb.ca/pathways/#has_left_element",
        "http://purl.obolibrary.org/obo/RO_0002590",
        "http://purl.obolibrary.org/obo/RO_0004009",
        "http://purl.obolibrary.org/obo/SNOMED_has_finding_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_precondition",
        "http://purl.obolibrary.org/obo/SNOMED_has_specimen_source_identity",
        "http://purl.obolibrary.org/obo/SNOMED_has_specimen_substance",
        "http://purl.obolibrary.org/obo/SNOMED_uses_access_device",
        "http://purl.obolibrary.org/obo/SNOMED_uses_device",
        "http://purl.obolibrary.org/obo/SNOMED_uses_energy",
        "http://purl.obolibrary.org/obo/SNOMED_uses_substance"
      ],
      "description": "A chemical entity that is the input for the reaction",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_input",
      "domain": "MolecularActivity",
      "slot_uri": "https://w3id.org/biolink/vocab/has_input",
      "multivalued": true,
      "inherited": true,
      "alias": "has input",
      "owner": "MolecularActivity",
      "domain_of": [
        "MolecularActivity"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has input",
      "range": "ChemicalSubstance",
      "@type": "SlotDefinition"
    },
    {
      "name": "molecular_activity_has_output",
      "definition_uri": "https://w3id.org/biolink/vocab/has_output",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002234"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002353",
        "http://purl.obolibrary.org/obo/RO_0002354",
        "http://kg1endpoint.rtx.ai/output_of"
      ],
      "narrow_mappings": [
        "http://purl.obolibrary.org/obo/NCIT_R31",
        "http://purl.obolibrary.org/obo/OBI_0000299",
        "http://smpdb.ca/pathways/#has_right_element",
        "http://purl.obolibrary.org/obo/RO_0002296",
        "http://purl.obolibrary.org/obo/RO_0002297",
        "http://purl.obolibrary.org/obo/RO_0002298",
        "http://purl.obolibrary.org/obo/RO_0002299",
        "http://purl.obolibrary.org/obo/RO_0002588",
        "http://purl.obolibrary.org/obo/RO_0004008"
      ],
      "description": "A chemical entity that is the output for the reaction",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_output",
      "domain": "MolecularActivity",
      "slot_uri": "https://w3id.org/biolink/vocab/has_output",
      "multivalued": true,
      "inherited": true,
      "alias": "has output",
      "owner": "MolecularActivity",
      "domain_of": [
        "MolecularActivity"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has output",
      "range": "ChemicalSubstance",
      "@type": "SlotDefinition"
    },
    {
      "name": "molecular_activity_enabled_by",
      "definition_uri": "https://w3id.org/biolink/vocab/enabled_by",
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/RO_0002333"
      ],
      "description": "The gene product, gene, or complex that catalyzes the reaction",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "enabled_by",
      "domain": "MolecularActivity",
      "slot_uri": "https://w3id.org/biolink/vocab/enabled_by",
      "multivalued": true,
      "inherited": true,
      "inlined": true,
      "alias": "enabled by",
      "owner": "MolecularActivity",
      "domain_of": [
        "MolecularActivity"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "enabled by",
      "range": "MacromolecularMachineMixin",
      "@type": "SlotDefinition"
    },
    {
      "name": "organismal_entity_has_attribute",
      "definition_uri": "https://w3id.org/biolink/vocab/has_attribute",
      "exact_mappings": [
        "http://semanticscience.org/resource/SIO_000008"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/OBI_0001927"
      ],
      "narrow_mappings": [
        "http://purl.org/oban/association_has_subject_property",
        "http://purl.org/oban/association_has_object_property",
        "https://www.ama-assn.org/practice-management/cpt/has_possibly_included_panel_element",
        "http://identifiers.org/drugbank/category",
        "http://www.ebi.ac.uk/efo/EFO_is_executed_in",
        "http://www.ebi.ac.uk/ancestro/ancestro_0301",
        "http://loinc.org/rdf/has_action_guidance",
        "http://loinc.org/rdf/has_adjustment",
        "http://loinc.org/rdf/has_aggregation_view",
        "http://loinc.org/rdf/has_approach_guidance",
        "http://loinc.org/rdf/has_divisor",
        "http://loinc.org/rdf/has_exam",
        "http://loinc.org/rdf/has_method",
        "http://loinc.org/rdf/has_modality_subtype",
        "http://loinc.org/rdf/has_object_guidance",
        "http://loinc.org/rdf/has_scale",
        "http://loinc.org/rdf/has_suffix",
        "http://loinc.org/rdf/has_time_aspect",
        "http://loinc.org/rdf/has_time_modifier",
        "http://loinc.org/rdf/has_timing_of",
        "http://purl.obolibrary.org/obo/NCIT_disease_is_grade",
        "http://purl.obolibrary.org/obo/NCIT_disease_is_stage",
        "http://purl.obolibrary.org/obo/NCIT_eo_disease_has_property_or_attribute",
        "http://purl.obolibrary.org/obo/NCIT_has_data_element",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_administration_method",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_basic_dose_form",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_intended_site",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_release_characteristics",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_state_of_matter",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_transformation",
        "http://purl.obolibrary.org/obo/NCIT_is_qualified_by",
        "http://purl.obolibrary.org/obo/NCIT_qualifier_applies_to",
        "http://purl.obolibrary.org/obo/NCIT_role_has_domain",
        "http://purl.obolibrary.org/obo/NCIT_role_has_range",
        "http://purl.obolibrary.org/obo/INO_0000154",
        "http://www.ebi.ac.uk/ancestro/ancestro_0308",
        "http://purl.obolibrary.org/obo/OMIM_has_inheritance_type",
        "http://www.orpha.net/ORDO/Orphanet_C016",
        "http://www.orpha.net/ORDO/Orphanet_C017",
        "http://purl.obolibrary.org/obo/RO_0000053",
        "http://purl.obolibrary.org/obo/RO_0000086",
        "http://purl.obolibrary.org/obo/RO_0000087",
        "http://purl.obolibrary.org/obo/SNOMED_has_access",
        "http://purl.obolibrary.org/obo/SNOMED_has_clinical_course",
        "http://purl.obolibrary.org/obo/SNOMED_has_count_of_base_of_active_ingredient",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_administration_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_release_characteristic",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_transformation",
        "http://purl.obolibrary.org/obo/SNOMED_has_finding_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_finding_informer",
        "http://purl.obolibrary.org/obo/SNOMED_has_inherent_attribute",
        "http://purl.obolibrary.org/obo/SNOMED_has_intent",
        "http://purl.obolibrary.org/obo/SNOMED_has_interpretation",
        "http://purl.obolibrary.org/obo/SNOMED_has_laterality",
        "http://purl.obolibrary.org/obo/SNOMED_has_measurement_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_priority",
        "http://purl.obolibrary.org/obo/SNOMED_has_procedure_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_process_duration",
        "http://purl.obolibrary.org/obo/SNOMED_has_property",
        "http://purl.obolibrary.org/obo/SNOMED_has_revision_status",
        "http://purl.obolibrary.org/obo/SNOMED_has_scale_type",
        "http://purl.obolibrary.org/obo/SNOMED_has_severity",
        "http://purl.obolibrary.org/obo/SNOMED_has_specimen",
        "http://purl.obolibrary.org/obo/SNOMED_has_state_of_matter",
        "http://purl.obolibrary.org/obo/SNOMED_has_subject_relationship_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_surgical_approach",
        "http://purl.obolibrary.org/obo/SNOMED_has_technique",
        "http://purl.obolibrary.org/obo/SNOMED_has_temporal_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_time_aspect",
        "http://purl.obolibrary.org/obo/SNOMED_has_units",
        "http://identifiers.org/umls/has_structural_class",
        "http://identifiers.org/umls/has_supported_concept_property",
        "http://identifiers.org/umls/has_supported_concept_relationship",
        "http://identifiers.org/umls/may_be_qualified_by"
      ],
      "description": "may often be an organism attribute",
      "in_subset": [
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_attribute",
      "domain": "OrganismalEntity",
      "slot_uri": "https://w3id.org/biolink/vocab/has_attribute",
      "multivalued": true,
      "inlined": true,
      "alias": "has attribute",
      "owner": "OrganismalEntity",
      "domain_of": [
        "OrganismalEntity"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has attribute",
      "range": "Attribute",
      "@type": "SlotDefinition"
    },
    {
      "name": "macromolecular_machine_mixin_name",
      "definition_uri": "https://w3id.org/biolink/vocab/name",
      "aliases": [
        "label",
        "display name",
        "title"
      ],
      "mappings": [
        "http://www.w3.org/2000/01/rdf-schema#label"
      ],
      "exact_mappings": [
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#Name",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Name"
      ],
      "narrow_mappings": [
        "http://purl.org/dc/terms/title",
        "https://www.wikidata.org/wiki/Property:P1476"
      ],
      "description": "genes are typically designated by a short symbol and a full name. We map the symbol to the default display name and use an additional slot for full name",
      "in_subset": [
        "translator_minimal",
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "name",
      "domain": "MacromolecularMachineMixin",
      "slot_uri": "http://www.w3.org/2000/01/rdf-schema#label",
      "alias": "name",
      "owner": "MacromolecularMachineMixin",
      "domain_of": [
        "MacromolecularMachineMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "name",
      "range": "symbol_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "sequence_variant_has_gene",
      "definition_uri": "https://w3id.org/biolink/vocab/has_gene",
      "description": "Each allele can be associated with any number of genes",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_gene",
      "domain": "SequenceVariant",
      "slot_uri": "https://w3id.org/biolink/vocab/has_gene",
      "multivalued": true,
      "alias": "has gene",
      "owner": "SequenceVariant",
      "domain_of": [
        "SequenceVariant"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has gene",
      "range": "Gene",
      "@type": "SlotDefinition"
    },
    {
      "name": "sequence_variant_has_biological_sequence",
      "definition_uri": "https://w3id.org/biolink/vocab/has_biological_sequence",
      "description": "The state of the sequence w.r.t a reference sequence",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_biological_sequence",
      "domain": "SequenceVariant",
      "slot_uri": "https://w3id.org/biolink/vocab/has_biological_sequence",
      "alias": "has biological sequence",
      "owner": "SequenceVariant",
      "domain_of": [
        "SequenceVariant"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has biological sequence",
      "range": "biological_sequence",
      "@type": "SlotDefinition"
    },
    {
      "name": "sequence_variant_id",
      "definition_uri": "https://w3id.org/biolink/vocab/id",
      "exact_mappings": [
        "https://www.alliancegenome.org/primaryId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#ID",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_ID"
      ],
      "description": "A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI",
      "examples": [
        {
          "value": "ZFIN:ZDB-ALT-980203-1091",
          "description": "ti282a allele from ZFIN",
          "@type": "Example"
        },
        {
          "value": "ClinVarVariant:17681",
          "description": "NM_007294.3(BRCA1):c.2521C>T (p.Arg841Trp)",
          "@type": "Example"
        }
      ],
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "id",
      "domain": "SequenceVariant",
      "slot_uri": "https://w3id.org/biolink/vocab/id",
      "identifier": true,
      "alias": "id",
      "owner": "SequenceVariant",
      "domain_of": [
        "SequenceVariant"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "id",
      "range": "string",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "clinical_measurement_has_attribute_type",
      "definition_uri": "https://w3id.org/biolink/vocab/has_attribute_type",
      "narrow_mappings": [
        "http://loinc.org/rdf/has_modality_type",
        "http://loinc.org/rdf/has_view_type"
      ],
      "description": "connects an attribute to a class that describes it",
      "in_subset": [
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_attribute_type",
      "values_from": [
        "EFO",
        "LOINC"
      ],
      "domain": "ClinicalMeasurement",
      "slot_uri": "https://w3id.org/biolink/vocab/has_attribute_type",
      "inlined": true,
      "alias": "has attribute type",
      "owner": "ClinicalMeasurement",
      "domain_of": [
        "ClinicalMeasurement"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has attribute type",
      "range": "OntologyClass",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "clinical_finding_has_attribute",
      "definition_uri": "https://w3id.org/biolink/vocab/has_attribute",
      "exact_mappings": [
        "http://semanticscience.org/resource/SIO_000008"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/OBI_0001927"
      ],
      "narrow_mappings": [
        "http://purl.org/oban/association_has_subject_property",
        "http://purl.org/oban/association_has_object_property",
        "https://www.ama-assn.org/practice-management/cpt/has_possibly_included_panel_element",
        "http://identifiers.org/drugbank/category",
        "http://www.ebi.ac.uk/efo/EFO_is_executed_in",
        "http://www.ebi.ac.uk/ancestro/ancestro_0301",
        "http://loinc.org/rdf/has_action_guidance",
        "http://loinc.org/rdf/has_adjustment",
        "http://loinc.org/rdf/has_aggregation_view",
        "http://loinc.org/rdf/has_approach_guidance",
        "http://loinc.org/rdf/has_divisor",
        "http://loinc.org/rdf/has_exam",
        "http://loinc.org/rdf/has_method",
        "http://loinc.org/rdf/has_modality_subtype",
        "http://loinc.org/rdf/has_object_guidance",
        "http://loinc.org/rdf/has_scale",
        "http://loinc.org/rdf/has_suffix",
        "http://loinc.org/rdf/has_time_aspect",
        "http://loinc.org/rdf/has_time_modifier",
        "http://loinc.org/rdf/has_timing_of",
        "http://purl.obolibrary.org/obo/NCIT_disease_is_grade",
        "http://purl.obolibrary.org/obo/NCIT_disease_is_stage",
        "http://purl.obolibrary.org/obo/NCIT_eo_disease_has_property_or_attribute",
        "http://purl.obolibrary.org/obo/NCIT_has_data_element",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_administration_method",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_basic_dose_form",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_intended_site",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_release_characteristics",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_state_of_matter",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_transformation",
        "http://purl.obolibrary.org/obo/NCIT_is_qualified_by",
        "http://purl.obolibrary.org/obo/NCIT_qualifier_applies_to",
        "http://purl.obolibrary.org/obo/NCIT_role_has_domain",
        "http://purl.obolibrary.org/obo/NCIT_role_has_range",
        "http://purl.obolibrary.org/obo/INO_0000154",
        "http://www.ebi.ac.uk/ancestro/ancestro_0308",
        "http://purl.obolibrary.org/obo/OMIM_has_inheritance_type",
        "http://www.orpha.net/ORDO/Orphanet_C016",
        "http://www.orpha.net/ORDO/Orphanet_C017",
        "http://purl.obolibrary.org/obo/RO_0000053",
        "http://purl.obolibrary.org/obo/RO_0000086",
        "http://purl.obolibrary.org/obo/RO_0000087",
        "http://purl.obolibrary.org/obo/SNOMED_has_access",
        "http://purl.obolibrary.org/obo/SNOMED_has_clinical_course",
        "http://purl.obolibrary.org/obo/SNOMED_has_count_of_base_of_active_ingredient",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_administration_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_release_characteristic",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_transformation",
        "http://purl.obolibrary.org/obo/SNOMED_has_finding_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_finding_informer",
        "http://purl.obolibrary.org/obo/SNOMED_has_inherent_attribute",
        "http://purl.obolibrary.org/obo/SNOMED_has_intent",
        "http://purl.obolibrary.org/obo/SNOMED_has_interpretation",
        "http://purl.obolibrary.org/obo/SNOMED_has_laterality",
        "http://purl.obolibrary.org/obo/SNOMED_has_measurement_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_priority",
        "http://purl.obolibrary.org/obo/SNOMED_has_procedure_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_process_duration",
        "http://purl.obolibrary.org/obo/SNOMED_has_property",
        "http://purl.obolibrary.org/obo/SNOMED_has_revision_status",
        "http://purl.obolibrary.org/obo/SNOMED_has_scale_type",
        "http://purl.obolibrary.org/obo/SNOMED_has_severity",
        "http://purl.obolibrary.org/obo/SNOMED_has_specimen",
        "http://purl.obolibrary.org/obo/SNOMED_has_state_of_matter",
        "http://purl.obolibrary.org/obo/SNOMED_has_subject_relationship_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_surgical_approach",
        "http://purl.obolibrary.org/obo/SNOMED_has_technique",
        "http://purl.obolibrary.org/obo/SNOMED_has_temporal_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_time_aspect",
        "http://purl.obolibrary.org/obo/SNOMED_has_units",
        "http://identifiers.org/umls/has_structural_class",
        "http://identifiers.org/umls/has_supported_concept_property",
        "http://identifiers.org/umls/has_supported_concept_relationship",
        "http://identifiers.org/umls/may_be_qualified_by"
      ],
      "description": "connects any entity to an attribute",
      "in_subset": [
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_attribute",
      "domain": "ClinicalFinding",
      "slot_uri": "https://w3id.org/biolink/vocab/has_attribute",
      "multivalued": true,
      "inlined": true,
      "alias": "has attribute",
      "owner": "ClinicalFinding",
      "domain_of": [
        "ClinicalFinding"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has attribute",
      "range": "ClinicalAttribute",
      "@type": "SlotDefinition"
    },
    {
      "name": "socioeconomic_exposure_has_attribute",
      "definition_uri": "https://w3id.org/biolink/vocab/has_attribute",
      "exact_mappings": [
        "http://semanticscience.org/resource/SIO_000008"
      ],
      "close_mappings": [
        "http://purl.obolibrary.org/obo/OBI_0001927"
      ],
      "narrow_mappings": [
        "http://purl.org/oban/association_has_subject_property",
        "http://purl.org/oban/association_has_object_property",
        "https://www.ama-assn.org/practice-management/cpt/has_possibly_included_panel_element",
        "http://identifiers.org/drugbank/category",
        "http://www.ebi.ac.uk/efo/EFO_is_executed_in",
        "http://www.ebi.ac.uk/ancestro/ancestro_0301",
        "http://loinc.org/rdf/has_action_guidance",
        "http://loinc.org/rdf/has_adjustment",
        "http://loinc.org/rdf/has_aggregation_view",
        "http://loinc.org/rdf/has_approach_guidance",
        "http://loinc.org/rdf/has_divisor",
        "http://loinc.org/rdf/has_exam",
        "http://loinc.org/rdf/has_method",
        "http://loinc.org/rdf/has_modality_subtype",
        "http://loinc.org/rdf/has_object_guidance",
        "http://loinc.org/rdf/has_scale",
        "http://loinc.org/rdf/has_suffix",
        "http://loinc.org/rdf/has_time_aspect",
        "http://loinc.org/rdf/has_time_modifier",
        "http://loinc.org/rdf/has_timing_of",
        "http://purl.obolibrary.org/obo/NCIT_disease_is_grade",
        "http://purl.obolibrary.org/obo/NCIT_disease_is_stage",
        "http://purl.obolibrary.org/obo/NCIT_eo_disease_has_property_or_attribute",
        "http://purl.obolibrary.org/obo/NCIT_has_data_element",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_administration_method",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_basic_dose_form",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_intended_site",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_release_characteristics",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_state_of_matter",
        "http://purl.obolibrary.org/obo/NCIT_has_pharmaceutical_transformation",
        "http://purl.obolibrary.org/obo/NCIT_is_qualified_by",
        "http://purl.obolibrary.org/obo/NCIT_qualifier_applies_to",
        "http://purl.obolibrary.org/obo/NCIT_role_has_domain",
        "http://purl.obolibrary.org/obo/NCIT_role_has_range",
        "http://purl.obolibrary.org/obo/INO_0000154",
        "http://www.ebi.ac.uk/ancestro/ancestro_0308",
        "http://purl.obolibrary.org/obo/OMIM_has_inheritance_type",
        "http://www.orpha.net/ORDO/Orphanet_C016",
        "http://www.orpha.net/ORDO/Orphanet_C017",
        "http://purl.obolibrary.org/obo/RO_0000053",
        "http://purl.obolibrary.org/obo/RO_0000086",
        "http://purl.obolibrary.org/obo/RO_0000087",
        "http://purl.obolibrary.org/obo/SNOMED_has_access",
        "http://purl.obolibrary.org/obo/SNOMED_has_clinical_course",
        "http://purl.obolibrary.org/obo/SNOMED_has_count_of_base_of_active_ingredient",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_administration_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_release_characteristic",
        "http://purl.obolibrary.org/obo/SNOMED_has_dose_form_transformation",
        "http://purl.obolibrary.org/obo/SNOMED_has_finding_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_finding_informer",
        "http://purl.obolibrary.org/obo/SNOMED_has_inherent_attribute",
        "http://purl.obolibrary.org/obo/SNOMED_has_intent",
        "http://purl.obolibrary.org/obo/SNOMED_has_interpretation",
        "http://purl.obolibrary.org/obo/SNOMED_has_laterality",
        "http://purl.obolibrary.org/obo/SNOMED_has_measurement_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_method",
        "http://purl.obolibrary.org/obo/SNOMED_has_priority",
        "http://purl.obolibrary.org/obo/SNOMED_has_procedure_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_process_duration",
        "http://purl.obolibrary.org/obo/SNOMED_has_property",
        "http://purl.obolibrary.org/obo/SNOMED_has_revision_status",
        "http://purl.obolibrary.org/obo/SNOMED_has_scale_type",
        "http://purl.obolibrary.org/obo/SNOMED_has_severity",
        "http://purl.obolibrary.org/obo/SNOMED_has_specimen",
        "http://purl.obolibrary.org/obo/SNOMED_has_state_of_matter",
        "http://purl.obolibrary.org/obo/SNOMED_has_subject_relationship_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_surgical_approach",
        "http://purl.obolibrary.org/obo/SNOMED_has_technique",
        "http://purl.obolibrary.org/obo/SNOMED_has_temporal_context",
        "http://purl.obolibrary.org/obo/SNOMED_has_time_aspect",
        "http://purl.obolibrary.org/obo/SNOMED_has_units",
        "http://identifiers.org/umls/has_structural_class",
        "http://identifiers.org/umls/has_supported_concept_property",
        "http://identifiers.org/umls/has_supported_concept_relationship",
        "http://identifiers.org/umls/may_be_qualified_by"
      ],
      "description": "connects any entity to an attribute",
      "in_subset": [
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_attribute",
      "domain": "SocioeconomicExposure",
      "slot_uri": "https://w3id.org/biolink/vocab/has_attribute",
      "multivalued": true,
      "inlined": true,
      "alias": "has attribute",
      "owner": "SocioeconomicExposure",
      "domain_of": [
        "SocioeconomicExposure"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has attribute",
      "range": "SocioeconomicAttribute",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "association_type",
      "definition_uri": "https://w3id.org/biolink/vocab/type",
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#type"
      ],
      "exact_mappings": [
        "https://www.alliancegenome.org/soTermId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#type",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Type"
      ],
      "description": "rdf:type of biolink:Association should be fixed at rdf:Statement",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "type",
      "domain": "Association",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#type",
      "alias": "type",
      "owner": "Association",
      "domain_of": [
        "Association"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "type",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "association_category",
      "definition_uri": "https://w3id.org/biolink/vocab/category",
      "description": "Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class.\n * In a neo4j database this MAY correspond to the neo4j label tag.\n * In an RDF database it should be a biolink model class URI.\nThis field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values `biolink:Protein`, `biolink:GeneProduct`, `biolink:MolecularEntity`, ...\nIn an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature `f` may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing}",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "category",
      "domain": "Association",
      "slot_uri": "https://w3id.org/biolink/vocab/category",
      "multivalued": true,
      "alias": "category",
      "owner": "Association",
      "domain_of": [
        "Association"
      ],
      "is_class_field": true,
      "is_usage_slot": true,
      "usage_slot_name": "category",
      "range": "category_type",
      "@type": "SlotDefinition"
    },
    {
      "name": "contributor_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "information content entity which an agent has helped realise",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "ContributorAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "ContributorAssociation",
      "domain_of": [
        "ContributorAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "InformationContentEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "contributor_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "generally one of the predicate values 'provider', 'publisher', 'editor' or 'author'",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "ContributorAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "ContributorAssociation",
      "domain_of": [
        "ContributorAssociation"
      ],
      "subproperty_of": "contributor",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "contributor_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "agent helping to realise the given entity (e.g. such as a publication)",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "ContributorAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "ContributorAssociation",
      "domain_of": [
        "ContributorAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "Agent",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "contributor_association_qualifiers",
      "definition_uri": "https://w3id.org/biolink/vocab/qualifiers",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation qualifier"
        }
      },
      "description": "this field can be used to annotate special characteristics of an agent relationship, such as the fact that a given author agent of a publication is the 'corresponding author'",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "qualifiers",
      "singular_name": "qualifier",
      "domain": "ContributorAssociation",
      "slot_uri": "https://w3id.org/biolink/vocab/qualifiers",
      "multivalued": true,
      "inlined": true,
      "alias": "qualifiers",
      "owner": "ContributorAssociation",
      "domain_of": [
        "ContributorAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "qualifiers",
      "range": "OntologyClass",
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_genotype_part_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "GenotypeToGenotypePartAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "GenotypeToGenotypePartAssociation",
      "domain_of": [
        "GenotypeToGenotypePartAssociation"
      ],
      "subproperty_of": "has_variant_part",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_genotype_part_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "parent genotype",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GenotypeToGenotypePartAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "GenotypeToGenotypePartAssociation",
      "domain_of": [
        "GenotypeToGenotypePartAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Genotype",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_genotype_part_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "child genotype",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "GenotypeToGenotypePartAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "GenotypeToGenotypePartAssociation",
      "domain_of": [
        "GenotypeToGenotypePartAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "Genotype",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_gene_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "the relationship type used to connect genotype to gene",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "GenotypeToGeneAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "GenotypeToGeneAssociation",
      "domain_of": [
        "GenotypeToGeneAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_gene_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "parent genotype",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GenotypeToGeneAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "GenotypeToGeneAssociation",
      "domain_of": [
        "GenotypeToGeneAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Genotype",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_gene_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "gene implicated in genotype",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "GenotypeToGeneAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "GenotypeToGeneAssociation",
      "domain_of": [
        "GenotypeToGeneAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "Gene",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_variant_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "the relationship type used to connect genotype to gene",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "GenotypeToVariantAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "GenotypeToVariantAssociation",
      "domain_of": [
        "GenotypeToVariantAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_variant_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "parent genotype",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GenotypeToVariantAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "GenotypeToVariantAssociation",
      "domain_of": [
        "GenotypeToVariantAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Genotype",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_variant_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "gene implicated in genotype",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "GenotypeToVariantAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "GenotypeToVariantAssociation",
      "domain_of": [
        "GenotypeToVariantAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "SequenceVariant",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_gene_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the subject gene in the association. If the relation is symmetric, subject vs object is arbitrary. We allow a gene product to stand as a proxy for the gene or vice versa.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GeneToGeneAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "inlined": true,
      "alias": "subject",
      "owner": "GeneToGeneAssociation",
      "domain_of": [
        "GeneToGeneAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_gene_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the object gene in the association. If the relation is symmetric, subject vs object is arbitrary. We allow a gene product to stand as a proxy for the gene or vice versa.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "GeneToGeneAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "inlined": true,
      "alias": "object",
      "owner": "GeneToGeneAssociation",
      "domain_of": [
        "GeneToGeneAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_gene_homology_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "homology relationship type",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "GeneToGeneHomologyAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "GeneToGeneHomologyAssociation",
      "domain_of": [
        "GeneToGeneHomologyAssociation"
      ],
      "subproperty_of": "homologous_to",
      "symmetric": true,
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_expression_mixin_quantifier_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/quantifier_qualifier",
      "narrow_mappings": [
        "http://loinc.org/rdf/analyzes",
        "http://loinc.org/rdf/measured_by",
        "http://loinc.org/rdf/property_of",
        "https://skr3.nlm.nih.gov/SemMedDBmeasures",
        "http://identifiers.org/umls/measures"
      ],
      "description": "Optional quantitative value indicating degree of expression.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "quantifier_qualifier",
      "domain": "GeneExpressionMixin",
      "slot_uri": "https://w3id.org/biolink/vocab/quantifier_qualifier",
      "inlined": true,
      "alias": "quantifier qualifier",
      "owner": "GeneExpressionMixin",
      "domain_of": [
        "GeneExpressionMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "quantifier qualifier",
      "range": "OntologyClass",
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_gene_coexpression_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "GeneToGeneCoexpressionAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "GeneToGeneCoexpressionAssociation",
      "domain_of": [
        "GeneToGeneCoexpressionAssociation"
      ],
      "subproperty_of": "coexpressed_with",
      "symmetric": true,
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "pairwise_gene_to_gene_interaction_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "PairwiseGeneToGeneInteraction",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "PairwiseGeneToGeneInteraction",
      "domain_of": [
        "PairwiseGeneToGeneInteraction"
      ],
      "subproperty_of": "interacts_with",
      "symmetric": true,
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "pairwise_gene_to_gene_interaction_relation",
      "id_prefixes": [
        "RO",
        "BSPO",
        "SIO"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/relation",
      "description": "interaction relationship type",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "relation",
      "values_from": [
        "ro",
        "mi"
      ],
      "domain": "PairwiseGeneToGeneInteraction",
      "slot_uri": "https://w3id.org/biolink/vocab/relation",
      "alias": "relation",
      "owner": "PairwiseGeneToGeneInteraction",
      "domain_of": [
        "PairwiseGeneToGeneInteraction"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "relation",
      "range": "uriorcurie",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "pairwise_molecular_interaction_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "gene_to_gene_association_subject",
      "domain": "PairwiseMolecularInteraction",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "PairwiseMolecularInteraction",
      "domain_of": [
        "PairwiseMolecularInteraction"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "MolecularEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "pairwise_molecular_interaction_id",
      "definition_uri": "https://w3id.org/biolink/vocab/id",
      "exact_mappings": [
        "https://www.alliancegenome.org/primaryId",
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#ID",
        "https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_ID"
      ],
      "description": "identifier for the interaction. This may come from an interaction database such as IMEX.",
      "examples": [
        {
          "value": "WB:WBInteraction000538741",
          "@type": "Example"
        }
      ],
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "id",
      "values_from": [
        "IMEX",
        "BioGRID"
      ],
      "domain": "PairwiseMolecularInteraction",
      "slot_uri": "https://w3id.org/biolink/vocab/id",
      "identifier": true,
      "alias": "id",
      "owner": "PairwiseMolecularInteraction",
      "domain_of": [
        "PairwiseMolecularInteraction"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "id",
      "range": "string",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "pairwise_molecular_interaction_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "pairwise_gene_to_gene_interaction_predicate",
      "domain": "PairwiseMolecularInteraction",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "PairwiseMolecularInteraction",
      "domain_of": [
        "PairwiseMolecularInteraction"
      ],
      "subproperty_of": "molecularly_interacts_with",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "pairwise_molecular_interaction_relation",
      "id_prefixes": [
        "RO",
        "BSPO",
        "SIO"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/relation",
      "description": "interaction relationship type",
      "examples": [
        {
          "value": "RO:0002447",
          "description": "the subject molecular phosphorylates the object molecule",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "pairwise_gene_to_gene_interaction_relation",
      "values_from": [
        "ro",
        "mi"
      ],
      "domain": "PairwiseMolecularInteraction",
      "slot_uri": "https://w3id.org/biolink/vocab/relation",
      "alias": "relation",
      "owner": "PairwiseMolecularInteraction",
      "domain_of": [
        "PairwiseMolecularInteraction"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "relation",
      "range": "uriorcurie",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "pairwise_molecular_interaction_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "gene_to_gene_association_object",
      "domain": "PairwiseMolecularInteraction",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "PairwiseMolecularInteraction",
      "domain_of": [
        "PairwiseMolecularInteraction"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "MolecularEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "cell_line_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "CellLineToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "CellLineToEntityAssociationMixin",
      "domain_of": [
        "CellLineToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "CellLine",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "cell_line_to_disease_or_phenotypic_feature_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "CellLineToDiseaseOrPhenotypicFeatureAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "CellLineToDiseaseOrPhenotypicFeatureAssociation",
      "domain_of": [
        "CellLineToDiseaseOrPhenotypicFeatureAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "DiseaseOrPhenotypicFeature",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "molecular_entity_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the molecular entity that is an interactor",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "MolecularEntityToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "MolecularEntityToEntityAssociationMixin",
      "domain_of": [
        "MolecularEntityToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "MolecularEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "drug_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the drug that is an interactor",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "molecular_entity_to_entity_association_mixin_subject",
      "domain": "DrugToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "DrugToEntityAssociationMixin",
      "domain_of": [
        "DrugToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Drug",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "chemical_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the chemical substance or entity that is an interactor",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "molecular_entity_to_entity_association_mixin_subject",
      "domain": "ChemicalToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "ChemicalToEntityAssociationMixin",
      "domain_of": [
        "ChemicalToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "ChemicalSubstance",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "case_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the case (e.g. patient) that has the property",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "CaseToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "CaseToEntityAssociationMixin",
      "domain_of": [
        "CaseToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Case",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "chemical_to_chemical_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the chemical element that is the target of the statement",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "ChemicalToChemicalAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "ChemicalToChemicalAssociation",
      "domain_of": [
        "ChemicalToChemicalAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "ChemicalSubstance",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "chemical_to_chemical_derivation_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the upstream chemical entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "ChemicalToChemicalDerivationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "ChemicalToChemicalDerivationAssociation",
      "domain_of": [
        "ChemicalToChemicalDerivationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "ChemicalSubstance",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "chemical_to_chemical_derivation_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the downstream chemical entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "chemical_to_chemical_association_object",
      "domain": "ChemicalToChemicalDerivationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "ChemicalToChemicalDerivationAssociation",
      "domain_of": [
        "ChemicalToChemicalDerivationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "ChemicalSubstance",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "chemical_to_chemical_derivation_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "ChemicalToChemicalDerivationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "ChemicalToChemicalDerivationAssociation",
      "domain_of": [
        "ChemicalToChemicalDerivationAssociation"
      ],
      "subproperty_of": "derives_into",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "chemical_to_chemical_derivation_association_catalyst_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/catalyst_qualifier",
      "description": "this connects the derivation edge to the molecular entity that catalyzes the reaction that causes the subject chemical to transform into the object chemical.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "catalyst_qualifier",
      "domain": "ChemicalToChemicalDerivationAssociation",
      "slot_uri": "https://w3id.org/biolink/vocab/catalyst_qualifier",
      "multivalued": true,
      "inlined": true,
      "alias": "catalyst qualifier",
      "owner": "ChemicalToChemicalDerivationAssociation",
      "domain_of": [
        "ChemicalToChemicalDerivationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "catalyst qualifier",
      "range": "MacromolecularMachineMixin",
      "@type": "SlotDefinition"
    },
    {
      "name": "chemical_to_disease_or_phenotypic_feature_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the disease or phenotype that is affected by the chemical",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "ChemicalToDiseaseOrPhenotypicFeatureAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "ChemicalToDiseaseOrPhenotypicFeatureAssociation",
      "domain_of": [
        "ChemicalToDiseaseOrPhenotypicFeatureAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "DiseaseOrPhenotypicFeature",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "chemical_to_pathway_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the pathway that is affected by the chemical",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "ChemicalToPathwayAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "ChemicalToPathwayAssociation",
      "domain_of": [
        "ChemicalToPathwayAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "Pathway",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "chemical_to_gene_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the gene or gene product that is affected by the chemical.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "ChemicalToGeneAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "inlined": true,
      "alias": "object",
      "owner": "ChemicalToGeneAssociation",
      "domain_of": [
        "ChemicalToGeneAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "drug_to_gene_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the gene or gene product that is affected by the drug",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "DrugToGeneAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "inlined": true,
      "alias": "object",
      "owner": "DrugToGeneAssociation",
      "domain_of": [
        "DrugToGeneAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "material_sample_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the material sample being described",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "MaterialSampleToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "MaterialSampleToEntityAssociationMixin",
      "domain_of": [
        "MaterialSampleToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "MaterialSample",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "material_sample_derivation_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the material sample being described",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "MaterialSampleDerivationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "MaterialSampleDerivationAssociation",
      "domain_of": [
        "MaterialSampleDerivationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "MaterialSample",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "material_sample_derivation_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the material entity the sample was derived from. This may be another material sample, or any other material entity, including for example an organism, a geographic feature, or some environmental material.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "MaterialSampleDerivationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "MaterialSampleDerivationAssociation",
      "domain_of": [
        "MaterialSampleDerivationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "NamedThing",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "material_sample_derivation_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "derivation relationship",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "MaterialSampleDerivationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "MaterialSampleDerivationAssociation",
      "domain_of": [
        "MaterialSampleDerivationAssociation"
      ],
      "subproperty_of": "derives_from",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "disease_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "disease class",
      "examples": [
        {
          "value": "MONDO:0017314",
          "description": "Ehlers-Danlos syndrome, vascular type",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "values_from": [
        "mondo",
        "omim",
        "orphanet",
        "ncit",
        "doid"
      ],
      "domain": "DiseaseToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "DiseaseToEntityAssociationMixin",
      "domain_of": [
        "DiseaseToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Disease",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "entity_to_exposure_event_association_mixin_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "EntityToExposureEventAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "inlined": true,
      "alias": "object",
      "owner": "EntityToExposureEventAssociationMixin",
      "domain_of": [
        "EntityToExposureEventAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "ExposureEvent",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "exposure_event_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "ExposureEventToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "inlined": true,
      "alias": "subject",
      "owner": "ExposureEventToEntityAssociationMixin",
      "domain_of": [
        "ExposureEventToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "ExposureEvent",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "entity_to_outcome_association_mixin_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "EntityToOutcomeAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "inlined": true,
      "alias": "object",
      "owner": "EntityToOutcomeAssociationMixin",
      "domain_of": [
        "EntityToOutcomeAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "Outcome",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "entity_to_phenotypic_feature_association_mixin_description",
      "definition_uri": "https://w3id.org/biolink/vocab/description",
      "aliases": [
        "definition"
      ],
      "mappings": [
        "http://purl.org/dc/terms/description"
      ],
      "exact_mappings": [
        "http://purl.obolibrary.org/obo/IAO_0000115",
        "https://www.w3.org/TR/skos-reference/#definitions"
      ],
      "narrow_mappings": [
        "https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#Description"
      ],
      "description": "A description of specific aspects of this phenotype, not otherwise covered by the phenotype ontology class",
      "in_subset": [
        "translator_minimal"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "description",
      "domain": "EntityToPhenotypicFeatureAssociationMixin",
      "slot_uri": "http://purl.org/dc/terms/description",
      "alias": "description",
      "owner": "EntityToPhenotypicFeatureAssociationMixin",
      "domain_of": [
        "EntityToPhenotypicFeatureAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "description",
      "range": "narrative_text",
      "@type": "SlotDefinition"
    },
    {
      "name": "entity_to_phenotypic_feature_association_mixin_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "phenotypic class",
      "examples": [
        {
          "value": "HP:0002487",
          "description": "Hyperkinesis",
          "@type": "Example"
        },
        {
          "value": "WBPhenotype:0000180",
          "description": "axon morphology variant",
          "@type": "Example"
        },
        {
          "value": "MP:0001569",
          "description": "abnormal circulating bilirubin level",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "values_from": [
        "upheno",
        "hp",
        "mp",
        "wbphenotype"
      ],
      "domain": "EntityToPhenotypicFeatureAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "EntityToPhenotypicFeatureAssociationMixin",
      "domain_of": [
        "EntityToPhenotypicFeatureAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "PhenotypicFeature",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "entity_to_disease_association_mixin_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "disease",
      "examples": [
        {
          "value": "MONDO:0020066",
          "description": "Ehlers-Danlos syndrome",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "EntityToDiseaseAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "EntityToDiseaseAssociationMixin",
      "domain_of": [
        "EntityToDiseaseAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "Disease",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "disease_or_phenotypic_feature_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "disease or phenotype",
      "examples": [
        {
          "value": "MONDO:0017314",
          "description": "Ehlers-Danlos syndrome, vascular type",
          "@type": "Example"
        },
        {
          "value": "MP:0013229",
          "description": "abnormal brain ventricle size",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "DiseaseOrPhenotypicFeatureToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "DiseaseOrPhenotypicFeatureToEntityAssociationMixin",
      "domain_of": [
        "DiseaseOrPhenotypicFeatureToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "DiseaseOrPhenotypicFeature",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "disease_or_phenotypic_feature_association_to_location_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "DiseaseOrPhenotypicFeatureAssociationToLocationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "DiseaseOrPhenotypicFeatureAssociationToLocationAssociation",
      "domain_of": [
        "DiseaseOrPhenotypicFeatureAssociationToLocationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "AnatomicalEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "disease_or_phenotypic_feature_to_location_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "anatomical entity in which the disease or feature is found.",
      "examples": [
        {
          "value": "UBERON:0002048",
          "description": "lung",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "DiseaseOrPhenotypicFeatureToLocationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "DiseaseOrPhenotypicFeatureToLocationAssociation",
      "domain_of": [
        "DiseaseOrPhenotypicFeatureToLocationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "AnatomicalEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "entity_to_disease_or_phenotypic_feature_association_mixin_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "disease or phenotype",
      "examples": [
        {
          "value": "MONDO:0017314",
          "description": "Ehlers-Danlos syndrome, vascular type",
          "@type": "Example"
        },
        {
          "value": "MP:0013229",
          "description": "abnormal brain ventricle size",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "EntityToDiseaseOrPhenotypicFeatureAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "EntityToDiseaseOrPhenotypicFeatureAssociationMixin",
      "domain_of": [
        "EntityToDiseaseOrPhenotypicFeatureAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "DiseaseOrPhenotypicFeature",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "genotype that is the subject of the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GenotypeToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "GenotypeToEntityAssociationMixin",
      "domain_of": [
        "GenotypeToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Genotype",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_phenotypic_feature_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "GenotypeToPhenotypicFeatureAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "GenotypeToPhenotypicFeatureAssociation",
      "domain_of": [
        "GenotypeToPhenotypicFeatureAssociation"
      ],
      "subproperty_of": "has_phenotype",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_phenotypic_feature_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "genotype that is associated with the phenotypic feature",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GenotypeToPhenotypicFeatureAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "GenotypeToPhenotypicFeatureAssociation",
      "domain_of": [
        "GenotypeToPhenotypicFeatureAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Genotype",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "exposure_event_to_phenotypic_feature_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "ExposureEventToPhenotypicFeatureAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "inlined": true,
      "alias": "subject",
      "owner": "ExposureEventToPhenotypicFeatureAssociation",
      "domain_of": [
        "ExposureEventToPhenotypicFeatureAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "ExposureEvent",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "behavior_to_behavioral_feature_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "behavior that is the subject of the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "BehaviorToBehavioralFeatureAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "BehaviorToBehavioralFeatureAssociation",
      "domain_of": [
        "BehaviorToBehavioralFeatureAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Behavior",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "behavior_to_behavioral_feature_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "behavioral feature that is the object of the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "BehaviorToBehavioralFeatureAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "BehaviorToBehavioralFeatureAssociation",
      "domain_of": [
        "BehaviorToBehavioralFeatureAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "BehavioralFeature",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "gene that is the subject of the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GeneToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "inlined": true,
      "alias": "subject",
      "owner": "GeneToEntityAssociationMixin",
      "domain_of": [
        "GeneToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "a sequence variant in which the allele state is associated with some other entity",
      "examples": [
        {
          "value": "ClinVar:38077",
          "description": "ClinVar representation of NM_000059.3(BRCA2):c.7007G>A (p.Arg2336His)",
          "@type": "Example"
        },
        {
          "value": "ClinGen:CA024716",
          "description": "chr13:g.32921033G>C (hg19) in ClinGen",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "VariantToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "VariantToEntityAssociationMixin",
      "domain_of": [
        "VariantToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "SequenceVariant",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_phenotypic_feature_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "gene in which variation is correlated with the phenotypic feature",
      "examples": [
        {
          "value": "HGNC:2197",
          "description": "COL1A1 (Human)",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GeneToPhenotypicFeatureAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "inlined": true,
      "alias": "subject",
      "owner": "GeneToPhenotypicFeatureAssociation",
      "domain_of": [
        "GeneToPhenotypicFeatureAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_disease_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "gene in which variation is correlated with the disease, may be protective or causative or associative, or as a model",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GeneToDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "inlined": true,
      "alias": "subject",
      "owner": "GeneToDiseaseAssociation",
      "domain_of": [
        "GeneToDiseaseAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_gene_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "VariantToGeneAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "VariantToGeneAssociation",
      "domain_of": [
        "VariantToGeneAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "Gene",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_gene_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "VariantToGeneAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "VariantToGeneAssociation",
      "domain_of": [
        "VariantToGeneAssociation"
      ],
      "subproperty_of": "genetic_association",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_gene_expression_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "variant_to_gene_association_predicate",
      "domain": "VariantToGeneExpressionAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "VariantToGeneExpressionAssociation",
      "domain_of": [
        "VariantToGeneExpressionAssociation"
      ],
      "subproperty_of": "affects_expression_of",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_population_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "an allele that has a certain frequency in a given population",
      "examples": [
        {
          "value": "NC_000017.11:g.43051071A>T",
          "description": "17:41203088 A/C in gnomad",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "VariantToPopulationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "VariantToPopulationAssociation",
      "domain_of": [
        "VariantToPopulationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "SequenceVariant",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_population_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the population that is observed to have the frequency",
      "examples": [
        {
          "value": "HANCESTRO:0010",
          "description": "African",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "VariantToPopulationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "VariantToPopulationAssociation",
      "domain_of": [
        "VariantToPopulationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "PopulationOfIndividualOrganisms",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_population_association_has_quotient",
      "definition_uri": "https://w3id.org/biolink/vocab/has_quotient",
      "description": "frequency of allele in population, expressed as a number with allele divided by number in reference population, aka allele frequency",
      "examples": [
        {
          "value": "0.0001666",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_quotient",
      "domain": "VariantToPopulationAssociation",
      "slot_uri": "https://w3id.org/biolink/vocab/has_quotient",
      "alias": "has quotient",
      "owner": "VariantToPopulationAssociation",
      "domain_of": [
        "VariantToPopulationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has quotient",
      "range": "double",
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_population_association_has_count",
      "definition_uri": "https://w3id.org/biolink/vocab/has_count",
      "exact_mappings": [
        "http://loinc.org/rdf/has_count"
      ],
      "description": "number in object population that carry a particular allele, aka allele count",
      "examples": [
        {
          "value": "4",
          "description": "4 individuals in gnomad set",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_count",
      "domain": "VariantToPopulationAssociation",
      "slot_uri": "https://w3id.org/biolink/vocab/has_count",
      "alias": "has count",
      "owner": "VariantToPopulationAssociation",
      "domain_of": [
        "VariantToPopulationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has count",
      "range": "integer",
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_population_association_has_total",
      "definition_uri": "https://w3id.org/biolink/vocab/has_total",
      "description": "number all populations that carry a particular allele, aka allele number",
      "examples": [
        {
          "value": "24014",
          "description": "24014 individuals in gnomad set",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "has_total",
      "domain": "VariantToPopulationAssociation",
      "slot_uri": "https://w3id.org/biolink/vocab/has_total",
      "alias": "has total",
      "owner": "VariantToPopulationAssociation",
      "domain_of": [
        "VariantToPopulationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "has total",
      "range": "integer",
      "@type": "SlotDefinition"
    },
    {
      "name": "population_to_population_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the population that form the subject of the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "PopulationToPopulationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "PopulationToPopulationAssociation",
      "domain_of": [
        "PopulationToPopulationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "PopulationOfIndividualOrganisms",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "population_to_population_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the population that form the object of the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "PopulationToPopulationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "PopulationToPopulationAssociation",
      "domain_of": [
        "PopulationToPopulationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "PopulationOfIndividualOrganisms",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "population_to_population_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A relationship type that holds between the subject and object populations. Standard mereological relations can be used. E.g. subject part-of object, subject overlaps object. Derivation relationships can also be used",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "PopulationToPopulationAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "PopulationToPopulationAssociation",
      "domain_of": [
        "PopulationToPopulationAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_phenotypic_feature_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "a sequence variant in which the allele state is associated in some way with the phenotype state",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "VariantToPhenotypicFeatureAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "VariantToPhenotypicFeatureAssociation",
      "domain_of": [
        "VariantToPhenotypicFeatureAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "SequenceVariant",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_disease_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "a sequence variant in which the allele state is associated in some way with the disease state",
      "examples": [
        {
          "value": "ClinVar:52241",
          "description": "NM_000059.3(BRCA2):c.7007G>C (p.Arg2336Pro)",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "VariantToDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "VariantToDiseaseAssociation",
      "domain_of": [
        "VariantToDiseaseAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "NamedThing",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_disease_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "E.g. is pathogenic for",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "VariantToDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "VariantToDiseaseAssociation",
      "domain_of": [
        "VariantToDiseaseAssociation"
      ],
      "subproperty_of": "related_condition",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_to_disease_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "a disease that is associated with that variant",
      "examples": [
        {
          "value": "MONDO:0016419",
          "description": "hereditary breast cancer",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "VariantToDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "VariantToDiseaseAssociation",
      "domain_of": [
        "VariantToDiseaseAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "NamedThing",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_disease_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "a genotype that is associated in some way with a disease state",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GenotypeToDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "GenotypeToDiseaseAssociation",
      "domain_of": [
        "GenotypeToDiseaseAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "NamedThing",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_disease_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "E.g. is pathogenic for",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "GenotypeToDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "GenotypeToDiseaseAssociation",
      "domain_of": [
        "GenotypeToDiseaseAssociation"
      ],
      "subproperty_of": "related_condition",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_to_disease_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "a disease that is associated with that genotype",
      "examples": [
        {
          "value": "MONDO:0016419",
          "description": "hereditary breast cancer",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "GenotypeToDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "GenotypeToDiseaseAssociation",
      "domain_of": [
        "GenotypeToDiseaseAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "NamedThing",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "model_to_disease_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "The entity that serves as the model of the disease. This may be an organism, a strain of organism, a genotype or variant that exhibits similar features, or a gene that when mutated exhibits features of the disease",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "ModelToDiseaseAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "ModelToDiseaseAssociationMixin",
      "domain_of": [
        "ModelToDiseaseAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "NamedThing",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "model_to_disease_association_mixin_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "The relationship to the disease",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "ModelToDiseaseAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "ModelToDiseaseAssociationMixin",
      "domain_of": [
        "ModelToDiseaseAssociationMixin"
      ],
      "subproperty_of": "model_of",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_as_a_model_of_disease_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "A gene that has a role in modeling the disease. This may be a model organism ortholog of a known disease gene, or it may be a gene whose mutants recapitulate core features of the disease.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "gene_to_disease_association_subject",
      "domain": "GeneAsAModelOfDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "inlined": true,
      "alias": "subject",
      "owner": "GeneAsAModelOfDiseaseAssociation",
      "domain_of": [
        "GeneAsAModelOfDiseaseAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "variant_as_a_model_of_disease_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "A variant that has a role in modeling the disease.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "variant_to_disease_association_subject",
      "domain": "VariantAsAModelOfDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "VariantAsAModelOfDiseaseAssociation",
      "domain_of": [
        "VariantAsAModelOfDiseaseAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "SequenceVariant",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genotype_as_a_model_of_disease_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "A genotype that has a role in modeling the disease.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "genotype_to_disease_association_subject",
      "domain": "GenotypeAsAModelOfDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "GenotypeAsAModelOfDiseaseAssociation",
      "domain_of": [
        "GenotypeAsAModelOfDiseaseAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Genotype",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "cell_line_as_a_model_of_disease_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "A cell line derived from an organismal entity with a disease state that is used as a model of that disease.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "cell_line_to_disease_or_phenotypic_feature_association_subject",
      "domain": "CellLineAsAModelOfDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "CellLineAsAModelOfDiseaseAssociation",
      "domain_of": [
        "CellLineAsAModelOfDiseaseAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "CellLine",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organismal_entity_as_a_model_of_disease_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "A organismal entity (strain, breed) with a predisposition to a disease, or bred/created specifically to model a disease.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "OrganismalEntityAsAModelOfDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "OrganismalEntityAsAModelOfDiseaseAssociation",
      "domain_of": [
        "OrganismalEntityAsAModelOfDiseaseAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "OrganismalEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_has_variant_that_contributes_to_disease_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "A gene that has a role in modeling the disease. This may be a model organism ortholog of a known disease gene, or it may be a gene whose mutants recapitulate core features of the disease.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "gene_to_disease_association_subject",
      "domain": "GeneHasVariantThatContributesToDiseaseAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "inlined": true,
      "alias": "subject",
      "owner": "GeneHasVariantThatContributesToDiseaseAssociation",
      "domain_of": [
        "GeneHasVariantThatContributesToDiseaseAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_expression_site_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "gene in which variation is correlated with the phenotypic feature",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GeneToExpressionSiteAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "inlined": true,
      "alias": "subject",
      "owner": "GeneToExpressionSiteAssociation",
      "domain_of": [
        "GeneToExpressionSiteAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_expression_site_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "location in which the gene is expressed",
      "examples": [
        {
          "value": "UBERON:0002037",
          "description": "cerebellum",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "GeneToExpressionSiteAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "GeneToExpressionSiteAssociation",
      "domain_of": [
        "GeneToExpressionSiteAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "AnatomicalEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_expression_site_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "expression relationship",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "GeneToExpressionSiteAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "GeneToExpressionSiteAssociation",
      "domain_of": [
        "GeneToExpressionSiteAssociation"
      ],
      "subproperty_of": "expressed_in",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_expression_site_association_stage_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/stage_qualifier",
      "description": "stage at which the gene is expressed in the site",
      "examples": [
        {
          "value": "UBERON:0000069",
          "description": "larval stage",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "stage_qualifier",
      "domain": "GeneToExpressionSiteAssociation",
      "slot_uri": "https://w3id.org/biolink/vocab/stage_qualifier",
      "alias": "stage qualifier",
      "owner": "GeneToExpressionSiteAssociation",
      "domain_of": [
        "GeneToExpressionSiteAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "stage qualifier",
      "range": "LifeStage",
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_expression_site_association_quantifier_qualifier",
      "definition_uri": "https://w3id.org/biolink/vocab/quantifier_qualifier",
      "narrow_mappings": [
        "http://loinc.org/rdf/analyzes",
        "http://loinc.org/rdf/measured_by",
        "http://loinc.org/rdf/property_of",
        "https://skr3.nlm.nih.gov/SemMedDBmeasures",
        "http://identifiers.org/umls/measures"
      ],
      "description": "can be used to indicate magnitude, or also ranking",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "quantifier_qualifier",
      "domain": "GeneToExpressionSiteAssociation",
      "slot_uri": "https://w3id.org/biolink/vocab/quantifier_qualifier",
      "inlined": true,
      "alias": "quantifier qualifier",
      "owner": "GeneToExpressionSiteAssociation",
      "domain_of": [
        "GeneToExpressionSiteAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "quantifier qualifier",
      "range": "OntologyClass",
      "@type": "SlotDefinition"
    },
    {
      "name": "sequence_variant_modulates_treatment_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "variant that modulates the treatment of some disease",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "SequenceVariantModulatesTreatmentAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "SequenceVariantModulatesTreatmentAssociation",
      "domain_of": [
        "SequenceVariantModulatesTreatmentAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "SequenceVariant",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "sequence_variant_modulates_treatment_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "treatment whose efficacy is modulated by the subject variant",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "SequenceVariantModulatesTreatmentAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "SequenceVariantModulatesTreatmentAssociation",
      "domain_of": [
        "SequenceVariantModulatesTreatmentAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "Treatment",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "functional_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "gene, product or macromolecular complex mixin that has the function associated with the GO term",
      "examples": [
        {
          "value": "ZFIN:ZDB-GENE-050417-357",
          "description": "twist1b",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "FunctionalAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "inlined": true,
      "alias": "subject",
      "owner": "FunctionalAssociation",
      "domain_of": [
        "FunctionalAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "MacromolecularMachineMixin",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "functional_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "class describing the activity, process or localization of the gene product",
      "examples": [
        {
          "value": "GO:0016301",
          "description": "kinase activity",
          "@type": "Example"
        },
        {
          "value": "GO:0045211",
          "description": "postsynaptic membrane",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "values_from": [
        "go"
      ],
      "domain": "FunctionalAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "inlined": true,
      "alias": "object",
      "owner": "FunctionalAssociation",
      "domain_of": [
        "FunctionalAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "GeneOntologyClass",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "macromolecular_machine_to_entity_association_mixin_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "MacromolecularMachineToEntityAssociationMixin",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "MacromolecularMachineToEntityAssociationMixin",
      "domain_of": [
        "MacromolecularMachineToEntityAssociationMixin"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "NamedThing",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "macromolecular_machine_to_molecular_activity_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "functional_association_object",
      "domain": "MacromolecularMachineToMolecularActivityAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "MacromolecularMachineToMolecularActivityAssociation",
      "domain_of": [
        "MacromolecularMachineToMolecularActivityAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "MolecularActivity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "macromolecular_machine_to_biological_process_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "functional_association_object",
      "domain": "MacromolecularMachineToBiologicalProcessAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "MacromolecularMachineToBiologicalProcessAssociation",
      "domain_of": [
        "MacromolecularMachineToBiologicalProcessAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "BiologicalProcess",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "macromolecular_machine_to_cellular_component_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "functional_association_object",
      "domain": "MacromolecularMachineToCellularComponentAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "MacromolecularMachineToCellularComponentAssociation",
      "domain_of": [
        "MacromolecularMachineToCellularComponentAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "CellularComponent",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_go_term_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "gene, product or macromolecular complex that has the function associated with the GO term",
      "examples": [
        {
          "value": "ZFIN:ZDB-GENE-050417-357",
          "description": "twist1b",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "functional_association_subject",
      "domain": "GeneToGoTermAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "GeneToGoTermAssociation",
      "domain_of": [
        "GeneToGoTermAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "MolecularEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_go_term_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "class describing the activity, process or localization of the gene product",
      "examples": [
        {
          "value": "GO:0016301",
          "description": "kinase activity",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "functional_association_object",
      "values_from": [
        "go"
      ],
      "domain": "GeneToGoTermAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "inlined": true,
      "alias": "object",
      "owner": "GeneToGoTermAssociation",
      "domain_of": [
        "GeneToGoTermAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "GeneOntologyClass",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genomic_sequence_localization_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "aliases": [
        "sequence feature"
      ],
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GenomicSequenceLocalization",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "GenomicSequenceLocalization",
      "domain_of": [
        "GenomicSequenceLocalization"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "GenomicEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genomic_sequence_localization_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "aliases": [
        "reference"
      ],
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "GenomicSequenceLocalization",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "GenomicSequenceLocalization",
      "domain_of": [
        "GenomicSequenceLocalization"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "GenomicEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "genomic_sequence_localization_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "GenomicSequenceLocalization",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "GenomicSequenceLocalization",
      "domain_of": [
        "GenomicSequenceLocalization"
      ],
      "subproperty_of": "has_sequence_location",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "sequence_feature_relationship_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "SequenceFeatureRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "SequenceFeatureRelationship",
      "domain_of": [
        "SequenceFeatureRelationship"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "GenomicEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "sequence_feature_relationship_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "SequenceFeatureRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "SequenceFeatureRelationship",
      "domain_of": [
        "SequenceFeatureRelationship"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "GenomicEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "transcript_to_gene_relationship_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "sequence_feature_relationship_subject",
      "domain": "TranscriptToGeneRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "TranscriptToGeneRelationship",
      "domain_of": [
        "TranscriptToGeneRelationship"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Transcript",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "transcript_to_gene_relationship_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "sequence_feature_relationship_object",
      "domain": "TranscriptToGeneRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "TranscriptToGeneRelationship",
      "domain_of": [
        "TranscriptToGeneRelationship"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "Gene",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_gene_product_relationship_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "sequence_feature_relationship_subject",
      "domain": "GeneToGeneProductRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "GeneToGeneProductRelationship",
      "domain_of": [
        "GeneToGeneProductRelationship"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Gene",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_gene_product_relationship_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "sequence_feature_relationship_object",
      "domain": "GeneToGeneProductRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "inlined": true,
      "alias": "object",
      "owner": "GeneToGeneProductRelationship",
      "domain_of": [
        "GeneToGeneProductRelationship"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "GeneProductMixin",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_to_gene_product_relationship_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "GeneToGeneProductRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "GeneToGeneProductRelationship",
      "domain_of": [
        "GeneToGeneProductRelationship"
      ],
      "subproperty_of": "has_gene_product",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "exon_to_transcript_relationship_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "sequence_feature_relationship_subject",
      "domain": "ExonToTranscriptRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "ExonToTranscriptRelationship",
      "domain_of": [
        "ExonToTranscriptRelationship"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "Exon",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "exon_to_transcript_relationship_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "sequence_feature_relationship_object",
      "domain": "ExonToTranscriptRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "ExonToTranscriptRelationship",
      "domain_of": [
        "ExonToTranscriptRelationship"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "Transcript",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_regulatory_relationship_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "the direction is always from regulator to regulated",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "GeneRegulatoryRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "GeneRegulatoryRelationship",
      "domain_of": [
        "GeneRegulatoryRelationship"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_regulatory_relationship_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "GeneRegulatoryRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "inlined": true,
      "alias": "subject",
      "owner": "GeneRegulatoryRelationship",
      "domain_of": [
        "GeneRegulatoryRelationship"
      ],
      "role": "regulatory gene",
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "gene_regulatory_relationship_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "GeneRegulatoryRelationship",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "inlined": true,
      "alias": "object",
      "owner": "GeneRegulatoryRelationship",
      "domain_of": [
        "GeneRegulatoryRelationship"
      ],
      "role": "regulated gene",
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "GeneOrGeneProduct",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "anatomical_entity_to_anatomical_entity_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "AnatomicalEntityToAnatomicalEntityAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "AnatomicalEntityToAnatomicalEntityAssociation",
      "domain_of": [
        "AnatomicalEntityToAnatomicalEntityAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "AnatomicalEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "anatomical_entity_to_anatomical_entity_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "AnatomicalEntityToAnatomicalEntityAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "AnatomicalEntityToAnatomicalEntityAssociation",
      "domain_of": [
        "AnatomicalEntityToAnatomicalEntityAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "AnatomicalEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "anatomical_entity_to_anatomical_entity_part_of_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the part",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "anatomical_entity_to_anatomical_entity_association_subject",
      "domain": "AnatomicalEntityToAnatomicalEntityPartOfAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "AnatomicalEntityToAnatomicalEntityPartOfAssociation",
      "domain_of": [
        "AnatomicalEntityToAnatomicalEntityPartOfAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "AnatomicalEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "anatomical_entity_to_anatomical_entity_part_of_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the whole",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "anatomical_entity_to_anatomical_entity_association_object",
      "domain": "AnatomicalEntityToAnatomicalEntityPartOfAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "AnatomicalEntityToAnatomicalEntityPartOfAssociation",
      "domain_of": [
        "AnatomicalEntityToAnatomicalEntityPartOfAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "AnatomicalEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "anatomical_entity_to_anatomical_entity_part_of_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "AnatomicalEntityToAnatomicalEntityPartOfAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "AnatomicalEntityToAnatomicalEntityPartOfAssociation",
      "domain_of": [
        "AnatomicalEntityToAnatomicalEntityPartOfAssociation"
      ],
      "subproperty_of": "part_of",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "anatomical_entity_to_anatomical_entity_ontogenic_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the structure at a later time",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "anatomical_entity_to_anatomical_entity_association_subject",
      "domain": "AnatomicalEntityToAnatomicalEntityOntogenicAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "AnatomicalEntityToAnatomicalEntityOntogenicAssociation",
      "domain_of": [
        "AnatomicalEntityToAnatomicalEntityOntogenicAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "AnatomicalEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "anatomical_entity_to_anatomical_entity_ontogenic_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the structure at an earlier time",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "anatomical_entity_to_anatomical_entity_association_object",
      "domain": "AnatomicalEntityToAnatomicalEntityOntogenicAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "AnatomicalEntityToAnatomicalEntityOntogenicAssociation",
      "domain_of": [
        "AnatomicalEntityToAnatomicalEntityOntogenicAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "AnatomicalEntity",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "anatomical_entity_to_anatomical_entity_ontogenic_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "AnatomicalEntityToAnatomicalEntityOntogenicAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "AnatomicalEntityToAnatomicalEntityOntogenicAssociation",
      "domain_of": [
        "AnatomicalEntityToAnatomicalEntityOntogenicAssociation"
      ],
      "subproperty_of": "develops_from",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_entity_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "organism taxon that is the subject of the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "OrganismTaxonToEntityAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "OrganismTaxonToEntityAssociation",
      "domain_of": [
        "OrganismTaxonToEntityAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "OrganismTaxon",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_organism_taxon_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "OrganismTaxonToOrganismTaxonAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "OrganismTaxonToOrganismTaxonAssociation",
      "domain_of": [
        "OrganismTaxonToOrganismTaxonAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "OrganismTaxon",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_organism_taxon_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "OrganismTaxonToOrganismTaxonAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "OrganismTaxonToOrganismTaxonAssociation",
      "domain_of": [
        "OrganismTaxonToOrganismTaxonAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "OrganismTaxon",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_organism_taxon_specialization_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the more specific taxon",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "organism_taxon_to_organism_taxon_association_subject",
      "domain": "OrganismTaxonToOrganismTaxonSpecialization",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "OrganismTaxonToOrganismTaxonSpecialization",
      "domain_of": [
        "OrganismTaxonToOrganismTaxonSpecialization"
      ],
      "role": "child taxon",
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "OrganismTaxon",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_organism_taxon_specialization_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the more general taxon",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "organism_taxon_to_organism_taxon_association_object",
      "domain": "OrganismTaxonToOrganismTaxonSpecialization",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "OrganismTaxonToOrganismTaxonSpecialization",
      "domain_of": [
        "OrganismTaxonToOrganismTaxonSpecialization"
      ],
      "role": "parent taxon",
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "OrganismTaxon",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_organism_taxon_specialization_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "OrganismTaxonToOrganismTaxonSpecialization",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "OrganismTaxonToOrganismTaxonSpecialization",
      "domain_of": [
        "OrganismTaxonToOrganismTaxonSpecialization"
      ],
      "subproperty_of": "subclass_of",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_organism_taxon_interaction_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the taxon that is the subject of the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "organism_taxon_to_organism_taxon_association_subject",
      "domain": "OrganismTaxonToOrganismTaxonInteraction",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "OrganismTaxonToOrganismTaxonInteraction",
      "domain_of": [
        "OrganismTaxonToOrganismTaxonInteraction"
      ],
      "role": "interactor taxon",
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "OrganismTaxon",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_organism_taxon_interaction_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the taxon that is the subject of the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "organism_taxon_to_organism_taxon_association_object",
      "domain": "OrganismTaxonToOrganismTaxonInteraction",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "OrganismTaxonToOrganismTaxonInteraction",
      "domain_of": [
        "OrganismTaxonToOrganismTaxonInteraction"
      ],
      "role": "interactee taxon",
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "OrganismTaxon",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_organism_taxon_interaction_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "OrganismTaxonToOrganismTaxonInteraction",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "OrganismTaxonToOrganismTaxonInteraction",
      "domain_of": [
        "OrganismTaxonToOrganismTaxonInteraction"
      ],
      "subproperty_of": "interacts_with",
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_organism_taxon_interaction_associated_environmental_context",
      "definition_uri": "https://w3id.org/biolink/vocab/associated_environmental_context",
      "description": "the environment in which the two taxa interact",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "associated_environmental_context",
      "domain": "OrganismTaxonToOrganismTaxonInteraction",
      "slot_uri": "https://w3id.org/biolink/vocab/associated_environmental_context",
      "alias": "associated environmental context",
      "owner": "OrganismTaxonToOrganismTaxonInteraction",
      "domain_of": [
        "OrganismTaxonToOrganismTaxonInteraction"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "associated environmental context",
      "range": "string",
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_environment_association_subject",
      "definition_uri": "https://w3id.org/biolink/vocab/subject",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation subject"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with outgoing relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedSource",
        "http://purl.org/oban/association_has_subject"
      ],
      "description": "the taxon that is the subject of the association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "subject",
      "domain": "OrganismTaxonToEnvironmentAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject",
      "alias": "subject",
      "owner": "OrganismTaxonToEnvironmentAssociation",
      "domain_of": [
        "OrganismTaxonToEnvironmentAssociation"
      ],
      "role": "interactor taxon",
      "is_usage_slot": true,
      "usage_slot_name": "subject",
      "range": "OrganismTaxon",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_environment_association_object",
      "definition_uri": "https://w3id.org/biolink/vocab/object",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "descriptor"
        },
        "neo4j": {
          "local_name_source": "neo4j",
          "local_name_value": "node with incoming relationship"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#object"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedTarget",
        "http://purl.org/oban/association_has_object"
      ],
      "description": "the environment in which the organism occurs",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "object",
      "domain": "OrganismTaxonToEnvironmentAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#object",
      "alias": "object",
      "owner": "OrganismTaxonToEnvironmentAssociation",
      "domain_of": [
        "OrganismTaxonToEnvironmentAssociation"
      ],
      "role": "environmental context",
      "is_usage_slot": true,
      "usage_slot_name": "object",
      "range": "NamedThing",
      "required": true,
      "@type": "SlotDefinition"
    },
    {
      "name": "organism_taxon_to_environment_association_predicate",
      "definition_uri": "https://w3id.org/biolink/vocab/predicate",
      "local_names": {
        "ga4gh": {
          "local_name_source": "ga4gh",
          "local_name_value": "annotation predicate"
        },
        "translator": {
          "local_name_source": "translator",
          "local_name_value": "predicate"
        }
      },
      "mappings": [
        "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate"
      ],
      "exact_mappings": [
        "http://www.w3.org/2002/07/owl#annotatedProperty",
        "http://purl.org/oban/association_has_predicate"
      ],
      "description": "predicate describing the relationship between the taxon and the environment\n ",
      "notes": [
        "Has a value from the Biolink related_to hierarchy. In RDF,  this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "predicate",
      "domain": "OrganismTaxonToEnvironmentAssociation",
      "slot_uri": "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate",
      "alias": "predicate",
      "owner": "OrganismTaxonToEnvironmentAssociation",
      "domain_of": [
        "OrganismTaxonToEnvironmentAssociation"
      ],
      "is_usage_slot": true,
      "usage_slot_name": "predicate",
      "range": "predicate_type",
      "required": true,
      "@type": "SlotDefinition"
    }
  ],
  "classes": [
    {
      "name": "OntologyClass",
      "id_prefixes": [
        "MESH",
        "UMLS",
        "KEGG.BRITE"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/OntologyClass",
      "exact_mappings": [
        "owl:Class",
        "schema:Class"
      ],
      "description": "a concept or class in an ontology, vocabulary or thesaurus. Note that nodes in a biolink compatible KG can be considered both instances of biolink classes, and OWL classes in their own right. In general you should not need to use this class directly. Instead, use the appropriate biolink class. For example, for the GO concept of endocytosis (GO:0006897), use bl:BiologicalProcess as the type.",
      "comments": [
        "This is modeled as a mixin. 'ontology class' should not be the primary type of a node in the KG. Instead you should use an informative bioloink category, such as AnatomicalEntity (for Uberon classes), ChemicalSubstance (for CHEBI or CHEMBL), etc",
        "Note that formally this is a metaclass. Instances of this class are instances in the graph, but can be the object of 'type' edges. For example, if we had a node in the graph representing a specific brain of a specific patient (e.g brain001), this could have  a category of bl:Sample, and by typed more specifically with an ontology class UBERON:nnn, which has as category bl:AnatomicalEntity"
      ],
      "examples": [
        {
          "value": "UBERON:0000955",
          "description": "the class 'brain' from the Uberon anatomy ontology",
          "@type": "Example"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "see_also": [
        "https://github.com/biolink/biolink-model/issues/486"
      ],
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/OntologyClass",
      "@type": "ClassDefinition"
    },
    {
      "name": "Annotation",
      "definition_uri": "https://w3id.org/biolink/vocab/Annotation",
      "description": "Biolink Model root class for entity annotations.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "abstract": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Annotation",
      "@type": "ClassDefinition"
    },
    {
      "name": "QuantityValue",
      "definition_uri": "https://w3id.org/biolink/vocab/QuantityValue",
      "description": "A value of an attribute that is quantitative and measurable, expressed as a combination of a unit and a numeric value",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Annotation",
      "slots": [
        "has_unit",
        "has_numeric_value"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/QuantityValue",
      "@type": "ClassDefinition"
    },
    {
      "name": "Attribute",
      "id_prefixes": [
        "EDAM-DATA",
        "EDAM-FORMAT",
        "EDAM-OPERATION",
        "EDAM-TOPIC"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Attribute",
      "exact_mappings": [
        "SIO:000614"
      ],
      "description": "A property or characteristic of an entity. For example, an apple may have properties such as color, shape, age, crispiness. An environmental sample may have attributes such as depth, lat, long, material.",
      "in_subset": [
        "samples"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Annotation",
      "mixins": [
        "OntologyClass"
      ],
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Attribute",
      "@type": "ClassDefinition"
    },
    {
      "name": "BiologicalSex",
      "definition_uri": "https://w3id.org/biolink/vocab/BiologicalSex",
      "exact_mappings": [
        "PATO:0000047"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Attribute",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/BiologicalSex",
      "@type": "ClassDefinition"
    },
    {
      "name": "PhenotypicSex",
      "definition_uri": "https://w3id.org/biolink/vocab/PhenotypicSex",
      "exact_mappings": [
        "PATO:0001894"
      ],
      "description": "An attribute corresponding to the phenotypic sex of the individual, based upon the reproductive organs present.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalSex",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PhenotypicSex",
      "@type": "ClassDefinition"
    },
    {
      "name": "GenotypicSex",
      "definition_uri": "https://w3id.org/biolink/vocab/GenotypicSex",
      "exact_mappings": [
        "PATO:0020000"
      ],
      "description": "An attribute corresponding to the genotypic sex of the individual, based upon genotypic composition of sex chromosomes.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalSex",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GenotypicSex",
      "@type": "ClassDefinition"
    },
    {
      "name": "SeverityValue",
      "definition_uri": "https://w3id.org/biolink/vocab/SeverityValue",
      "description": "describes the severity of a phenotypic feature or disease",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Attribute",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/SeverityValue",
      "@type": "ClassDefinition"
    },
    {
      "name": "RelationshipQuantifier",
      "definition_uri": "https://w3id.org/biolink/vocab/RelationshipQuantifier",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/RelationshipQuantifier",
      "@type": "ClassDefinition"
    },
    {
      "name": "SensitivityQuantifier",
      "definition_uri": "https://w3id.org/biolink/vocab/SensitivityQuantifier",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "RelationshipQuantifier",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/SensitivityQuantifier",
      "@type": "ClassDefinition"
    },
    {
      "name": "SpecificityQuantifier",
      "definition_uri": "https://w3id.org/biolink/vocab/SpecificityQuantifier",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "RelationshipQuantifier",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/SpecificityQuantifier",
      "@type": "ClassDefinition"
    },
    {
      "name": "PathognomonicityQuantifier",
      "definition_uri": "https://w3id.org/biolink/vocab/PathognomonicityQuantifier",
      "description": "A relationship quantifier between a variant or symptom and a disease, which is high when the presence of the feature implies the existence of the disease",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "SpecificityQuantifier",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PathognomonicityQuantifier",
      "@type": "ClassDefinition"
    },
    {
      "name": "FrequencyQuantifier",
      "definition_uri": "https://w3id.org/biolink/vocab/FrequencyQuantifier",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "RelationshipQuantifier",
      "mixin": true,
      "slots": [
        "has_count",
        "has_total",
        "has_quotient",
        "has_percentage"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/FrequencyQuantifier",
      "@type": "ClassDefinition"
    },
    {
      "name": "ChemicalOrDrugOrTreatment",
      "definition_uri": "https://w3id.org/biolink/vocab/ChemicalOrDrugOrTreatment",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ChemicalOrDrugOrTreatment",
      "@type": "ClassDefinition"
    },
    {
      "name": "Entity",
      "definition_uri": "https://w3id.org/biolink/vocab/Entity",
      "description": "Root Biolink Model class for all things and informational relationships, real or imagined.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "abstract": true,
      "slots": [
        "id",
        "iri",
        "category",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Entity",
      "@type": "ClassDefinition"
    },
    {
      "name": "NamedThing",
      "definition_uri": "https://w3id.org/biolink/vocab/NamedThing",
      "exact_mappings": [
        "BFO:0000001",
        "WIKIDATA:Q35120",
        "UMLSSG:OBJC",
        "UMLSSC:T071",
        "UMLSST:enty"
      ],
      "description": "a databased entity or concept/class",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Entity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/NamedThing",
      "@type": "ClassDefinition"
    },
    {
      "name": "RelationshipType",
      "definition_uri": "https://w3id.org/biolink/vocab/RelationshipType",
      "description": "An OWL property used as an edge label",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OntologyClass",
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/RelationshipType",
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneOntologyClass",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneOntologyClass",
      "description": "an ontology class that describes a functional aspect of a gene, gene prodoct or complex",
      "in_subset": [
        "testing"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OntologyClass",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeneOntologyClass",
      "@type": "ClassDefinition"
    },
    {
      "name": "UnclassifiedOntologyClass",
      "definition_uri": "https://w3id.org/biolink/vocab/UnclassifiedOntologyClass",
      "description": "this is used for nodes that are taken from an ontology but are not typed using an existing biolink class",
      "in_subset": [
        "testing"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OntologyClass",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/UnclassifiedOntologyClass",
      "@type": "ClassDefinition"
    },
    {
      "name": "TaxonomicRank",
      "id_prefixes": [
        "TAXRANK"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/TaxonomicRank",
      "mappings": [
        "WIKIDATA:Q427626"
      ],
      "description": "A descriptor for the rank within a taxonomic classification. Example instance: TAXRANK:0000017 (kingdom)",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OntologyClass",
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/TaxonomicRank",
      "@type": "ClassDefinition"
    },
    {
      "name": "OrganismTaxon",
      "id_prefixes": [
        "NCBITaxon",
        "MESH"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/OrganismTaxon",
      "aliases": [
        "taxon",
        "taxonomic classification"
      ],
      "exact_mappings": [
        "WIKIDATA:Q16521"
      ],
      "narrow_mappings": [
        "UMLSSC:T005",
        "UMLSST:virs",
        "UMLSSC:T007",
        "UMLSST:bact",
        "UMLSSC:T194",
        "UMLSST:arch",
        "UMLSSC:T204",
        "UMLSST:euka",
        "UMLSSC:T002",
        "UMLSST:plnt",
        "UMLSSC:T004",
        "UMLSST:fngs",
        "UMLSSC:T008",
        "UMLSST:anim",
        "UMLSSC:T010",
        "UMLSST:vtbt",
        "UMLSSC:T011",
        "UMLSST:amph",
        "UMLSSC:T012",
        "UMLSST:bird",
        "UMLSSC:T013",
        "UMLSST:fish",
        "UMLSSC:T014",
        "UMLSST:rept",
        "UMLSSC:T015",
        "UMLSST:mamm",
        "UMLSSC:T016",
        "UMLSST:humn"
      ],
      "description": "A classification of a set of organisms. Example instances: NCBITaxon:9606 (Homo sapiens), NCBITaxon:2 (Bacteria). Can also be used to represent strains or subspecies.",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "values_from": [
        "NCBITaxon"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "organism_taxon_has_taxonomic_rank",
        "organism_taxon_subclass_of"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/OrganismTaxon",
      "@type": "ClassDefinition"
    },
    {
      "name": "AdministrativeEntity",
      "definition_uri": "https://w3id.org/biolink/vocab/AdministrativeEntity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "abstract": true,
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/AdministrativeEntity",
      "@type": "ClassDefinition"
    },
    {
      "name": "Agent",
      "id_prefixes": [
        "isbn",
        "ORCID",
        "ScopusID",
        "ResearchID",
        "GSID",
        "isni"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Agent",
      "aliases": [
        "group"
      ],
      "exact_mappings": [
        "prov:Agent",
        "dct:Agent"
      ],
      "narrow_mappings": [
        "UMLSSG:ORGA",
        "UMLSSC:T092",
        "UMLSST:orgt",
        "UMLSSC:T093",
        "UMLSST:hcro",
        "UMLSSC:T094",
        "UMLSST:pros",
        "UMLSSC:T095",
        "UMLSST:shro",
        "UMLSSC:T096",
        "UMLSST:grup",
        "UMLSSC:T097",
        "UMLSST:prog"
      ],
      "description": "person, group, organization or project that provides a piece of information (i.e. a knowledge association)",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "AdministrativeEntity",
      "slots": [
        "iri",
        "type",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "affiliation",
        "address",
        "agent_id",
        "agent_name"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Agent",
      "@type": "ClassDefinition"
    },
    {
      "name": "InformationContentEntity",
      "id_prefixes": [
        "doi"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/InformationContentEntity",
      "aliases": [
        "information",
        "information artefact",
        "information entity"
      ],
      "exact_mappings": [
        "IAO:0000030"
      ],
      "narrow_mappings": [
        "UMLSSG:CONC",
        "UMLSSC:T077",
        "UMLSST:cnce",
        "UMLSSC:T078",
        "UMLSST:idcn",
        "UMLSSC:T079",
        "UMLSST:tmco",
        "UMLSSC:T080",
        "UMLSST:qlco",
        "UMLSSC:T081",
        "UMLSST:qnco",
        "UMLSSC:T082",
        "UMLSST:spco",
        "UMLSSC:T089",
        "UMLSST:rnlw",
        "UMLSSC:T102",
        "UMLSST:grpa",
        "UMLSSC:T169",
        "UMLSST:ftcn",
        "UMLSSC:T171",
        "UMLSST:lang",
        "UMLSSC:T185",
        "UMLSST:clas"
      ],
      "description": "a piece of information that typically describes some topic of discourse or is used as support.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "abstract": true,
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/InformationContentEntity",
      "@type": "ClassDefinition"
    },
    {
      "name": "Dataset",
      "definition_uri": "https://w3id.org/biolink/vocab/Dataset",
      "exact_mappings": [
        "IAO:0000100",
        "dctypes:Dataset",
        "schema:dataset"
      ],
      "description": "an item that refers to a collection of data from a data source.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "InformationContentEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Dataset",
      "@type": "ClassDefinition"
    },
    {
      "name": "DatasetDistribution",
      "definition_uri": "https://w3id.org/biolink/vocab/DatasetDistribution",
      "exact_mappings": [
        "dcat:Distribution"
      ],
      "description": "an item that holds distribution level information about a dataset.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "InformationContentEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date",
        "distribution_download_url"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DatasetDistribution",
      "@type": "ClassDefinition"
    },
    {
      "name": "DatasetVersion",
      "definition_uri": "https://w3id.org/biolink/vocab/DatasetVersion",
      "description": "an item that holds version level information about a dataset.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "InformationContentEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date",
        "has_dataset",
        "ingest_date",
        "has_distribution"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DatasetVersion",
      "@type": "ClassDefinition"
    },
    {
      "name": "DatasetSummary",
      "definition_uri": "https://w3id.org/biolink/vocab/DatasetSummary",
      "description": "an item that holds summary level information about a dataset.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "InformationContentEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date",
        "source_web_page",
        "source_logo"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DatasetSummary",
      "@type": "ClassDefinition"
    },
    {
      "name": "ConfidenceLevel",
      "definition_uri": "https://w3id.org/biolink/vocab/ConfidenceLevel",
      "exact_mappings": [
        "CIO:0000028",
        "SEPIO:0000187"
      ],
      "close_mappings": [
        "SEPIO:0000167"
      ],
      "description": "Level of confidence in a statement",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "InformationContentEntity",
      "values_from": [
        "cio"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ConfidenceLevel",
      "@type": "ClassDefinition"
    },
    {
      "name": "EvidenceType",
      "definition_uri": "https://w3id.org/biolink/vocab/EvidenceType",
      "aliases": [
        "evidence code"
      ],
      "exact_mappings": [
        "ECO:0000000"
      ],
      "description": "Class of evidence that supports an association",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "InformationContentEntity",
      "values_from": [
        "eco"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/EvidenceType",
      "@type": "ClassDefinition"
    },
    {
      "name": "Publication",
      "id_prefixes": [
        "NLMID"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Publication",
      "exact_mappings": [
        "IAO:0000311"
      ],
      "narrow_mappings": [
        "IAO:0000013",
        "UMLSSC:T170",
        "UMLSST:inpr"
      ],
      "description": "Any published piece of information. Can refer to a whole publication, its encompassing publication (i.e. journal or book) or to a part of a publication, if of significant knowledge scope (e.g. a figure, figure legend, or section highlighted by NLP). The scope is intended to be general and include information published on the web, as well as printed materials, either directly or in one of the Publication Biolink category subclasses.",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "InformationContentEntity",
      "slots": [
        "iri",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date",
        "authors",
        "publication_pages",
        "summary",
        "keywords",
        "mesh_terms",
        "xref",
        "publication_id",
        "publication_name",
        "publication_type"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Publication",
      "@type": "ClassDefinition"
    },
    {
      "name": "Book",
      "id_prefixes": [
        "isbn",
        "NLMID"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Book",
      "description": "This class may rarely be instantiated except if use cases of a given knowledge graph support its utility.",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Publication",
      "slots": [
        "iri",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date",
        "authors",
        "publication_pages",
        "summary",
        "keywords",
        "mesh_terms",
        "xref",
        "publication_name",
        "book_id",
        "book_type"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Book",
      "@type": "ClassDefinition"
    },
    {
      "name": "BookChapter",
      "definition_uri": "https://w3id.org/biolink/vocab/BookChapter",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Publication",
      "slots": [
        "iri",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date",
        "authors",
        "publication_pages",
        "summary",
        "keywords",
        "mesh_terms",
        "xref",
        "publication_id",
        "publication_name",
        "publication_type",
        "book_chapter_published_in",
        "volume",
        "chapter"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/BookChapter",
      "@type": "ClassDefinition"
    },
    {
      "name": "Serial",
      "id_prefixes": [
        "issn",
        "NLMID"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Serial",
      "aliases": [
        "journal"
      ],
      "description": "This class may rarely be instantiated except if use cases of a given knowledge graph support its utility.",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Publication",
      "slots": [
        "iri",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date",
        "authors",
        "publication_pages",
        "summary",
        "keywords",
        "mesh_terms",
        "xref",
        "publication_name",
        "iso_abbreviation",
        "volume",
        "issue",
        "serial_id",
        "serial_type"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Serial",
      "@type": "ClassDefinition"
    },
    {
      "name": "Article",
      "id_prefixes": [
        "PMID"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Article",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Publication",
      "slots": [
        "iri",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "license",
        "rights",
        "format",
        "creation_date",
        "authors",
        "publication_pages",
        "summary",
        "keywords",
        "mesh_terms",
        "xref",
        "publication_id",
        "publication_name",
        "publication_type",
        "article_published_in",
        "article_iso_abbreviation",
        "volume",
        "issue"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Article",
      "@type": "ClassDefinition"
    },
    {
      "name": "PhysicalEssenceOrOccurrent",
      "definition_uri": "https://w3id.org/biolink/vocab/PhysicalEssenceOrOccurrent",
      "description": "Either a physical or processual entity.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PhysicalEssenceOrOccurrent",
      "@type": "ClassDefinition"
    },
    {
      "name": "PhysicalEssence",
      "definition_uri": "https://w3id.org/biolink/vocab/PhysicalEssence",
      "description": "Semantic mixin concept.  Pertains to entities that have physical properties such as mass, volume, or charge.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PhysicalEssenceOrOccurrent",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PhysicalEssence",
      "@type": "ClassDefinition"
    },
    {
      "name": "PhysicalEntity",
      "definition_uri": "https://w3id.org/biolink/vocab/PhysicalEntity",
      "exact_mappings": [
        "UMLSSC:T072",
        "UMLSST:phob"
      ],
      "narrow_mappings": [
        "UMLSSC:T073",
        "UMLSST:mnob"
      ],
      "description": "An entity that has material reality (a.k.a. physical essence).",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "mixins": [
        "PhysicalEssence"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PhysicalEntity",
      "@type": "ClassDefinition"
    },
    {
      "name": "Occurrent",
      "definition_uri": "https://w3id.org/biolink/vocab/Occurrent",
      "exact_mappings": [
        "BFO:0000003"
      ],
      "description": "A processual entity.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PhysicalEssenceOrOccurrent",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Occurrent",
      "@type": "ClassDefinition"
    },
    {
      "name": "ActivityAndBehavior",
      "definition_uri": "https://w3id.org/biolink/vocab/ActivityAndBehavior",
      "exact_mappings": [
        "UMLSSG:ACTI"
      ],
      "description": "Activity or behavior of any independent integral living, organization or mechanical actor in the world",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Occurrent",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ActivityAndBehavior",
      "@type": "ClassDefinition"
    },
    {
      "name": "Activity",
      "definition_uri": "https://w3id.org/biolink/vocab/Activity",
      "exact_mappings": [
        "prov:Activity",
        "NCIT:C43431",
        "UMLSSC:T052",
        "UMLSST:acty"
      ],
      "narrow_mappings": [
        "UMLSSC:T056",
        "UMLSST:dora",
        "UMLSSC:T057",
        "UMLSST:ocac",
        "UMLSSC:T064",
        "UMLSST:gora",
        "UMLSSC:T066",
        "UMLSST:mcha",
        "UMLSSC:T062",
        "UMLSST:resa",
        "UMLSSC:T065",
        "UMLSST:edac",
        "UMLSSC:T058",
        "UMLSST:hlca"
      ],
      "description": "An activity is something that occurs over a period of time and acts upon or with entities; it may include consuming, processing, transforming, modifying, relocating, using, or generating entities.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "mixins": [
        "ActivityAndBehavior"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Activity",
      "@type": "ClassDefinition"
    },
    {
      "name": "Procedure",
      "definition_uri": "https://w3id.org/biolink/vocab/Procedure",
      "exact_mappings": [
        "UMLSSG:PROC"
      ],
      "narrow_mappings": [
        "UMLSSC:T059",
        "UMLSST:lbpr",
        "UMLSSC:T060",
        "UMLSST:diap",
        "UMLSSC:T061",
        "UMLSST:topp",
        "UMLSSC:T063",
        "UMLSST:mbrt"
      ],
      "description": "A series of actions conducted in a certain order or manner",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "mixins": [
        "ActivityAndBehavior"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Procedure",
      "@type": "ClassDefinition"
    },
    {
      "name": "Phenomenon",
      "definition_uri": "https://w3id.org/biolink/vocab/Phenomenon",
      "exact_mappings": [
        "UMLSSG:PHEN"
      ],
      "narrow_mappings": [
        "UMLSSC:T034",
        "UMLSST:lbtr",
        "UMLSSC:T038",
        "UMLSST:biof",
        "UMLSSC:T069",
        "UMLSST:eehu"
      ],
      "broad_mappings": [
        "UMLSSC:T067",
        "UMLSST:phpr",
        "UMLSSC:T068",
        "UMLSST:hcpp",
        "UMLSSC:T070",
        "UMLSST:npop"
      ],
      "description": "a fact or situation that is observed to exist or happen, especially one whose cause or explanation is in question",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "mixins": [
        "Occurrent"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Phenomenon",
      "@type": "ClassDefinition"
    },
    {
      "name": "Device",
      "definition_uri": "https://w3id.org/biolink/vocab/Device",
      "narrow_mappings": [
        "UMLSSG:DEVI",
        "UMLSSC:T074",
        "UMLSST:medd",
        "UMLSSC:T075",
        "UMLSST:resd",
        "UMLSSC:T203",
        "UMLSST:drdd"
      ],
      "description": "A thing made or adapted for a particular purpose, especially a piece of mechanical or electronic equipment",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Device",
      "@type": "ClassDefinition"
    },
    {
      "name": "StudyPopulation",
      "definition_uri": "https://w3id.org/biolink/vocab/StudyPopulation",
      "close_mappings": [
        "WIKIDATA:Q7229825"
      ],
      "description": "A group of people banded together or treated as a group as participants in a research study.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PopulationOfIndividualOrganisms",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/StudyPopulation",
      "@type": "ClassDefinition"
    },
    {
      "name": "SubjectOfInvestigation",
      "definition_uri": "https://w3id.org/biolink/vocab/SubjectOfInvestigation",
      "description": "An entity that has the role of being studied in an investigation, study, or experiment",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/SubjectOfInvestigation",
      "@type": "ClassDefinition"
    },
    {
      "name": "MaterialSample",
      "id_prefixes": [
        "BIOSAMPLE",
        "GOLD.META"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/MaterialSample",
      "aliases": [
        "biospecimen",
        "sample",
        "biosample",
        "physical sample"
      ],
      "exact_mappings": [
        "OBI:0000747",
        "SIO:001050"
      ],
      "description": "A sample is a limited quantity of something (e.g. an individual or set of individuals from a population, or a portion of a substance) to be used for testing, analysis, inspection, investigation, demonstration, or trial use. [SIO]",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PhysicalEntity",
      "mixins": [
        "SubjectOfInvestigation"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/MaterialSample",
      "@type": "ClassDefinition"
    },
    {
      "name": "PlanetaryEntity",
      "definition_uri": "https://w3id.org/biolink/vocab/PlanetaryEntity",
      "description": "Any entity or process that exists at the level of the whole planet",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PlanetaryEntity",
      "@type": "ClassDefinition"
    },
    {
      "name": "EnvironmentalProcess",
      "definition_uri": "https://w3id.org/biolink/vocab/EnvironmentalProcess",
      "exact_mappings": [
        "ENVO:02500000"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PlanetaryEntity",
      "mixins": [
        "Occurrent"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/EnvironmentalProcess",
      "@type": "ClassDefinition"
    },
    {
      "name": "EnvironmentalFeature",
      "definition_uri": "https://w3id.org/biolink/vocab/EnvironmentalFeature",
      "exact_mappings": [
        "ENVO:01000254"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PlanetaryEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/EnvironmentalFeature",
      "@type": "ClassDefinition"
    },
    {
      "name": "GeographicLocation",
      "definition_uri": "https://w3id.org/biolink/vocab/GeographicLocation",
      "exact_mappings": [
        "UMLSSG:GEOG",
        "UMLSST:geoa",
        "UMLSSC:T083"
      ],
      "description": "a location that can be described in lat/long coordinates",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PlanetaryEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "latitude",
        "longitude"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeographicLocation",
      "@type": "ClassDefinition"
    },
    {
      "name": "GeographicLocationAtTime",
      "definition_uri": "https://w3id.org/biolink/vocab/GeographicLocationAtTime",
      "description": "a location that can be described in lat/long coordinates, for a particular time",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GeographicLocation",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "latitude",
        "longitude",
        "timepoint"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeographicLocationAtTime",
      "@type": "ClassDefinition"
    },
    {
      "name": "BiologicalEntity",
      "definition_uri": "https://w3id.org/biolink/vocab/BiologicalEntity",
      "narrow_mappings": [
        "WIKIDATA:Q28845870",
        "UMLSSC:T050",
        "UMLSST:emod",
        "SIO:010046"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "abstract": true,
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/BiologicalEntity",
      "@type": "ClassDefinition"
    },
    {
      "name": "ThingWithTaxon",
      "definition_uri": "https://w3id.org/biolink/vocab/ThingWithTaxon",
      "description": "A mixin that can be used on any entity that can be taxonomically classified. This includes individual organisms; genes, their products and other molecular entities; body parts; biological processes",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ThingWithTaxon",
      "@type": "ClassDefinition"
    },
    {
      "name": "MolecularEntity",
      "definition_uri": "https://w3id.org/biolink/vocab/MolecularEntity",
      "aliases": [
        "bioentity"
      ],
      "exact_mappings": [
        "CHEBI:24431"
      ],
      "narrow_mappings": [
        "SIO:010341",
        "WIKIDATA:Q43460564",
        "UMLSSG:CHEM",
        "UMLSSC:T085",
        "UMLSST:mosq",
        "UMLSSC:T123",
        "UMLSST:bacs",
        "UMLSSC:T125",
        "UMLSST:horm",
        "UMLSSC:T126",
        "UMLSST:enzy",
        "UMLSSC:T129",
        "UMLSST:imft",
        "UMLSSC:T192",
        "UMLSST:rcpt"
      ],
      "description": "A gene, gene product, small molecule or macromolecule (including protein complex)\"",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalEntity",
      "mixins": [
        "ThingWithTaxon",
        "PhysicalEssence",
        "OntologyClass"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/MolecularEntity",
      "@type": "ClassDefinition"
    },
    {
      "name": "BiologicalProcessOrActivity",
      "id_prefixes": [
        "GO",
        "REACT"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/BiologicalProcessOrActivity",
      "description": "Either an individual molecular activity, or a collection of causally connected molecular activities in a biological system.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalEntity",
      "mixins": [
        "Occurrent",
        "OntologyClass"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "has_input",
        "has_output",
        "enabled_by"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/BiologicalProcessOrActivity",
      "@type": "ClassDefinition"
    },
    {
      "name": "MolecularActivity",
      "id_prefixes": [
        "GO",
        "REACT",
        "RHEA",
        "MetaCyc",
        "EC",
        "TCDB",
        "KEGG.REACTION",
        "KEGG.RCLASS",
        "KEGG.ENZYME"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/MolecularActivity",
      "aliases": [
        "molecular function",
        "molecular event",
        "reaction"
      ],
      "exact_mappings": [
        "GO:0003674",
        "UMLSSC:T044",
        "UMLSST:moft"
      ],
      "description": "An execution of a molecular function carried out by a gene product or macromolecular complex.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalProcessOrActivity",
      "mixins": [
        "Occurrent",
        "OntologyClass"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "molecular_activity_has_input",
        "molecular_activity_has_output",
        "molecular_activity_enabled_by"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/MolecularActivity",
      "@type": "ClassDefinition"
    },
    {
      "name": "BiologicalProcess",
      "id_prefixes": [
        "GO",
        "REACT",
        "MetaCyc",
        "KEGG.MODULE"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/BiologicalProcess",
      "exact_mappings": [
        "GO:0008150",
        "SIO:000006",
        "WIKIDATA:Q2996394"
      ],
      "broad_mappings": [
        "WIKIDATA:P682"
      ],
      "description": "One or more causally connected executions of molecular functions",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalProcessOrActivity",
      "mixins": [
        "Occurrent",
        "OntologyClass"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "has_input",
        "has_output",
        "enabled_by"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/BiologicalProcess",
      "@type": "ClassDefinition"
    },
    {
      "name": "Pathway",
      "id_prefixes": [
        "GO",
        "REACT",
        "KEGG",
        "SMPDB",
        "MSigDB",
        "PHARMGKB.PATHWAYS",
        "WIKIPATHWAYS",
        "FB",
        "PANTHER.PATHWAY"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Pathway",
      "exact_mappings": [
        "PW:0000001",
        "WIKIDATA:Q4915012"
      ],
      "narrow_mappings": [
        "SIO:010526",
        "GO:0007165"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalProcess",
      "mixins": [
        "OntologyClass"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "has_input",
        "has_output",
        "enabled_by"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Pathway",
      "@type": "ClassDefinition"
    },
    {
      "name": "PhysiologicalProcess",
      "id_prefixes": [
        "GO",
        "REACT"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/PhysiologicalProcess",
      "aliases": [
        "physiology"
      ],
      "exact_mappings": [
        "UMLSSC:T039",
        "UMLSST:phsf",
        "WIKIDATA:Q30892994"
      ],
      "close_mappings": [
        "UMLSSG:PHYS"
      ],
      "narrow_mappings": [
        "UMLSSC:T040",
        "UMLSST:orgf",
        "UMLSSC:T042",
        "UMLSST:ortf",
        "UMLSSC:T043",
        "UMLSST:celf",
        "UMLSSC:T045",
        "UMLSST:genf"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalProcess",
      "mixins": [
        "OntologyClass"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "has_input",
        "has_output",
        "enabled_by"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PhysiologicalProcess",
      "@type": "ClassDefinition"
    },
    {
      "name": "Behavior",
      "definition_uri": "https://w3id.org/biolink/vocab/Behavior",
      "exact_mappings": [
        "GO:0007610",
        "UMLSSC:T053",
        "UMLSST:bhvr"
      ],
      "narrow_mappings": [
        "UMLSSC:T041",
        "UMLSST:menp",
        "UMLSSC:T054",
        "UMLSST:socb",
        "UMLSSC:T055",
        "UMLSST:inbe"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalProcess",
      "mixins": [
        "OntologyClass"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "has_input",
        "has_output",
        "enabled_by"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Behavior",
      "@type": "ClassDefinition"
    },
    {
      "name": "Death",
      "definition_uri": "https://w3id.org/biolink/vocab/Death",
      "exact_mappings": [
        "GO:0016265"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalProcess",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "has_input",
        "has_output",
        "enabled_by"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Death",
      "@type": "ClassDefinition"
    },
    {
      "name": "Mixture",
      "definition_uri": "https://w3id.org/biolink/vocab/Mixture",
      "description": "The physical combination of two or more molecular entities in which the identities are retained and are mixed in the form of solutions, suspensions and colloids.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "has_constituent"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Mixture",
      "@type": "ClassDefinition"
    },
    {
      "name": "ChemicalSubstance",
      "id_prefixes": [
        "PUBCHEM.COMPOUND",
        "CHEMBL.COMPOUND",
        "UNII",
        "CHEBI",
        "DRUGBANK",
        "MESH",
        "CAS",
        "DrugCentral",
        "GTOPDB",
        "HMDB",
        "KEGG.COMPOUND",
        "ChemBank",
        "Aeolus",
        "PUBCHEM.SUBSTANCE",
        "SIDER.DRUG",
        "INCHI",
        "INCHIKEY",
        "KEGG.GLYCAN",
        "KEGG.DRUG",
        "KEGG.DGROUP",
        "KEGG.ENVIRON"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/ChemicalSubstance",
      "exact_mappings": [
        "SIO:010004",
        "WIKIDATA:Q79529",
        "UMLSSC:T103",
        "UMLSST:chem"
      ],
      "narrow_mappings": [
        "CHEBI:24431",
        "UMLSSC:T104",
        "UMLSST:chvs",
        "UMLSSC:T109",
        "UMLSST:orch",
        "UMLSSC:T114",
        "UMLSST:nnon",
        "UMLSSC:T120",
        "UMLSST:chvf",
        "UMLSSC:T122",
        "UMLSST:bodm",
        "UMLSSC:T130",
        "UMLSST:irda",
        "UMLSSC:T131",
        "UMLSST:hops",
        "UMLSSC:T196",
        "UMLSST:elii",
        "UMLSSC:T197",
        "UMLSST:inch"
      ],
      "broad_mappings": [
        "UMLSSC:T167",
        "UMLSST:sbst"
      ],
      "description": "May be a chemical entity or a formulation with a chemical entity as active ingredient, or a complex material with multiple chemical entities as part",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "MolecularEntity",
      "mixins": [
        "OntologyClass"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ChemicalSubstance",
      "@type": "ClassDefinition"
    },
    {
      "name": "Carbohydrate",
      "id_prefixes": [
        "PUBCHEM.SUBSTANCE"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Carbohydrate",
      "exact_mappings": [
        "UMLSSC:T088",
        "UMLSST:crbs"
      ],
      "deprecated": "This class will be removed from the Biolink model",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ChemicalSubstance",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Carbohydrate",
      "@type": "ClassDefinition"
    },
    {
      "name": "ProcessedMaterial",
      "definition_uri": "https://w3id.org/biolink/vocab/ProcessedMaterial",
      "exact_mappings": [
        "OBI:0000047"
      ],
      "description": "A chemical substance (often a mixture) processed for consumption for nutritional, medical or technical use.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ChemicalSubstance",
      "mixins": [
        "Mixture",
        "OntologyClass"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite",
        "has_constituent"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ProcessedMaterial",
      "@type": "ClassDefinition"
    },
    {
      "name": "Drug",
      "id_prefixes": [
        "RXCUI",
        "NDC",
        "PHARMGKB.DRUG"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Drug",
      "exact_mappings": [
        "WIKIDATA:Q12140",
        "CHEBI:23888",
        "UMLSSC:T200",
        "UMLSST:clnd"
      ],
      "narrow_mappings": [
        "UMLSSC:T195",
        "UMLSST:antb"
      ],
      "broad_mappings": [
        "UMLSSC:T121",
        "UMLSST:phsu"
      ],
      "description": "A substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease",
      "comments": [
        "The CHEBI ID represents a role rather than a substance"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "MolecularEntity",
      "mixins": [
        "Mixture",
        "ChemicalOrDrugOrTreatment",
        "OntologyClass"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_constituent"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Drug",
      "@type": "ClassDefinition"
    },
    {
      "name": "FoodComponent",
      "definition_uri": "https://w3id.org/biolink/vocab/FoodComponent",
      "related_mappings": [
        "CHEBI:78295"
      ],
      "deprecated": "Food component is replaced by a slot/role of chemical substance and will be removed from the Biolink model.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ChemicalSubstance",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/FoodComponent",
      "@type": "ClassDefinition"
    },
    {
      "name": "EnvironmentalFoodContaminant",
      "definition_uri": "https://w3id.org/biolink/vocab/EnvironmentalFoodContaminant",
      "related_mappings": [
        "CHEBI:78299"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ChemicalSubstance",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/EnvironmentalFoodContaminant",
      "@type": "ClassDefinition"
    },
    {
      "name": "FoodAdditive",
      "definition_uri": "https://w3id.org/biolink/vocab/FoodAdditive",
      "related_mappings": [
        "CHEBI:64047"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ChemicalSubstance",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/FoodAdditive",
      "@type": "ClassDefinition"
    },
    {
      "name": "Nutrient",
      "definition_uri": "https://w3id.org/biolink/vocab/Nutrient",
      "related_mappings": [
        "CHEBI:33284"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ChemicalSubstance",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Nutrient",
      "@type": "ClassDefinition"
    },
    {
      "name": "Macronutrient",
      "definition_uri": "https://w3id.org/biolink/vocab/Macronutrient",
      "related_mappings": [
        "CHEBI:33937"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Nutrient",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Macronutrient",
      "@type": "ClassDefinition"
    },
    {
      "name": "Micronutrient",
      "definition_uri": "https://w3id.org/biolink/vocab/Micronutrient",
      "related_mappings": [
        "CHEBI:27027"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Nutrient",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Micronutrient",
      "@type": "ClassDefinition"
    },
    {
      "name": "Vitamin",
      "definition_uri": "https://w3id.org/biolink/vocab/Vitamin",
      "related_mappings": [
        "CHEBI:33229",
        "UMLSSC:T127",
        "UMLSST:vita"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Micronutrient",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Vitamin",
      "@type": "ClassDefinition"
    },
    {
      "name": "Food",
      "id_prefixes": [
        "foodb.compound"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Food",
      "exact_mappings": [
        "UMLSSC:T168",
        "UMLSST:food"
      ],
      "description": "A substance consumed by a living organism as a source of nutrition",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "MolecularEntity",
      "mixins": [
        "Mixture"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_constituent"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Food",
      "@type": "ClassDefinition"
    },
    {
      "name": "Metabolite",
      "definition_uri": "https://w3id.org/biolink/vocab/Metabolite",
      "exact_mappings": [
        "CHEBI:25212"
      ],
      "description": "Any intermediate or product resulting from metabolism. Includes primary and secondary metabolites.",
      "deprecated": "Metabolite is replaced by a slot/role of chemical substance and will be removed  from the Biolink model.",
      "comments": [
        "The CHEBI ID represents a role rather than a substance"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ChemicalSubstance",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Metabolite",
      "@type": "ClassDefinition"
    },
    {
      "name": "OrganismAttribute",
      "definition_uri": "https://w3id.org/biolink/vocab/OrganismAttribute",
      "exact_mappings": [
        "UMLSSC:T032",
        "UMLSST:orga"
      ],
      "description": "describes a characteristic of an organismal entity.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Attribute",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/OrganismAttribute",
      "@type": "ClassDefinition"
    },
    {
      "name": "PhenotypicQuality",
      "definition_uri": "https://w3id.org/biolink/vocab/PhenotypicQuality",
      "aliases": [
        "phenotypic properties"
      ],
      "mappings": [
        "PATO:0000001"
      ],
      "description": "A property of a phenotype",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OrganismAttribute",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PhenotypicQuality",
      "@type": "ClassDefinition"
    },
    {
      "name": "Inheritance",
      "definition_uri": "https://w3id.org/biolink/vocab/Inheritance",
      "exact_mappings": [
        "HP:0000005",
        "GENO:0000141",
        "NCIT:C45827"
      ],
      "description": "The pattern or 'mode' in which a particular genetic trait or disorder is passed from one generation to the next, e.g. autosomal dominant, autosomal recessive, etc.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OrganismAttribute",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Inheritance",
      "@type": "ClassDefinition"
    },
    {
      "name": "OrganismalEntity",
      "definition_uri": "https://w3id.org/biolink/vocab/OrganismalEntity",
      "exact_mappings": [
        "WIKIDATA:Q7239",
        "UMLSSG:LIVB"
      ],
      "description": "A named entity that is either a part of an organism, a whole organism, population or clade of organisms, excluding molecular entities",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalEntity",
      "abstract": true,
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/OrganismalEntity",
      "@type": "ClassDefinition"
    },
    {
      "name": "LifeStage",
      "definition_uri": "https://w3id.org/biolink/vocab/LifeStage",
      "exact_mappings": [
        "UBERON:0000105"
      ],
      "narrow_mappings": [
        "HsapDv:0000000"
      ],
      "description": "A stage of development or growth of an organism, including post-natal adult stages",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OrganismalEntity",
      "mixins": [
        "ThingWithTaxon"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/LifeStage",
      "@type": "ClassDefinition"
    },
    {
      "name": "IndividualOrganism",
      "id_prefixes": [
        "ORCID"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/IndividualOrganism",
      "aliases": [
        "organism"
      ],
      "exact_mappings": [
        "SIO:010000",
        "UMLSSC:T001",
        "UMLSST:orgm"
      ],
      "narrow_mappings": [
        "WIKIDATA:Q795052",
        "foaf:Person"
      ],
      "description": "An instance of an organism. For example, Richard Nixon, Charles Darwin, my pet cat. Example ID: ORCID:0000-0002-5355-2576",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OrganismalEntity",
      "mixins": [
        "ThingWithTaxon"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/IndividualOrganism",
      "@type": "ClassDefinition"
    },
    {
      "name": "PopulationOfIndividualOrganisms",
      "id_prefixes": [
        "HANCESTRO"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/PopulationOfIndividualOrganisms",
      "local_names": [
        {
          "local_name_source": "ga4gh",
          "local_name_value": "population",
          "@type": "LocalName"
        },
        {
          "local_name_source": "agr",
          "local_name_value": "population",
          "@type": "LocalName"
        }
      ],
      "exact_mappings": [
        "PCO:0000001",
        "SIO:001061",
        "UMLSSC:T098",
        "UMLSST:popg",
        "OBI:0000181"
      ],
      "narrow_mappings": [
        "UMLSSC:T099",
        "UMLSST:famg",
        "UMLSSC:T100",
        "UMLSST:aggp",
        "UMLSSC:T101",
        "UMLSST:podg"
      ],
      "description": "A collection of individuals from the same taxonomic class distinguished by one or more characteristics.  Characteristics can include, but are not limited to, shared geographic location, genetics, phenotypes [Alliance for Genome Resources]",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OrganismalEntity",
      "mixins": [
        "ThingWithTaxon"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PopulationOfIndividualOrganisms",
      "@type": "ClassDefinition"
    },
    {
      "name": "DiseaseOrPhenotypicFeature",
      "definition_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeature",
      "aliases": [
        "phenome"
      ],
      "narrow_mappings": [
        "UMLSSC:T033",
        "UMLSST:fndg"
      ],
      "description": "Either one of a disease or an individual phenotypic feature. Some knowledge resources such as Monarch treat these as distinct, others such as MESH conflate.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalEntity",
      "mixins": [
        "ThingWithTaxon"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeature",
      "union_of": [
        "Disease",
        "PhenotypicFeature"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "Disease",
      "id_prefixes": [
        "MONDO",
        "DOID",
        "OMIM",
        "ORPHANET",
        "EFO",
        "UMLS",
        "MESH",
        "MEDDRA",
        "NCIT",
        "SNOMEDCT",
        "medgen",
        "ICD10",
        "ICD9",
        "ICD0",
        "KEGG.DISEASE",
        "HP",
        "MP"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Disease",
      "aliases": [
        "condition",
        "disorder",
        "medical condition"
      ],
      "exact_mappings": [
        "MONDO:0000001",
        "DOID:4",
        "NCIT:C2991",
        "WIKIDATA:Q12136",
        "SIO:010299",
        "UMLSSG:DISO",
        "UMLSSC:T047",
        "UMLSST:dsyn"
      ],
      "narrow_mappings": [
        "UMLSSC:T019",
        "UMLSST:cgab",
        "UMLSSC:T020",
        "UMLSST:acab",
        "UMLSSC:T037",
        "UMLSST:inpo",
        "UMLSSC:T046",
        "UMLSST:patf",
        "UMLSSC:T048",
        "UMLSST:mobd",
        "UMLSSC:T049",
        "UMLSST:comd",
        "UMLSSC:T190",
        "UMLSST:anab",
        "UMLSSC:T191",
        "UMLSST:neop"
      ],
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "DiseaseOrPhenotypicFeature",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Disease",
      "@type": "ClassDefinition"
    },
    {
      "name": "PhenotypicFeature",
      "id_prefixes": [
        "HP",
        "EFO",
        "NCIT",
        "UMLS",
        "MEDDRA",
        "MP",
        "ZP",
        "UPHENO",
        "APO",
        "FBcv",
        "WBPhenotype",
        "SNOMEDCT",
        "MESH"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/PhenotypicFeature",
      "aliases": [
        "sign",
        "symptom",
        "phenotype",
        "trait",
        "endophenotype"
      ],
      "exact_mappings": [
        "UPHENO:0001001",
        "SIO:010056",
        "WIKIDATA:Q104053"
      ],
      "narrow_mappings": [
        "UMLSSC:T184",
        "UMLSST:sosy",
        "WIKIDATA:Q169872",
        "WIKIDATA:Q25203551"
      ],
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "DiseaseOrPhenotypicFeature",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PhenotypicFeature",
      "@type": "ClassDefinition"
    },
    {
      "name": "BehavioralFeature",
      "definition_uri": "https://w3id.org/biolink/vocab/BehavioralFeature",
      "exact_mappings": [
        "NBO:0000243"
      ],
      "description": "A phenotypic feature which is behavioral in nature.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PhenotypicFeature",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/BehavioralFeature",
      "@type": "ClassDefinition"
    },
    {
      "name": "AnatomicalEntity",
      "id_prefixes": [
        "UBERON",
        "GO",
        "CL",
        "UMLS",
        "MESH",
        "NCIT"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/AnatomicalEntity",
      "exact_mappings": [
        "UBERON:0001062",
        "WIKIDATA:Q4936952",
        "UMLSSG:ANAT"
      ],
      "narrow_mappings": [
        "UMLSSC:T022",
        "UMLSST:bdsy",
        "UMLSSC:T029",
        "UMLSST:blor",
        "UMLSSC:T030",
        "UMLSST:bsoj",
        "UMLSSC:T031",
        "UMLSST:bdsu"
      ],
      "description": "A subcellular location, cell type or gross anatomical part",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OrganismalEntity",
      "mixins": [
        "ThingWithTaxon",
        "PhysicalEssence"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/AnatomicalEntity",
      "@type": "ClassDefinition"
    },
    {
      "name": "CellularComponent",
      "id_prefixes": [
        "GO",
        "MESH",
        "UMLS",
        "NCIT",
        "SNOMEDCT",
        "CL",
        "UBERON"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/CellularComponent",
      "exact_mappings": [
        "GO:0005575",
        "SIO:001400",
        "WIKIDATA:Q5058355",
        "UMLSSC:T026",
        "UMLSST:celc"
      ],
      "broad_mappings": [
        "WIKIDATA:P681"
      ],
      "description": "A location in or around a cell",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "AnatomicalEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/CellularComponent",
      "@type": "ClassDefinition"
    },
    {
      "name": "Cell",
      "id_prefixes": [
        "CL",
        "PO",
        "UMLS",
        "NCIT",
        "MESH",
        "UBERON",
        "SNOMEDCT"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Cell",
      "exact_mappings": [
        "GO:0005623",
        "CL:0000000",
        "SIO:010001",
        "WIKIDATA:Q7868",
        "UMLSSC:T025",
        "UMLSST:cell"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "AnatomicalEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Cell",
      "@type": "ClassDefinition"
    },
    {
      "name": "CellLine",
      "id_prefixes": [
        "CLO"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/CellLine",
      "exact_mappings": [
        "CLO:0000031"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OrganismalEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/CellLine",
      "@type": "ClassDefinition"
    },
    {
      "name": "GrossAnatomicalStructure",
      "id_prefixes": [
        "UBERON",
        "UMLS",
        "MESH",
        "NCIT",
        "PO",
        "FAO"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/GrossAnatomicalStructure",
      "aliases": [
        "tissue",
        "organ"
      ],
      "exact_mappings": [
        "UBERON:0010000",
        "WIKIDATA:Q4936952",
        "UMLSSC:T017",
        "UMLSST:anst",
        "UMLSSC:T021",
        "UMLSST:ffas"
      ],
      "narrow_mappings": [
        "UMLSSC:T023",
        "UMLSST:bpoc",
        "UMLSSC:T024",
        "UMLSST:tisu",
        "UMLSSC:T018",
        "UMLSST:emst"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "AnatomicalEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GrossAnatomicalStructure",
      "@type": "ClassDefinition"
    },
    {
      "name": "MacromolecularMachineMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/MacromolecularMachineMixin",
      "description": "A union of gene locus, gene product, and macromolecular complex mixin. These are the basic units of function in a cell. They either carry out individual biological activities, or they encode molecules which do this.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "macromolecular_machine_mixin_name"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/MacromolecularMachineMixin",
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneOrGeneProduct",
      "id_prefixes": [
        "CHEMBL.TARGET",
        "IUPHAR.FAMILY"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/GeneOrGeneProduct",
      "description": "A union of gene loci or gene products. Frequently an identifier for one will be used as proxy for another",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "MacromolecularMachineMixin",
      "mixin": true,
      "slots": [
        "macromolecular_machine_mixin_name"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeneOrGeneProduct",
      "@type": "ClassDefinition"
    },
    {
      "name": "Gene",
      "id_prefixes": [
        "NCBIGene",
        "ENSEMBL",
        "HGNC",
        "MGI",
        "ZFIN",
        "dictyBase",
        "WB",
        "WormBase",
        "FB",
        "FB",
        "RGD",
        "SGD",
        "POMBASE",
        "OMIM",
        "KEGG.GENE",
        "UMLS"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Gene",
      "aliases": [
        "locus"
      ],
      "exact_mappings": [
        "SO:0000704",
        "SIO:010035",
        "WIKIDATA:Q7187"
      ],
      "description": "A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene locus may include regulatory regions, transcribed regions and/or other functional sequence regions.",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenomicEntity",
      "mixins": [
        "GeneOrGeneProduct"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence",
        "symbol",
        "synonym",
        "xref"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Gene",
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneProductMixin",
      "id_prefixes": [
        "UniProtKB",
        "gtpo",
        "PR"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/GeneProductMixin",
      "exact_mappings": [
        "WIKIDATA:Q424689",
        "GENO:0000907",
        "NCIT:C26548"
      ],
      "description": "The functional molecular product of a single gene locus. Gene products are either proteins or functional RNA molecules.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GeneOrGeneProduct",
      "mixin": true,
      "slots": [
        "macromolecular_machine_mixin_name",
        "synonym",
        "xref"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeneProductMixin",
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneProductIsoformMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneProductIsoformMixin",
      "description": "This is an abstract class that can be mixed in with different kinds of gene products to indicate that the gene product is intended to represent a specific isoform rather than a canonical or reference or generic product. The designation of canonical or reference may be arbitrary, or it may represent the superclass of all isoforms.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GeneProductMixin",
      "mixin": true,
      "slots": [
        "macromolecular_machine_mixin_name",
        "synonym",
        "xref"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeneProductIsoformMixin",
      "@type": "ClassDefinition"
    },
    {
      "name": "MacromolecularComplexMixin",
      "id_prefixes": [
        "INTACT",
        "GO",
        "PR",
        "REACT"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/MacromolecularComplexMixin",
      "exact_mappings": [
        "GO:0032991",
        "WIKIDATA:Q22325163"
      ],
      "description": "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "MacromolecularMachineMixin",
      "mixin": true,
      "slots": [
        "macromolecular_machine_mixin_name"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/MacromolecularComplexMixin",
      "@type": "ClassDefinition"
    },
    {
      "name": "GenomicEntity",
      "definition_uri": "https://w3id.org/biolink/vocab/GenomicEntity",
      "aliases": [
        "sequence feature"
      ],
      "exact_mappings": [
        "UMLSSG:GENE",
        "SO:0000110",
        "GENO:0000897"
      ],
      "narrow_mappings": [
        "UMLSSC:T028",
        "UMLSST:gngm",
        "UMLSSC:T086",
        "UMLSST:nusq"
      ],
      "description": "an entity that can either be directly located on a genome (gene, transcript, exon, regulatory region) or is encoded in a genome (protein)",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "MolecularEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GenomicEntity",
      "@type": "ClassDefinition"
    },
    {
      "name": "Genome",
      "definition_uri": "https://w3id.org/biolink/vocab/Genome",
      "exact_mappings": [
        "SO:0001026",
        "SIO:000984",
        "WIKIDATA:Q7020"
      ],
      "description": "A genome is the sum of genetic material within a cell or virion.",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenomicEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Genome",
      "@type": "ClassDefinition"
    },
    {
      "name": "Exon",
      "definition_uri": "https://w3id.org/biolink/vocab/Exon",
      "exact_mappings": [
        "SO:0000147",
        "SIO:010445",
        "WIKIDATA:Q373027"
      ],
      "description": "A region of the transcript sequence within a gene which is not removed from the primary RNA transcript by RNA splicing.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenomicEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Exon",
      "@type": "ClassDefinition"
    },
    {
      "name": "Transcript",
      "id_prefixes": [
        "ENSEMBL",
        "FB"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Transcript",
      "exact_mappings": [
        "SO:0000673",
        "SIO:010450",
        "WIKIDATA:Q7243183"
      ],
      "description": "An RNA synthesized on a DNA or RNA template by an RNA polymerase.",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenomicEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Transcript",
      "@type": "ClassDefinition"
    },
    {
      "name": "CodingSequence",
      "definition_uri": "https://w3id.org/biolink/vocab/CodingSequence",
      "exact_mappings": [
        "SO:0000316",
        "SIO:001390"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenomicEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/CodingSequence",
      "@type": "ClassDefinition"
    },
    {
      "name": "Protein",
      "id_prefixes": [
        "UniProtKB",
        "PR",
        "ENSEMBL",
        "FB",
        "UMLS"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Protein",
      "aliases": [
        "polypeptide"
      ],
      "exact_mappings": [
        "PR:000000001",
        "SIO:010043",
        "WIKIDATA:Q8054",
        "SO:0000104",
        "UMLSSC:T087",
        "UMLSST:amas"
      ],
      "broad_mappings": [
        "UMLSSC:T116",
        "UMLSST:aapp"
      ],
      "description": "A gene product that is composed of a chain of amino acid sequences and is produced by ribosome-mediated translation of mRNA",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenomicEntity",
      "mixins": [
        "GeneProductMixin"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence",
        "synonym",
        "xref"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Protein",
      "@type": "ClassDefinition"
    },
    {
      "name": "ProteinIsoform",
      "id_prefixes": [
        "UniProtKB",
        "UNIPROT.ISOFORM",
        "PR",
        "ENSEMBL"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/ProteinIsoform",
      "aliases": [
        "proteoform"
      ],
      "description": "Represents a protein that is a specific isoform of the canonical or reference protein. See https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114032/",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Protein",
      "mixins": [
        "GeneProductIsoformMixin"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence",
        "synonym",
        "xref"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ProteinIsoform",
      "@type": "ClassDefinition"
    },
    {
      "name": "RNAProduct",
      "id_prefixes": [
        "RNACENTRAL"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/RNAProduct",
      "exact_mappings": [
        "CHEBI:33697",
        "WIKIDATA:Q11053"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Transcript",
      "mixins": [
        "GeneProductMixin"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence",
        "synonym",
        "xref"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/RNAProduct",
      "@type": "ClassDefinition"
    },
    {
      "name": "RNAProductIsoform",
      "id_prefixes": [
        "RNACENTRAL"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/RNAProductIsoform",
      "description": "Represents a protein that is a specific isoform of the canonical or reference RNA",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "RNAProduct",
      "mixins": [
        "GeneProductIsoformMixin"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence",
        "synonym",
        "xref"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/RNAProductIsoform",
      "@type": "ClassDefinition"
    },
    {
      "name": "NoncodingRNAProduct",
      "id_prefixes": [
        "RNACENTRAL",
        "NCBIGene",
        "ENSEMBL"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/NoncodingRNAProduct",
      "exact_mappings": [
        "SO:0000655",
        "SIO:001235"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "RNAProduct",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence",
        "synonym",
        "xref"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/NoncodingRNAProduct",
      "@type": "ClassDefinition"
    },
    {
      "name": "MicroRNA",
      "id_prefixes": [
        "MIR",
        "HGNC",
        "WormBase"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/MicroRNA",
      "exact_mappings": [
        "SO:0000276",
        "SIO:001397",
        "WIKIDATA:Q310899"
      ],
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NoncodingRNAProduct",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence",
        "synonym",
        "xref"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/MicroRNA",
      "@type": "ClassDefinition"
    },
    {
      "name": "SiRNA",
      "id_prefixes": [
        "MIR",
        "HGNC",
        "WormBase"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/SiRNA",
      "aliases": [
        "small interfering RNA",
        "RNAi"
      ],
      "exact_mappings": [
        "SO:0000646",
        "WIKIDATA:Q203221"
      ],
      "description": "A small RNA molecule that is the product of a longer exogenous or endogenous dsRNA, which is either a bimolecular duplex or very long hairpin, processed (via the Dicer pathway) such that numerous siRNAs accumulate from both strands of the dsRNA. SRNAs trigger the cleavage of their target molecules.",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NoncodingRNAProduct",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence",
        "synonym",
        "xref"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/SiRNA",
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneGroupingMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneGroupingMixin",
      "description": "any grouping of multiple genes or gene products",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "has_gene_or_gene_product"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeneGroupingMixin",
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneFamily",
      "id_prefixes": [
        "PANTHER.FAMILY",
        "HGNC.FAMILY",
        "FB",
        "interpro",
        "CATH",
        "CDD",
        "HAMAP",
        "PFAM",
        "PIRSF",
        "PRINTS",
        "PRODOM",
        "PROSITE",
        "SMART",
        "SUPFAM",
        "TIGRFAM",
        "CATH.SUPERFAMILY",
        "RFAM",
        "KEGG.ORTHOLOGY",
        "EGGNOG"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/GeneFamily",
      "aliases": [
        "orthogroup",
        "protein family"
      ],
      "exact_mappings": [
        "NCIT:C26004",
        "WIKIDATA:Q2278983"
      ],
      "narrow_mappings": [
        "SIO:001380",
        "NCIT:C20130",
        "WIKIDATA:Q417841"
      ],
      "description": "any grouping of multiple genes or gene products related by common descent",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "MolecularEntity",
      "mixins": [
        "GeneGroupingMixin"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_gene_or_gene_product"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeneFamily",
      "@type": "ClassDefinition"
    },
    {
      "name": "Zygosity",
      "definition_uri": "https://w3id.org/biolink/vocab/Zygosity",
      "exact_mappings": [
        "GENO:0000133"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Attribute",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Zygosity",
      "@type": "ClassDefinition"
    },
    {
      "name": "Genotype",
      "id_prefixes": [
        "ZFIN",
        "FB"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/Genotype",
      "exact_mappings": [
        "GENO:0000536",
        "SIO:001079"
      ],
      "description": "An information content entity that describes a genome by specifying the total variation in genomic sequence and/or gene expression, relative to some established background",
      "comments": [
        "Consider renaming as genotypic entity"
      ],
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenomicEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence",
        "has_zygosity"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Genotype",
      "@type": "ClassDefinition"
    },
    {
      "name": "Haplotype",
      "definition_uri": "https://w3id.org/biolink/vocab/Haplotype",
      "exact_mappings": [
        "GENO:0000871",
        "SO:0001024",
        "VMC:Haplotype"
      ],
      "description": "A set of zero or more Alleles on a single instance of a Sequence[VMC]",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenomicEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Haplotype",
      "@type": "ClassDefinition"
    },
    {
      "name": "SequenceVariant",
      "id_prefixes": [
        "CAID",
        "CLINVAR",
        "ClinVarVariant",
        "WIKIDATA",
        "DBSNP",
        "DBSNP",
        "MGI",
        "ZFIN",
        "FB",
        "WB",
        "WormBase"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/SequenceVariant",
      "aliases": [
        "allele"
      ],
      "local_names": [
        {
          "local_name_source": "agr",
          "local_name_value": "allele",
          "@type": "LocalName"
        }
      ],
      "exact_mappings": [
        "GENO:0000002",
        "WIKIDATA:Q15304597",
        "SIO:010277",
        "VMC:Allele",
        "SO:0001059"
      ],
      "broad_mappings": [
        "SO:0001060"
      ],
      "description": "An allele that varies in its sequence from what is considered the reference allele at that locus.",
      "alt_descriptions": [
        {
          "source": "AGR",
          "description": "An entity that describes a single affected, endogenous allele. These can be of any type that matches that definition",
          "@type": "AltDescription"
        },
        {
          "source": "VMC",
          "description": "A contiguous change at a Location",
          "@type": "AltDescription"
        }
      ],
      "comments": [
        "This class is for modeling the specific state at a locus. A single DBSNP rs ID could correspond to more than one sequence variants (e.g CIViC:1252 and CIViC:1253, two distinct BRCA2 alleles for rs28897743)"
      ],
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenomicEntity",
      "slots": [
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "sequence_variant_has_gene",
        "sequence_variant_has_biological_sequence",
        "sequence_variant_id"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/SequenceVariant",
      "@type": "ClassDefinition"
    },
    {
      "name": "Snv",
      "definition_uri": "https://w3id.org/biolink/vocab/Snv",
      "aliases": [
        "single nucleotide variant",
        "single nucleotide polymorphism",
        "snp"
      ],
      "exact_mappings": [
        "SO:0001483"
      ],
      "description": "SNVs are single nucleotide positions in genomic DNA at which different sequence alternatives exist",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "SequenceVariant",
      "slots": [
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "sequence_variant_has_gene",
        "sequence_variant_has_biological_sequence",
        "sequence_variant_id"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Snv",
      "@type": "ClassDefinition"
    },
    {
      "name": "ReagentTargetedGene",
      "definition_uri": "https://w3id.org/biolink/vocab/ReagentTargetedGene",
      "exact_mappings": [
        "GENO:0000504"
      ],
      "description": "A gene altered in its expression level in the context of some experiment as a result of being targeted by gene-knockdown reagent(s) such as a morpholino or RNAi.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenomicEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ReagentTargetedGene",
      "@type": "ClassDefinition"
    },
    {
      "name": "ClinicalAttribute",
      "definition_uri": "https://w3id.org/biolink/vocab/ClinicalAttribute",
      "exact_mappings": [
        "UMLSSC:T201",
        "UMLSST:clna"
      ],
      "description": "Attributes relating to a clinical manifestation",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Attribute",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ClinicalAttribute",
      "@type": "ClassDefinition"
    },
    {
      "name": "ClinicalMeasurement",
      "definition_uri": "https://w3id.org/biolink/vocab/ClinicalMeasurement",
      "exact_mappings": [
        "EFO:0001444"
      ],
      "description": "A clinical measurement is a special kind of attribute which results from a laboratory observation from a subject individual or sample. Measurements can be connected to their subject by the 'has attribute' slot.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ClinicalAttribute",
      "slots": [
        "attribute_name",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source",
        "clinical_measurement_has_attribute_type"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ClinicalMeasurement",
      "@type": "ClassDefinition"
    },
    {
      "name": "ClinicalModifier",
      "definition_uri": "https://w3id.org/biolink/vocab/ClinicalModifier",
      "exact_mappings": [
        "HP:0012823"
      ],
      "description": "Used to characterize and specify the phenotypic abnormalities defined in the phenotypic abnormality sub-ontology, with respect to severity, laterality, and other aspects",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ClinicalAttribute",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ClinicalModifier",
      "@type": "ClassDefinition"
    },
    {
      "name": "ClinicalCourse",
      "definition_uri": "https://w3id.org/biolink/vocab/ClinicalCourse",
      "exact_mappings": [
        "HP:0031797"
      ],
      "description": "The course a disease typically takes from its onset, progression in time, and eventual resolution or death of the affected individual",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ClinicalAttribute",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ClinicalCourse",
      "@type": "ClassDefinition"
    },
    {
      "name": "Onset",
      "definition_uri": "https://w3id.org/biolink/vocab/Onset",
      "exact_mappings": [
        "HP:0003674"
      ],
      "description": "The age group in which (disease) symptom manifestations appear",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ClinicalCourse",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Onset",
      "@type": "ClassDefinition"
    },
    {
      "name": "ClinicalEntity",
      "definition_uri": "https://w3id.org/biolink/vocab/ClinicalEntity",
      "description": "Any entity or process that exists in the clinical domain and outside the biological realm. Diseases are placed under biological entities",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ClinicalEntity",
      "@type": "ClassDefinition"
    },
    {
      "name": "ClinicalTrial",
      "definition_uri": "https://w3id.org/biolink/vocab/ClinicalTrial",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ClinicalEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ClinicalTrial",
      "@type": "ClassDefinition"
    },
    {
      "name": "ClinicalIntervention",
      "definition_uri": "https://w3id.org/biolink/vocab/ClinicalIntervention",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ClinicalEntity",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ClinicalIntervention",
      "@type": "ClassDefinition"
    },
    {
      "name": "ClinicalFinding",
      "id_prefixes": [
        "LOINC",
        "NCIT",
        "EFO"
      ],
      "definition_uri": "https://w3id.org/biolink/vocab/ClinicalFinding",
      "description": "this category is currently considered broad enough to tag clinical lab measurements and other biological attributes taken as 'clinical traits' with some statistical score, for example, a p value in genetic associations.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PhenotypicFeature",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "in_taxon",
        "clinical_finding_has_attribute"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ClinicalFinding",
      "@type": "ClassDefinition"
    },
    {
      "name": "Hospitalization",
      "definition_uri": "https://w3id.org/biolink/vocab/Hospitalization",
      "exact_mappings": [
        "SNOMEDCT:32485007",
        "WIKIDATA:Q3140971"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ClinicalIntervention",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Hospitalization",
      "@type": "ClassDefinition"
    },
    {
      "name": "SocioeconomicAttribute",
      "definition_uri": "https://w3id.org/biolink/vocab/SocioeconomicAttribute",
      "description": "Attributes relating to a socioeconomic manifestation",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Attribute",
      "slots": [
        "attribute_name",
        "has_attribute_type",
        "has_quantitative_value",
        "has_qualitative_value",
        "iri",
        "source"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/SocioeconomicAttribute",
      "@type": "ClassDefinition"
    },
    {
      "name": "Case",
      "definition_uri": "https://w3id.org/biolink/vocab/Case",
      "aliases": [
        "patient",
        "proband"
      ],
      "description": "An individual (human) organism that has a patient role in some clinical context.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "IndividualOrganism",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Case",
      "@type": "ClassDefinition"
    },
    {
      "name": "Cohort",
      "definition_uri": "https://w3id.org/biolink/vocab/Cohort",
      "exact_mappings": [
        "WIKIDATA:Q1303415"
      ],
      "narrow_mappings": [
        "UMLSSC:T097",
        "UMLSST:prog",
        "UMLSSC:T099",
        "UMLSST:famg",
        "UMLSSC:T100",
        "UMLSST:aggp",
        "UMLSSC:T101",
        "UMLSST:podg"
      ],
      "description": "A group of people banded together or treated as a group who share common characteristics. A cohort 'study' is a particular form of longitudinal study that samples a cohort, performing a cross-section at intervals through time.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "StudyPopulation",
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Cohort",
      "@type": "ClassDefinition"
    },
    {
      "name": "ExposureEvent",
      "definition_uri": "https://w3id.org/biolink/vocab/ExposureEvent",
      "aliases": [
        "exposure",
        "experimental condition"
      ],
      "exact_mappings": [
        "XCO:0000000"
      ],
      "broad_mappings": [
        "UMLSSC:T051",
        "UMLSST:evnt"
      ],
      "description": "A (possibly time bounded) incidence of a feature of the environment of an organism that influences one or more phenotypic features of that organism, potentially mediated by genes",
      "in_subset": [
        "model_organism_database"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "timepoint"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ExposureEvent",
      "@type": "ClassDefinition"
    },
    {
      "name": "GenomicBackgroundExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/GenomicBackgroundExposure",
      "description": "A genomic background exposure is where an individual's specific genomic background of genes, sequence variants or other pre-existing genomic conditions constitute a kind of 'exposure' to the organism, leading to or influencing an outcome.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenomicEntity",
      "mixins": [
        "ExposureEvent",
        "GeneGroupingMixin"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_biological_sequence",
        "timepoint",
        "has_gene_or_gene_product"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GenomicBackgroundExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "PathologicalEntityMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/PathologicalEntityMixin",
      "exact_mappings": [
        "MPATH:0"
      ],
      "narrow_mappings": [
        "HP:0000118"
      ],
      "description": "A pathological (abnormal) structure or process.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PathologicalEntityMixin",
      "@type": "ClassDefinition"
    },
    {
      "name": "PathologicalProcess",
      "definition_uri": "https://w3id.org/biolink/vocab/PathologicalProcess",
      "exact_mappings": [
        "OBI:1110122",
        "NCIT:C16956"
      ],
      "narrow_mappings": [
        "NCIT:C19151",
        "EFO:0009708"
      ],
      "description": "A biologic function or a process having an abnormal or deleterious effect at the subcellular, cellular, multicellular, or organismal level.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalProcess",
      "mixins": [
        "PathologicalEntityMixin"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "has_input",
        "has_output",
        "enabled_by"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PathologicalProcess",
      "@type": "ClassDefinition"
    },
    {
      "name": "PathologicalProcessExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/PathologicalProcessExposure",
      "description": "A pathological process, when viewed as an exposure, representing an precondition, leading to or influencing an outcome, e.g. autoimmunity leading to disease.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PathologicalProcess",
      "mixins": [
        "ExposureEvent"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "has_input",
        "has_output",
        "enabled_by",
        "timepoint"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PathologicalProcessExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "PathologicalAnatomicalStructure",
      "definition_uri": "https://w3id.org/biolink/vocab/PathologicalAnatomicalStructure",
      "description": "An anatomical structure with the potential of have an abnormal or deleterious effect at the subcellular, cellular, multicellular, or organismal level.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "AnatomicalEntity",
      "mixins": [
        "PathologicalEntityMixin"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PathologicalAnatomicalStructure",
      "@type": "ClassDefinition"
    },
    {
      "name": "PathologicalAnatomicalExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/PathologicalAnatomicalExposure",
      "description": "An abnormal anatomical structure, when viewed as an exposure, representing an precondition, leading to or influencing an outcome, e.g. thrombosis leading to an ischemic disease outcome.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PathologicalAnatomicalStructure",
      "mixins": [
        "ExposureEvent"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon",
        "timepoint"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PathologicalAnatomicalExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "DiseaseOrPhenotypicFeatureExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeatureExposure",
      "description": "A disease or phenotypic feature state, when viewed as an exposure, represents an precondition, leading to or influencing an outcome, e.g. HIV predisposing an individual to infections; a relative deficiency of skin pigmentation predisposing an individual to skin cancer.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "DiseaseOrPhenotypicFeature",
      "mixins": [
        "ExposureEvent",
        "PathologicalEntityMixin"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "timepoint"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeatureExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "ChemicalExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/ChemicalExposure",
      "exact_mappings": [
        "ECTO:9000000",
        "SIO:001399"
      ],
      "description": "A chemical exposure is an intake of a particular chemical substance, other than a drug.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ChemicalSubstance",
      "mixins": [
        "ExposureEvent"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite",
        "timepoint"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ChemicalExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "ComplexChemicalExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/ComplexChemicalExposure",
      "description": "A complex chemical exposure is an intake of a chemical mixture (e.g. gasoline), other than a drug.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ChemicalExposure",
      "mixins": [
        "Mixture"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "is_metabolite",
        "timepoint",
        "has_constituent"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ComplexChemicalExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "DrugExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/DrugExposure",
      "aliases": [
        "drug intake",
        "drug dose",
        "medication intake"
      ],
      "exact_mappings": [
        "ECTO:0000509"
      ],
      "broad_mappings": [
        "SIO:001005"
      ],
      "description": "A drug exposure is an intake of a particular drug.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Drug",
      "mixins": [
        "ExposureEvent"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_constituent",
        "timepoint"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DrugExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "DrugToGeneInteractionExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/DrugToGeneInteractionExposure",
      "description": "drug to gene interaction exposure is a drug exposure is where the interactions of the drug with specific genes are known to constitute an 'exposure' to the organism, leading to or influencing an outcome.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "DrugExposure",
      "mixins": [
        "GeneGroupingMixin"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "in_taxon",
        "has_constituent",
        "timepoint",
        "has_gene_or_gene_product"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DrugToGeneInteractionExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "Treatment",
      "definition_uri": "https://w3id.org/biolink/vocab/Treatment",
      "aliases": [
        "medical action",
        "medical intervention"
      ],
      "exact_mappings": [
        "OGMS:0000090",
        "SIO:001398"
      ],
      "description": "A treatment is targeted at a disease or phenotype and may involve multiple drug 'exposures', medical devices and/or procedures",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "NamedThing",
      "mixins": [
        "ExposureEvent",
        "ChemicalOrDrugOrTreatment"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "has_drug",
        "has_device",
        "has_procedure",
        "timepoint"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Treatment",
      "@type": "ClassDefinition"
    },
    {
      "name": "BioticExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/BioticExposure",
      "aliases": [
        "viral exposure",
        "bacterial exposure"
      ],
      "description": "An external biotic exposure is an intake of (sometimes pathological) biological organisms (including viruses).",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "OrganismTaxon",
      "mixins": [
        "ExposureEvent"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "organism_taxon_has_taxonomic_rank",
        "organism_taxon_subclass_of",
        "timepoint"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/BioticExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "GeographicExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/GeographicExposure",
      "description": "A geographic exposure is a factor relating to geographic proximity to some impactful entity.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GeographicLocation",
      "mixins": [
        "ExposureEvent"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "latitude",
        "longitude",
        "timepoint"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeographicExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "EnvironmentalExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/EnvironmentalExposure",
      "description": "A environmental exposure is a factor relating to abiotic processes in the environment including sunlight (UV-B), atmospheric (heat, cold, general pollution) and water-born contaminants.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "EnvironmentalProcess",
      "mixins": [
        "ExposureEvent"
      ],
      "slots": [
        "id",
        "iri",
        "type",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "named_thing_category",
        "timepoint"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/EnvironmentalExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "BehavioralExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/BehavioralExposure",
      "description": "A behavioral exposure is a factor relating to behavior impacting an individual.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Behavior",
      "mixins": [
        "ExposureEvent"
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/BehavioralExposure",
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    },
    {
      "name": "SocioeconomicExposure",
      "definition_uri": "https://w3id.org/biolink/vocab/SocioeconomicExposure",
      "description": "A socioeconomic exposure is a factor relating to social and financial status of an affected individual (e.g. poverty).",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Behavior",
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/SocioeconomicExposure",
      "@type": "ClassDefinition"
    },
    {
      "name": "Outcome",
      "definition_uri": "https://w3id.org/biolink/vocab/Outcome",
      "description": "An entity that has the role of being the consequence of an exposure event. This is an abstract mixin grouping of various categories of possible biological or non-biological (e.g. clinical) outcomes.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Outcome",
      "@type": "ClassDefinition"
    },
    {
      "name": "PathologicalProcessOutcome",
      "definition_uri": "https://w3id.org/biolink/vocab/PathologicalProcessOutcome",
      "description": "An outcome resulting from an exposure event which is the manifestation of a pathological process.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PathologicalProcess",
      "mixins": [
        "Outcome"
      ],
      "slots": [
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PathologicalProcessOutcome",
      "@type": "ClassDefinition"
    },
    {
      "name": "PathologicalAnatomicalOutcome",
      "definition_uri": "https://w3id.org/biolink/vocab/PathologicalAnatomicalOutcome",
      "description": "An outcome resulting from an exposure event which is the manifestation of an abnormal anatomical structure.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "PathologicalAnatomicalStructure",
      "mixins": [
        "Outcome"
      ],
      "slots": [
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        "named_thing_category",
        "organismal_entity_has_attribute",
        "in_taxon"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PathologicalAnatomicalOutcome",
      "@type": "ClassDefinition"
    },
    {
      "name": "DiseaseOrPhenotypicFeatureOutcome",
      "definition_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeatureOutcome",
      "description": "Physiological outcomes resulting from an exposure event which is the manifestation of a disease or other characteristic phenotype.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "DiseaseOrPhenotypicFeature",
      "mixins": [
        "Outcome"
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      "slots": [
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeatureOutcome",
      "@type": "ClassDefinition"
    },
    {
      "name": "BehavioralOutcome",
      "definition_uri": "https://w3id.org/biolink/vocab/BehavioralOutcome",
      "description": "An outcome resulting from an exposure event which is the manifestation of human behavior.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Behavior",
      "mixins": [
        "Outcome"
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      "slots": [
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/BehavioralOutcome",
      "@type": "ClassDefinition"
    },
    {
      "name": "HospitalizationOutcome",
      "definition_uri": "https://w3id.org/biolink/vocab/HospitalizationOutcome",
      "description": "An outcome resulting from an exposure event which is the increased manifestation of acute (e.g. emergency room visit) or chronic (inpatient) hospitalization.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Hospitalization",
      "mixins": [
        "Outcome"
      ],
      "slots": [
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/HospitalizationOutcome",
      "@type": "ClassDefinition"
    },
    {
      "name": "MortalityOutcome",
      "definition_uri": "https://w3id.org/biolink/vocab/MortalityOutcome",
      "description": "An outcome of death from resulting from an exposure event.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Death",
      "mixins": [
        "Outcome"
      ],
      "slots": [
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/MortalityOutcome",
      "@type": "ClassDefinition"
    },
    {
      "name": "EpidemiologicalOutcome",
      "definition_uri": "https://w3id.org/biolink/vocab/EpidemiologicalOutcome",
      "related_mappings": [
        "NCIT:C19291"
      ],
      "description": "An epidemiological outcome, such as societal disease burden, resulting from an exposure event.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "BiologicalEntity",
      "mixins": [
        "Outcome"
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      "slots": [
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      "slot_usage": {},
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      "@type": "ClassDefinition"
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    {
      "name": "SocioeconomicOutcome",
      "definition_uri": "https://w3id.org/biolink/vocab/SocioeconomicOutcome",
      "description": "An general social or economic outcome, such as healthcare costs, utilization, etc., resulting from an exposure event",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Behavior",
      "mixins": [
        "Outcome"
      ],
      "slots": [
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/SocioeconomicOutcome",
      "@type": "ClassDefinition"
    },
    {
      "name": "Association",
      "definition_uri": "https://w3id.org/biolink/vocab/Association",
      "exact_mappings": [
        "OBAN:association",
        "rdf:Statement",
        "owl:Axiom"
      ],
      "description": "A typed association between two entities, supported by evidence",
      "comments": [
        "This is roughly the model used by biolink and ontobio at the moment"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Entity",
      "slots": [
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/Association",
      "@type": "ClassDefinition"
    },
    {
      "name": "ContributorAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/ContributorAssociation",
      "description": "Any association between an entity (such as a publication) and various agents that contribute to its realisation",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "slots": [
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ContributorAssociation",
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      "@type": "ClassDefinition"
    },
    {
      "name": "GenotypeToGenotypePartAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GenotypeToGenotypePartAssociation",
      "description": "Any association between one genotype and a genotypic entity that is a sub-component of it",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
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      "slot_usage": {},
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      "@type": "ClassDefinition"
    },
    {
      "name": "GenotypeToGeneAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GenotypeToGeneAssociation",
      "description": "Any association between a genotype and a gene. The genotype have have multiple variants in that gene or a single one. There is no assumption of cardinality",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
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        "genotype_to_gene_association_object"
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GenotypeToGeneAssociation",
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      "@type": "ClassDefinition"
    },
    {
      "name": "GenotypeToVariantAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GenotypeToVariantAssociation",
      "description": "Any association between a genotype and a sequence variant.",
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GenotypeToVariantAssociation",
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      "@type": "ClassDefinition"
    },
    {
      "name": "GeneToGeneAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneToGeneAssociation",
      "aliases": [
        "molecular or genetic interaction"
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      "description": "abstract parent class for different kinds of gene-gene or gene product to gene product relationships. Includes homology and interaction.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
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      "abstract": true,
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      "slot_usage": {},
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    },
    {
      "name": "GeneToGeneHomologyAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneToGeneHomologyAssociation",
      "description": "A homology association between two genes. May be orthology (in which case the species of subject and object should differ) or paralogy (in which case the species may be the same)",
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      "slot_usage": {},
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      "@type": "ClassDefinition"
    },
    {
      "name": "GeneExpressionMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneExpressionMixin",
      "description": "Observed gene expression intensity, context (site, stage) and associated phenotypic status within which the expression occurs.",
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      "name": "GeneToGeneCoexpressionAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneToGeneCoexpressionAssociation",
      "description": "Indicates that two genes are co-expressed, generally under the same conditions.",
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      "slot_usage": {},
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    },
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      "name": "PairwiseGeneToGeneInteraction",
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      "description": "An interaction between two genes or two gene products. May be physical (e.g. protein binding) or genetic (between genes). May be symmetric (e.g. protein interaction) or directed (e.g. phosphorylation)",
      "from_schema": "https://w3id.org/biolink/biolink-model",
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      "slot_usage": {},
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      "@type": "ClassDefinition"
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      "name": "PairwiseMolecularInteraction",
      "definition_uri": "https://w3id.org/biolink/vocab/PairwiseMolecularInteraction",
      "description": "An interaction at the molecular level between two physical entities",
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      "is_a": "PairwiseGeneToGeneInteraction",
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      "slot_usage": {},
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      "@type": "ClassDefinition"
    },
    {
      "name": "CellLineToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/CellLineToEntityAssociationMixin",
      "description": "An relationship between a cell line and another entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/CellLineToEntityAssociationMixin",
      "defining_slots": [
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      "@type": "ClassDefinition"
    },
    {
      "name": "CellLineToDiseaseOrPhenotypicFeatureAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/CellLineToDiseaseOrPhenotypicFeatureAssociation",
      "description": "An relationship between a cell line and a disease or a phenotype, where the cell line is derived from an individual with that disease or phenotype.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
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      "name": "MolecularEntityToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/MolecularEntityToEntityAssociationMixin",
      "description": "An interaction between a molecular entity and another entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/MolecularEntityToEntityAssociationMixin",
      "defining_slots": [
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      "@type": "ClassDefinition"
    },
    {
      "name": "DrugToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/DrugToEntityAssociationMixin",
      "description": "An interaction between a drug and another entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "MolecularEntityToEntityAssociationMixin",
      "mixin": true,
      "slots": [
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      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DrugToEntityAssociationMixin",
      "defining_slots": [
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      "@type": "ClassDefinition"
    },
    {
      "name": "ChemicalToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/ChemicalToEntityAssociationMixin",
      "description": "An interaction between a chemical entity and another entity",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "MolecularEntityToEntityAssociationMixin",
      "mixin": true,
      "slots": [
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      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ChemicalToEntityAssociationMixin",
      "defining_slots": [
        "subject"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "CaseToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/CaseToEntityAssociationMixin",
      "description": "An abstract association for use where the case is the subject",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "case_to_entity_association_mixin_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/CaseToEntityAssociationMixin",
      "defining_slots": [
        "subject"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "ChemicalToChemicalAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/ChemicalToChemicalAssociation",
      "description": "A relationship between two chemical entities. This can encompass actual interactions as well as temporal causal edges, e.g. one chemical converted to another.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "ChemicalToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "predicate",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "chemical_to_chemical_association_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ChemicalToChemicalAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "ChemicalToChemicalDerivationAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/ChemicalToChemicalDerivationAssociation",
      "description": "A causal relationship between two chemical entities, where the subject represents the upstream entity and the object represents the downstream. For any such association there is an implicit reaction:\n  IF\n  R has-input C1 AND\n  R has-output C2 AND\n  R enabled-by P AND\n  R type Reaction\n  THEN\n  C1 derives-into C2 <<catalyst qualifier P>>",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "ChemicalToChemicalAssociation",
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "chemical_to_chemical_derivation_association_catalyst_qualifier",
        "chemical_to_chemical_derivation_association_subject",
        "chemical_to_chemical_derivation_association_object",
        "chemical_to_chemical_derivation_association_predicate"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ChemicalToChemicalDerivationAssociation",
      "defining_slots": [
        "subject",
        "predicate",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "ChemicalToDiseaseOrPhenotypicFeatureAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/ChemicalToDiseaseOrPhenotypicFeatureAssociation",
      "narrow_mappings": [
        "SIO:000993"
      ],
      "description": "An interaction between a chemical entity and a phenotype or disease, where the presence of the chemical gives rise to or exacerbates the phenotype.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "ChemicalToEntityAssociationMixin",
        "EntityToDiseaseOrPhenotypicFeatureAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "predicate",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "chemical_to_disease_or_phenotypic_feature_association_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ChemicalToDiseaseOrPhenotypicFeatureAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "ChemicalToPathwayAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/ChemicalToPathwayAssociation",
      "exact_mappings": [
        "SIO:001250"
      ],
      "description": "An interaction between a chemical entity and a biological process or pathway.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "ChemicalToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "predicate",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "chemical_to_pathway_association_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ChemicalToPathwayAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "ChemicalToGeneAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/ChemicalToGeneAssociation",
      "exact_mappings": [
        "SIO:001257"
      ],
      "description": "An interaction between a chemical entity and a gene or gene product.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "ChemicalToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "predicate",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "chemical_to_gene_association_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ChemicalToGeneAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "DrugToGeneAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/DrugToGeneAssociation",
      "related_mappings": [
        "SIO:001257"
      ],
      "description": "An interaction between a drug and a gene or gene product.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "DrugToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "predicate",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "drug_to_gene_association_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DrugToGeneAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "MaterialSampleToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/MaterialSampleToEntityAssociationMixin",
      "description": "An association between a material sample and something.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "material_sample_to_entity_association_mixin_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/MaterialSampleToEntityAssociationMixin",
      "defining_slots": [
        "subject"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "MaterialSampleDerivationAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/MaterialSampleDerivationAssociation",
      "description": "An association between a material sample and the material entity from which it is derived.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "material_sample_derivation_association_subject",
        "material_sample_derivation_association_object",
        "material_sample_derivation_association_predicate"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/MaterialSampleDerivationAssociation",
      "defining_slots": [
        "subject",
        "predicate"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "MaterialSampleToDiseaseOrPhenotypicFeatureAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/MaterialSampleToDiseaseOrPhenotypicFeatureAssociation",
      "description": "An association between a material sample and a disease or phenotype.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "MaterialSampleToEntityAssociationMixin",
        "EntityToDiseaseOrPhenotypicFeatureAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "predicate",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/MaterialSampleToDiseaseOrPhenotypicFeatureAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "DiseaseToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/DiseaseToEntityAssociationMixin",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "disease_to_entity_association_mixin_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DiseaseToEntityAssociationMixin",
      "defining_slots": [
        "subject"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "EntityToExposureEventAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/EntityToExposureEventAssociationMixin",
      "description": "An association between some entity and an exposure event.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "entity_to_exposure_event_association_mixin_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/EntityToExposureEventAssociationMixin",
      "defining_slots": [
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "DiseaseToExposureEventAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/DiseaseToExposureEventAssociation",
      "description": "An association between an exposure event and a disease.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "DiseaseToEntityAssociationMixin",
        "EntityToExposureEventAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "predicate",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DiseaseToExposureEventAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "ExposureEventToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/ExposureEventToEntityAssociationMixin",
      "description": "An association between some exposure event and some entity.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "exposure_event_to_entity_association_mixin_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ExposureEventToEntityAssociationMixin",
      "defining_slots": [
        "subject"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "EntityToOutcomeAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/EntityToOutcomeAssociationMixin",
      "description": "An association between some entity and an outcome",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "entity_to_outcome_association_mixin_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/EntityToOutcomeAssociationMixin",
      "defining_slots": [
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "ExposureEventToOutcomeAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/ExposureEventToOutcomeAssociation",
      "description": "An association between an exposure event and an outcome.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "ExposureEventToEntityAssociationMixin",
        "EntityToOutcomeAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "predicate",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "has_population_context",
        "has_temporal_context"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ExposureEventToOutcomeAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "FrequencyQualifierMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/FrequencyQualifierMixin",
      "description": "Qualifier for frequency type associations",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "frequency_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/FrequencyQualifierMixin",
      "@type": "ClassDefinition"
    },
    {
      "name": "EntityToFeatureOrDiseaseQualifiersMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/EntityToFeatureOrDiseaseQualifiersMixin",
      "description": "Qualifiers for entity to disease or phenotype associations.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "FrequencyQualifierMixin",
      "mixin": true,
      "slots": [
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/EntityToFeatureOrDiseaseQualifiersMixin",
      "@type": "ClassDefinition"
    },
    {
      "name": "EntityToPhenotypicFeatureAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/EntityToPhenotypicFeatureAssociationMixin",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "EntityToFeatureOrDiseaseQualifiersMixin",
      "mixin": true,
      "slots": [
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "sex_qualifier",
        "entity_to_phenotypic_feature_association_mixin_description",
        "entity_to_phenotypic_feature_association_mixin_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/EntityToPhenotypicFeatureAssociationMixin",
      "defining_slots": [
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "EntityToDiseaseAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/EntityToDiseaseAssociationMixin",
      "description": "mixin class for any association whose object (target node) is a disease",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "EntityToFeatureOrDiseaseQualifiersMixin",
      "mixin": true,
      "slots": [
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "entity_to_disease_association_mixin_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/EntityToDiseaseAssociationMixin",
      "defining_slots": [
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "DiseaseOrPhenotypicFeatureToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeatureToEntityAssociationMixin",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "disease_or_phenotypic_feature_to_entity_association_mixin_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeatureToEntityAssociationMixin",
      "defining_slots": [
        "subject"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "DiseaseOrPhenotypicFeatureAssociationToLocationAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeatureAssociationToLocationAssociation",
      "deprecated": "This association class name is deprecated in favor of the 'disease or phenotypic feature to location association' class.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "DiseaseOrPhenotypicFeatureToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "predicate",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "disease_or_phenotypic_feature_association_to_location_association_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeatureAssociationToLocationAssociation",
      "@type": "ClassDefinition"
    },
    {
      "name": "DiseaseOrPhenotypicFeatureToLocationAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeatureToLocationAssociation",
      "description": "An association between either a disease or a phenotypic feature and an anatomical entity, where the disease/feature manifests in that site.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "DiseaseOrPhenotypicFeatureToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "predicate",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "disease_or_phenotypic_feature_to_location_association_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeatureToLocationAssociation",
      "@type": "ClassDefinition"
    },
    {
      "name": "EntityToDiseaseOrPhenotypicFeatureAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/EntityToDiseaseOrPhenotypicFeatureAssociationMixin",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "entity_to_disease_or_phenotypic_feature_association_mixin_object"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/EntityToDiseaseOrPhenotypicFeatureAssociationMixin",
      "defining_slots": [
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "GenotypeToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/GenotypeToEntityAssociationMixin",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "genotype_to_entity_association_mixin_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GenotypeToEntityAssociationMixin",
      "defining_slots": [
        "subject"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "GenotypeToPhenotypicFeatureAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GenotypeToPhenotypicFeatureAssociation",
      "description": "Any association between one genotype and a phenotypic feature, where having the genotype confers the phenotype, either in isolation or through environment",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "EntityToPhenotypicFeatureAssociationMixin",
        "GenotypeToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "genotype_to_phenotypic_feature_association_predicate",
        "genotype_to_phenotypic_feature_association_subject",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "sex_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GenotypeToPhenotypicFeatureAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "ExposureEventToPhenotypicFeatureAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/ExposureEventToPhenotypicFeatureAssociation",
      "description": "Any association between an environment and a phenotypic feature, where being in the environment influences the phenotype.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "EntityToPhenotypicFeatureAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "predicate",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "exposure_event_to_phenotypic_feature_association_subject",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "sex_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ExposureEventToPhenotypicFeatureAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "DiseaseToPhenotypicFeatureAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/DiseaseToPhenotypicFeatureAssociation",
      "description": "An association between a disease and a phenotypic feature in which the phenotypic feature is associated with the disease in some way.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "EntityToPhenotypicFeatureAssociationMixin",
        "DiseaseToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "predicate",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "sex_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/DiseaseToPhenotypicFeatureAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "CaseToPhenotypicFeatureAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/CaseToPhenotypicFeatureAssociation",
      "description": "An association between a case (e.g. individual patient) and a phenotypic feature in which the individual has or has had the phenotype.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "EntityToPhenotypicFeatureAssociationMixin",
        "CaseToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
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        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "sex_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/CaseToPhenotypicFeatureAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "BehaviorToBehavioralFeatureAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/BehaviorToBehavioralFeatureAssociation",
      "description": "An association between an aggregate behavior and a behavioral feature manifested by the individual exhibited or has exhibited the behavior.",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "EntityToPhenotypicFeatureAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "predicate",
        "relation",
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        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "behavior_to_behavioral_feature_association_subject",
        "behavior_to_behavioral_feature_association_object",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "sex_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/BehaviorToBehavioralFeatureAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneToEntityAssociationMixin",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "gene_to_entity_association_mixin_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeneToEntityAssociationMixin",
      "defining_slots": [
        "subject"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "VariantToEntityAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/VariantToEntityAssociationMixin",
      "local_names": [
        {
          "local_name_source": "ga4gh",
          "local_name_value": "variant annotation",
          "@type": "LocalName"
        }
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "variant_to_entity_association_mixin_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/VariantToEntityAssociationMixin",
      "defining_slots": [
        "subject"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneToPhenotypicFeatureAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneToPhenotypicFeatureAssociation",
      "exact_mappings": [
        "WBVocab:Gene-Phenotype-Association"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "EntityToPhenotypicFeatureAssociationMixin",
        "GeneToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "predicate",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "gene_to_phenotypic_feature_association_subject",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "sex_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeneToPhenotypicFeatureAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneToDiseaseAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneToDiseaseAssociation",
      "exact_mappings": [
        "SIO:000983"
      ],
      "comments": [
        "NCIT:R176 refers to the inverse relationship"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "EntityToDiseaseAssociationMixin",
        "GeneToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "predicate",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "gene_to_disease_association_subject",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeneToDiseaseAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "VariantToGeneAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/VariantToGeneAssociation",
      "description": "An association between a variant and a gene, where the variant has a genetic association with the gene (i.e. is in linkage disequilibrium)",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "VariantToEntityAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "variant_to_gene_association_object",
        "variant_to_gene_association_predicate"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/VariantToGeneAssociation",
      "defining_slots": [
        "subject",
        "predicate",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "VariantToGeneExpressionAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/VariantToGeneExpressionAssociation",
      "description": "An association between a variant and expression of a gene (i.e. e-QTL)",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "VariantToGeneAssociation",
      "mixins": [
        "GeneExpressionMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "subject",
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        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "variant_to_gene_association_object",
        "variant_to_gene_expression_association_predicate",
        "gene_expression_mixin_quantifier_qualifier",
        "expression_site",
        "stage_qualifier",
        "phenotypic_state"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/VariantToGeneExpressionAssociation",
      "defining_slots": [
        "subject",
        "predicate",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "VariantToPopulationAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/VariantToPopulationAssociation",
      "description": "An association between a variant and a population, where the variant has particular frequency in the population",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "VariantToEntityAssociationMixin",
        "FrequencyQuantifier",
        "FrequencyQualifierMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "predicate",
        "relation",
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        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "variant_to_population_association_subject",
        "variant_to_population_association_object",
        "variant_to_population_association_has_quotient",
        "variant_to_population_association_has_count",
        "variant_to_population_association_has_total",
        "has_percentage",
        "frequency_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/VariantToPopulationAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "PopulationToPopulationAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/PopulationToPopulationAssociation",
      "description": "An association between a two populations",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
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        "association_type",
        "association_category",
        "population_to_population_association_subject",
        "population_to_population_association_object",
        "population_to_population_association_predicate"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/PopulationToPopulationAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "VariantToPhenotypicFeatureAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/VariantToPhenotypicFeatureAssociation",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "VariantToEntityAssociationMixin",
        "EntityToPhenotypicFeatureAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "predicate",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "variant_to_phenotypic_feature_association_subject",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "sex_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/VariantToPhenotypicFeatureAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "VariantToDiseaseAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/VariantToDiseaseAssociation",
      "comments": [
        "TODO decide no how to model pathogenicity"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "VariantToEntityAssociationMixin",
        "EntityToDiseaseAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "variant_to_disease_association_subject",
        "variant_to_disease_association_predicate",
        "variant_to_disease_association_object",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/VariantToDiseaseAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "GenotypeToDiseaseAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GenotypeToDiseaseAssociation",
      "comments": [
        "TODO decide no how to model pathogenicity"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "GenotypeToEntityAssociationMixin",
        "EntityToDiseaseAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "genotype_to_disease_association_subject",
        "genotype_to_disease_association_predicate",
        "genotype_to_disease_association_object",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GenotypeToDiseaseAssociation",
      "defining_slots": [
        "subject",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "ModelToDiseaseAssociationMixin",
      "definition_uri": "https://w3id.org/biolink/vocab/ModelToDiseaseAssociationMixin",
      "description": "This mixin is used for any association class for which the subject (source node) plays the role of a 'model', in that it recapitulates some features of the disease in a way that is useful for studying the disease outside a patient carrying the disease",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "mixin": true,
      "slots": [
        "model_to_disease_association_mixin_subject",
        "model_to_disease_association_mixin_predicate"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/ModelToDiseaseAssociationMixin",
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneAsAModelOfDiseaseAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneAsAModelOfDiseaseAssociation",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GeneToDiseaseAssociation",
      "mixins": [
        "ModelToDiseaseAssociationMixin",
        "EntityToDiseaseAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "predicate",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "gene_as_a_model_of_disease_association_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeneAsAModelOfDiseaseAssociation",
      "defining_slots": [
        "subject",
        "predicate",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "VariantAsAModelOfDiseaseAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/VariantAsAModelOfDiseaseAssociation",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "VariantToDiseaseAssociation",
      "mixins": [
        "ModelToDiseaseAssociationMixin",
        "EntityToDiseaseAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
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        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "variant_to_disease_association_predicate",
        "variant_to_disease_association_object",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "variant_as_a_model_of_disease_association_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/VariantAsAModelOfDiseaseAssociation",
      "defining_slots": [
        "subject",
        "predicate",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "GenotypeAsAModelOfDiseaseAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GenotypeAsAModelOfDiseaseAssociation",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GenotypeToDiseaseAssociation",
      "mixins": [
        "ModelToDiseaseAssociationMixin",
        "EntityToDiseaseAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "genotype_to_disease_association_predicate",
        "genotype_to_disease_association_object",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "genotype_as_a_model_of_disease_association_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GenotypeAsAModelOfDiseaseAssociation",
      "defining_slots": [
        "subject",
        "predicate",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "CellLineAsAModelOfDiseaseAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/CellLineAsAModelOfDiseaseAssociation",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "CellLineToDiseaseOrPhenotypicFeatureAssociation",
      "mixins": [
        "ModelToDiseaseAssociationMixin",
        "EntityToDiseaseAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "predicate",
        "object",
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        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "cell_line_as_a_model_of_disease_association_subject",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/CellLineAsAModelOfDiseaseAssociation",
      "defining_slots": [
        "subject",
        "predicate",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "OrganismalEntityAsAModelOfDiseaseAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/OrganismalEntityAsAModelOfDiseaseAssociation",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "Association",
      "mixins": [
        "ModelToDiseaseAssociationMixin",
        "EntityToDiseaseAssociationMixin"
      ],
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "predicate",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "organismal_entity_as_a_model_of_disease_association_subject",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/OrganismalEntityAsAModelOfDiseaseAssociation",
      "defining_slots": [
        "subject",
        "predicate",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneHasVariantThatContributesToDiseaseAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneHasVariantThatContributesToDiseaseAssociation",
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "is_a": "GeneToDiseaseAssociation",
      "slots": [
        "id",
        "iri",
        "name",
        "description",
        "source",
        "provided_by",
        "has_attribute",
        "predicate",
        "object",
        "relation",
        "negated",
        "qualifiers",
        "publications",
        "association_type",
        "association_category",
        "frequency_qualifier",
        "severity_qualifier",
        "onset_qualifier",
        "sequence_variant_qualifier",
        "gene_has_variant_that_contributes_to_disease_association_subject"
      ],
      "slot_usage": {},
      "class_uri": "https://w3id.org/biolink/vocab/GeneHasVariantThatContributesToDiseaseAssociation",
      "defining_slots": [
        "subject",
        "predicate",
        "object"
      ],
      "@type": "ClassDefinition"
    },
    {
      "name": "GeneToExpressionSiteAssociation",
      "definition_uri": "https://w3id.org/biolink/vocab/GeneToExpressionSiteAssociation",
      "description": "An association between a gene and an expression site, possibly qualified by stage/timing info.",
      "notes": [
        "TBD: introduce subclasses for distinction between wild-type and experimental conditions?"
      ],
      "from_schema": "https://w3id.org/biolink/biolink-model",
      "see_also": [
        "https://github.com/monarch-initiative/ingest-artifacts/tree/master/sources/BGee"
      ],
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}
